1. Chemicals in combination can produce different biological responses than
the responses seen when exposure is to one chemical alone.
True
False: True
2. ________ is the most common route of exposure leading to a toxic dose in
the work environment
Injection
Ingestion
Inhalation
Eye/Skin contact:
3. LD 50 of 25 mg/m3 means that a concentration of 25 mg/m3 of a certain
substance indicates:
50 people out of a group of 80 exposed to a concentration 25 mg/m3 of a
substance were shown to have experienced a fatal dose.
50% of the concentration of a substance cause fatality in those be exposed.
A concentration of 25 mg/m3 of a substance is shown to have been fatal to 50
percent of a test group of animals.
LD 50 is a fictitious term and does not indicate anything.:
A concentration of 25 mg/m3 of a substance is shown to have been fatal to 50
percent of a test group of animals.
4. Factors affecting response to chemical exposure include:
Toxicity
Route of exposure
Chemical dose
All of the above:
All of the above
5. ________ provide most of what we know about the dangerous effects of
toxic substances.
Epidemiological studies
Animal studies
Estimation studies
Actual exposures to a chemical in the workplace: Epidemiological studies
Animal studies 1/5
, HAZWOPER 40 - Lesson 3 - Toxicology
6. Example of chemical ________ are carbon monoxide and hydrogen cyanide.
Hepatoxins
Hematoxins
Asphyxiants
Nephrotoxins: Asphyxiants
7. The ACGIH publication: ________ for Chemical Substances and Physical
Agents, OSHA standard 29 CFR part 1910.1000, and other standards reference
identify substances that can be readily absorbed through the skin, mucous
membranes, and/or eyes by either airborne exposures or direct contact with
a liquid.
Threshold Limit Values
HAZCOM
Right-to-know
SDS: Threshold Limit Values
8. Polyurethane foam, when burnt, gives off:
Sulfuric acid
Cyanide gas
Ethane
Phosphine: Cyanide gas
9. Animal studies provide most of what we know about the dangerous effects
of toxic substances. Humans may react differently than animals exposed to
toxic materials.
False
True: True
10. A(n) ________ is the airborne concentration of a material to which nearly
all individuals may be repeatedly expose without adverse health effects.
Chemical exposure
Sensitizer threshold
Exposure limit
Irritant level: Exposure limit
11. When a chemical with no known toxic effects acts together with a known
toxic substance to make the combined toxic substance even more potent, this
is called ________ interaction.
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