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The pancreas is level with what vertebra? - ✔✔L1
Pancreas arterial supply and their origin - ✔✔The superior pancreaticoduodenal artery
arises from the gastroduodenal artery and divides into anterior and posterior branches
as it runs inferiorly within the pancreaticoduodenal groove. The inferior
pancreaticoduodenal artery arises from SMA. The neck, body, and tail receive arterial
supply from the splenic arterial system.
Rotation during pancreatic fusion - ✔✔Ventral posteriorly
Treatment for obstructive annular pancreas - ✔✔surgical bypass through
duodenojejunostomy is performed instead of dividing the pancreatic tissue, as this
annular pancreas has a pancreatic duct and its division will likely lead to pancreatic
fistula formation.
How are pancreatic enzymes activated? - ✔✔acinar cells synthesize these proteases as
inactive proenzymes that are stored as intracellular zymogen granules. With
stimulation of the pancreas, these proenzymes are secreted into the pancreatic duct and
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, eventually the duodenal lumen. The duodenal mucosa expresses enterokinase on its
brush boarder, which activates the zymogens.
main mediator of the secretion of water and bicarbonate from pancreas - ✔✔Secretin
from S cells
What stimulates secretin secretion? - ✔✔Decrease in duodenal pH
main mediator of the secretion of pancreatic enzymes - ✔✔CCK by I cells
Most common cause of acute pancreatitis - ✔✔Gall stones
Treatment for pancreatic divisum - ✔✔Endoscopic retrograde
cholangiopancreatography (ERCP) with minor papillotomy and stenting
Describe acute pancreatitis pain - ✔✔Constant epigastric pain that radiates to the back
Grey Turner and Cullen signs - ✔✔flank and periumbilical ecchymosis respectively,
both are indicative of retroperitoneal bleeding associated with severe pancreatitis.
Diagnosis of acute pancreatitis - ✔✔two of the following three:
1) abdominal pain consistent with AP
2) a threefold or higher elevation of serum amylase or lipase
3) characteristics findings of pancreatitis by imaging.
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