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1. oxygen used in tissue
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2. Arterial oxygen pressure goes down
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3. Erythropoiesis goes UP
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.4. Stem cell stimulation goes UP
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5. RBC formed
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6. O2 capacity UP
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7. Arterial oxygen pressure UP
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8. Stimulation for erythropoietin DOWN (back to 1)
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Erythropoiesis stimulating agents - correct answer ✔Stimulate bone marrow
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to make RBCs
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Epoetin Alfa (Epogen or Procrit)
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anemia associates w/: |! |! |!
renal fail |! |!
aids
Darbepoetin Alfa (Aranesp) |! |! |!
anemia associated with chronic kidney disease + dialysis pts
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, Anemia - correct answer ✔Disorder with too few or inefficient RBCs
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SIGNS: |!
shortness breath |!
change stool color |! |!
muscle pain |!
fainting + fatigue |! |!
angina + HA |! |!
spleen enlarge |!
skin yellowing
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clubbing
-cytic - correct answer ✔cell size (hypo / hyper)
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-chromic - correct answer ✔HBG content (Hypo / hyper)
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Microcytic anemia - correct answer ✔abnormally small RBC
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EX: Fe lack, thalassemia
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macrocytic anemia - correct answer ✔Large, thick RBCs
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EX: folate + B12 lack
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Normocytic anemia - correct answer ✔normal size and appearance RBC
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