BASIC AND CLINICAL PHARMACOLOGY 15TH EDITIONKA
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TZUNG TREVOR TEST BANK
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INCLUSIVErOFrCHAPTERSr1-66rCOMPLETErWITHrEXPLAINEDrANSWERS
, Pager2rofr822
Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapterr1.rIntroduction:rTherNaturerofrDrugsr&rDrugrDevelopmentr&rRegulation
1.
Arnurserworkingrinrradiologyradministersriodinertorarpatientrwhorisrhavingrarc
omputedrtomographyr(CT)rscan.rThernurserworkingronrtheroncologyrunitradmin
istersrchemotherapyrtorpatientsrwhorhavercancer.rAtrtherPublicrHealthrDepartme
nt,rarnurseradministersrarmeasles-mumps-rubellar(MMR)rvaccinertorar14-
month-
oldrchildrasrarroutinerimmunization.rWhichrbranchrofrpharmacologyrbestrdescri
besrtheractionsrofrallrthreer nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologyrisrtherstudyrofrtherbiologicreffectsrofrchemicals.rNursesrarerinvol
vedrwithrclinicalrpharmacologyrorrpharmacotherapeutics,rwhichrisrarbranchrofrp
harmacologyrthatrdealsrwithrtherusesrofrdrugsrtortreat,rprevent,randrdiagnoserdis
ease.rTherradiologyrnurserisradministeringrardrugrtorhelprdiagnoserardisease.rTh
eroncologyrnurserisradministeringrardrugrtorhelprtreatrardisease.rPharmacoecono
micsrincludesranyrcostsrinvolvedrinrdrugrtherapy.
Pharmacodynamicsrinvolvesrhowrardrugraffectsrtherbodyrandrpharmacokineticsri
srhowrtherbodyractsronrtherbody.
2.
WhenrinvolvedrinrphaserIIIrdrugrevaluationrstudies,rwhatr
responsibilitiesrwouldrthernurserhave?
A) Workingrwithranimalsrwhorarergivenrexperimentalr drugs
B) Choosingrappropriaterpatientsrtorberinvolvedrinrtherdrugr study
C) Monitoringrandrobservingrpatientsrcloselyrforradverser effects
D) Conductingrresearchrtordeterminereffectivenessrofrther drug
, Pager3rofr822
Ans: C
Feedback:
PhaserIIIrstudiesrinvolveruserofrardrugrinrarvastrclinicalrpopulationrinrwhichrpati
entsrareraskedrtorrecordranyrsymptomsrtheyrexperiencerwhilertakingrtherdrugs.r
Nursesrmayrberresponsiblerforrhelpingrcollectrandranalyzertherinformationrtorb
ersharedrwithrtherFoodrandrDrugrAdministrationr(FDA)rbutrwouldrnotrconductr
researchrindependentlyrbecausernursesrdornotrprescribermedications.rUserofra
nimalsrinrdrugrtestingrisrdonerinrtherpreclinicalrtrials.rSelectrpatientsrwhorarerin
volvedrinrphaserIIrstudiesrtorparticipaterinrstudiesrwherertherparticipantsrhavert
herdiseasertherdrugrisrintendedrtortreat.rTheserpatientsrarermonitoredrcloselyrfo
rrdrugractionrandradversereffects.rPhaserIrstudiesrinvolverhealthyrhumanrvolun
teersrwhorarerusuallyrpaidrforrtheirrparticipation.rNursesrmayrobserverforradve
rsereffectsrandrtoxicity.
3.
Arphysicianrhasrorderedrintramuscularr(IM)rinjectionsrofrmorphine,rarnarcoti
c,reveryr4rhoursrasrneededrforrpainrinrarmotorrvehicleraccidentrvictim.rThernurser
israwarerthisrdrugrhasrarhighrabuserpotential.rUnderrwhatrcategoryrwouldrmorph
inerberclassified?
A) SchedulerI
B) SchedulerII
C) SchedulerIII
D) SchedulerIV
Ans: B
Feedback:
NarcoticsrwithrarhighrabuserpotentialrarerclassifiedrasrSchedulerIIrdrugsrbecau
serofrsevererdependencerliability.rSchedulerIrdrugsrhaverhighrabuserpotentialra
ndrnoracceptedrmedicalruse.rSchedulerIIIrdrugsrhaverarlesserrabuserpotentialrth
anrIIrandranracceptedrmedicalruse.rSchedulerIVrdrugsrhaverlowrabuserpotentialra
ndrlimitedrdependencer liability.
4.
Whatrconceptrisrconsideredrwhenrgenericrdrugsrarersubstitutedrforrbrandr
namerdrugs?
A) Bioavailability
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