QUESTIONS & ANSWERS VERIFIED
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1 of 130
Term
What is the recommended treatment for latent M. tuberculosis?
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Rifapentine + isoniazid once
Identifies the net cost impact of the
weekly x3 months
intervention
Compare programs or agents with Rafampin daily x4 months
Rifampin + isoniazid dialy x3
different objectives
months
, lamivudine, abacavir, glecaprevir/pibrentasvir (Mavyret) -
tenofovir disoproxil fumarate, typically x8 weeks
tenofovir alafenamide, sofosbuvir/velpatisvir (Epclusa) -
emtricitabine typically x12 weeks
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2 of 130
Term
When do you initiate ART in oropharyngeal candidiasis?
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Start ART as part of Stop art during oropharyngeal
OI management candidiasis
Delay art until symptoms resolve Switch art to a different regimen
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3 of 130
Term
What are the pan-genotypic treatment regimens for hep C?
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, > 70 y/o
Immunosuppression
Malignancy
Preexisting chronic liver/kidney disease
High APACHE score > 15
HA infections
Delay in initial intervention (>24 hrs)
Inability to obtain course control
glecaprevir/pibrentasvir (Mavyret) - typically x8 weeks
sofosbuvir/velpatisvir (Epclusa) - typically x12 weeks
1. Predisposition, predisposing heart condition, IVDU
2.Fever > 38C
3.Vascular phenomena - major arterial emboli, septic pulmonary infarcts,
mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhage, Janeway
lesions
4. Immunological phenomena - glomerulonephritis, Osler nodes, Roth spots,
rheumatoid fever
5. Microbiological evidence - positive bcx not meeting major criteria (except
single CoNS and orgs that don't cause IE) or serologic evidence of
active infection with organism consistent with IE
sofosbuvir/velpatisvir/voxilaprevir (Vosevi)
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4 of 130
Term
What is the best treatment for CMV with a UL54 mutation?
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Identifies the net cost impact of the
PPI + clarithromycin + amoxicillin (or
intervention
metronidazole) x14 days
Compare programs or agents with
different objectives
May confer resistance to
Rifapentine + isoniazid once
valganciclovir, ganciclovir,
weekly x3 months
foscarnet, cidofovir
Rafampin daily x4 months
Treatment choice dependent
Rifampin + isoniazid dialy x3 months
on specific mutation
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5 of 130
Definition
TP/(TP+FN)
Reliable to detect disease when actually present
High sensitivity = low false negative
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Accuracy Reliability
Sensitivity Specificity
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