Test Bank For Basic Pharmacology for Nurses 17th Edition by Michelle Willihnganz,
Bruce D. Clayton Chapter 1-48
TABLE OF CONTENTS.
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1: Drug Definitions, Standards, and Information Sources Chapter 01: Drug Definitions, Standards, and Information Sources
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Chapter 3: Drug Action Across the Life Span Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition
Chapter 4: The Nursing Process and Pharmacology
Chapter 5: Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration MULTIPLE CHOICE
Chapter 6: Principles of Medication Administration and Medication Safety
Chapter 7: Percutaneous Administration 1. What is the name under which a drug is listed by the US Food and Drug
Chapter 8: Enteral Administration
Chapter 9: Parenteral Administration: Safe Preparation of Parenteral Medications
Administration (FDA)?
Chapter 10: Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular a. Brand
Routes b. Nonproprietary
Chapter 11: Parenteral Administration: Intravenous Route c. Official
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems d. Trademark
Chapter 12: Drugs Affecting the Autonomic Nervous System
Chapter 13: Drugs Used for Sleep ANS: C
Chapter 14: Drugs Used for Neurodegenerative Disorders (NEW!) The official name is the name under which a drug is listed by the FDA.
Chapter 15: Drugs Used for Anxiety Disorders The brand name, or trademark, is the name given to a drug by its
Chapter 16: Drugs Used for Depressive and Bipolar Disorders
Chapter 17: Drugs Used for Psychoses manufacturer. The nonproprietary, or generic, name is provided by the
Chapter 18: Drugs Used for Seizure Disorders United States Adopted Names Council.
Chapter 19: Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 1
Chapter 20: Introduction to Cardiovascular Disease and Metabolic Syndrome NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
Chapter 21: Drugs Used to Treat Dyslipidemias TOP:NursingProcess Step: Assessment CON: Patient Education
Chapter 22: Drugs Used to Treat Hypertension
Chapter 23: Drugs Used to Treat Dysrhythmias
2. Which source contains information specific to nutritional supplements?
Chapter 24: Drugs Used to Treat Angina Pectoris
Chapter 25: Drugs Used to Treat Peripheral Vascular Disease
a. USP Dictionary of USAN & International Drug Names
Chapter 26: Drugs Used to Treat Thromboembolic Disorders b. Natural Medicines Comprehensive Database
Chapter 27: Drugs Used to Treat Heart Failure c. United States Pharmacopoeia/National Formulary (USP NF)
Chapter 28: Drugs Used for Diuresis d. Drug Interaction Facts
Unit 5: Drugs Affecting the Respiratory System
Chapter 29: Drugs Used to Treat Upper Respiratory Disease ANS: C
Chapter 30: Drugs Used to Treat Lower Respiratory Disease United States Pharmacopoeia/National Formulary contains information specific to nutritional
Unit 6: Drugs Affecting the Digestive System supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
Chapter 31: Drugs Used to Treat Oral Disorders
Chapter 32: Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
names, pronunciation guide, and possible future FDA approved drugs; it does not include
Chapter 33: Drugs Used to Treat Nausea and Vomiting nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based
Chapter 34: Drugs Used to Treat Constipation and Diarrhea information on herbal medicines and herbal combination products; it does not include
Unit 7: Drugs That Affect the Endocrine System information specific to nutritional supplements. Drug Interaction Facts contains comprehensive
Chapter 35: Drugs Used to Treat Diabetes Mellitus information on drug interaction facts; it does not include nutritional supplements.
Chapter 36: Drugs Used to Treat Thyroid Disease
Chapter 37: Corticosteroids
DIF: Cognitive Level: Knowledge REF: p. 2 | p. 3 OBJ: 3
Chapter 38: Gonadal Hormones
Unit 8: Drugs Affecting the Reproductive System
NAT:NCLEXClient NeedsCategory: Physiological Integrity
Chapter 39: Drugs Used in Obstetrics TOP:NursingProcess Step: Assessment CON: Nutrition | Patient Education
Chapter 40: Drugs Used in Men‘s and Women‘s Health
Unit 9: Drugs Affecting Other Body Systems 3. What is the most comprehensive reference available to research a drug interaction?
Chapter 41: Drugs Used to Treat Disorders of the Urinary System a. Drug Facts and Comparisons
Chapter 42: Drugs Used to Treat Glaucoma and Other Eye Disorders b. Drug Interaction Facts
Chapter 43: Drugs Used to Treat Cancer c. Handbook on Injectable Drugs
Chapter 44: Drugs Used to Treat the Musculoskeletal System
Chapter 45: Drugs Used to Treat Infection Unit 10: Drugs Affecting the General Health of the Body d. Martindale—The Complete Drug Reference
Chapter 46: Nutrition
Chapter 47: Herbal and Dietary Supplemental Therapy
Chapter 48: Substance Abuse
, ANS: B a. Federal Food, Drug, and Cosmetic Act (1938)
First published in 1983, Drug Interaction Facts is the most comprehensive book available on b. Durham Humphrey Amendment (1952)
drug interactions. In addition to monographs listing various aspects of drug interactions, this c. Controlled Substances Act (1970)
information is reviewed and updated by an internationally renowned group of physicians and d. Kefauver Harris Drug Amendment (1962)
pharmacists with clinical and scientific expertise.
ANS: A
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3 The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
NAT:NCLEXClient NeedsCategory: Physiological Integrity of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
TOP:NursingProcess Step: Assessment CON: Safety | Patient Education | Clinical Judgment drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
safely without medical supervision and restricts their sale to prescription by a licensed
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section practitioner. The Controlled Substances Act addresses only controlled substances and their
of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug? categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
a. Manufacturer‘s section safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
b. Brand and Generic name section before marketing them.
c. Product category section
d. Product information section DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 6
NAT:NCLEXClient NeedsCategory: Physiological Integrity
ANS: B TOP:NursingProcess Step: Assessment
A physician‘s order would include the brand and/or generic name of the drug. The alphabetic CON: Safety | Patient Education | Evidence | Health Care Law
index in the PDR would make this section the most user-friendly. Based on a physician‘s order,
manufacturer‘s information and classification information would not be known. The 7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
Manufacturer‘s section is a roster of manufacturers. The product category section lists products dependency. Under which classification does this drug fall?
subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The a. I
product information section contains reprints of the package inserts for the major products of b. II
manufacturers. c. III
d. IV
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity ANS: B
TOP:NursingProcess Step: Planning CON: Safety | Patient Education | Clinical Judgment Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
5. Which online drug reference makes available to healthcare providers and the public a standard, and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
comprehensive, up-to-date look up and downloadable resource about medicines? to low to moderate physical dependence or high psychological dependence. Schedule IV drugs
a. American Drug Index have low potential for abuse. Use may lead to limited physical or psychological dependence.
b. American Hospital Formulary
c. DailyMed DIF: Cognitive Level: Comprehension REF: p. 5 OBJ: 2
d. Physicians’ Desk Reference (PDR) NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education | Addiction | Pain
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive, up- 8. What would the FDA do to expedite drug development and approval for an outbreak of
to-date look up and downloadable resource about medicines. The American Drug Index is not smallpox, for which there is no known treatment?
appropriate for patient use. The American Hospital Formulary is not appropriate for patient use. a. List smallpox as a health orphan disease.
The PDR is not appropriate for patient use. b. Omit the preclinical research phase.
c. Extend the clinical research phase.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 5 OBJ: 4 d. Fast track the investigational drug.
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Implementation ANS: D
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
, Once the Investigational New Drug Application has been approved, the drug can receive highest
ANS: A
priority within the agency, which is called fast tracking. A smallpox outbreak would become a Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
priority concern in the world. Orphan diseases are not researched in a priority manner. dependence liability compared with drugs in Schedule IV. Because abuse potential is low with a
Preclinical research is not omitted. Extending any phase of the research would mean a longer
Schedule V drug, a prescription may not be required. Psychological dependency is not likely
time to develop a vaccine. The FDA must ensure that all phases of the preclinical and clinical with a Schedule V drug. Schedule V drugs are classified as controlled substances.
research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 6 OBJ: 2
DIF: Cognitive Level: Knowledge REF: p. 8 OBJ: 6 NAT:NCLEXClient NeedsCategory: Physiological Integrity
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety | Patient Education
TOP:NursingProcess Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination 12. The nurse is transcribing new orders written for a patient with a substance abuse history. Choose
the medication ordered that has the greatest risk for abuse.
9. Which statement is true about over-the-counter (OTC) drugs?
a. Lomotil
a. They are not listed in the USP NF.
b. Diazepam
b. A prescription from a healthcare provider is needed.
c. Phenobarbital
c. They are sold without a prescription.
d. Lortab
d. They are known only by their brand names.
ANS: D
ANS: C
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in Schedules I
OTC medications do not require a prescription. A variety of names, both generic and trade, can
and II. Lomotil is a Schedule V drug with a low potential for abuse compared with those in
be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription drugs
Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse compared with those
require an order by a health professional who is licensed to prescribe, such as a physician, nurse
in schedule III. Phenobarbital is a Schedule IV drug with a low potential for abuse compared
practitioner, physician assistant, or dentist.
with those in Schedule III.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
DIF: Cognitive Level: Application REF: p. 6 OBJ: 2
NAT:NCLEXClient NeedsCategory: Physiological Integrity
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Planning CON: Patient Education
TOP:NursingProcess Step: Assessment CON: Addiction | Patient Education | Safety
10. Which is the most authoritative reference for medications that are injected?
a. Physicians’ Desk Reference MULTIPLE RESPONSE
b. Handbook on Injectable Drugs
c. DailyMed 1. An older adult experiencing shortness of breath is brought to the hospital by her daughter. While
d. Handbook of Nonprescription Drugs obtaining the medication history from the patient and her daughter, the nurse discovers that
neither has a list of the patient‘s current medications or prescriptions. All the patient has is a
ANS: B weekly pill dispenser that contains four different pills. The prescriptions are filled through the
The Handbook on Injectable Drugs is the most comprehensive reference available on the topic of local pharmacy. Which resource(s) would be appropriate to use in determining the medication
compatibility of injectable drugs. It is a collection of monographs for more than 300 injectable names and doses? (Select all that apply.)
drugs that are listed alphabetically by generic name. a. Martindale—The Complete Drug Reference
b. Physicians’ Desk Reference, Section 4
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
c. Senior citizens‘ center
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety d. Patient‘s home pharmacy
ANS: B, D
11. The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this drug‘s The Physicians’ Desk Reference, Section 4, has full color images of commonly dispensed tablets
classification? and capsules. The patient‘s pharmacy would have an accurate account of all the medications the
a. Abuse potential for this drug is low. client is currently taking. Martindale—The Complete Drug Reference has written information on
b. Psychological dependency is likely. medications and would not be an appropriate resource. The senior citizens‘ center is not likely to
c. There is a high potential for abuse.
have specific patient medication information.
d. This drug is not a controlled substance.
, DIF: Cognitive Level: Application REF: p. 3 | p. 4 OBJ: 3 1. The nurse assesses hives in a patient started on a new medication. What is the nurse‘s priority
NAT:NCLEXClient NeedsCategory: Physiological Integrity action?
TOP:NursingProcess Step: Assessment a. Notify physician of allergic reaction.
CON: Care Coordination | Safety | Patient Education | Clinical Judgment b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
2. The nurse planning patient teaching regarding drug names would include which statement(s)? d. Notify physician of potential tolerance.
(Select all that apply.)
a. Most drug companies place their products on the market under generic names. ANS: A
b. The official name is the name under which the drug is listed by the US Food and An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
Drug Administration (FDA). which are easily identified. An idiosyncratic reaction occurs when something unusual or
c. Brand names are easier to pronounce, spell, and remember. abnormal happens when a drug is first administered. A teratogenic reaction refers to the
d. The first letter of the generic name is not capitalized. occurrence of birth defects related to administration of the drug. Tolerance refers to the body‘s
e. The chemical name is most meaningful to the patient. requirement for increasing dosages to achieve the same effects that a lower dose once did.
ANS: B, C, D DIF: Cognitive Level: Application REF: p. 17 OBJ: 4
The official name is the name under which the drug is listed by the FDA. Brand names are easier NAT:NCLEXClient NeedsCategory: Physiological Integrity
to pronounce, spell, and remember. The first letter of the generic name is not capitalized. Most TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety
drug companies place their products on the market under brand names instead of generic names.
The chemical name is most meaningful to the chemist. 2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes after
administration, the nurse finds the patient agitated and stating that ―everyone is out to get me.‖
DIF: Cognitive Level: Application REF: p. 1 | p. 2 OBJ: 1 What is the term for this unusual reaction?
NAT:NCLEXClient NeedsCategory: Physiological Integrity a. Desired action
TOP:NursingProcess Step: Planning CON: Patient Education | Clinical Judgment | Safety b. Adverse effect
c. Idiosyncratic reaction
3. When categorizing, the nurse is aware that which drug(s) would be considered Schedule II? d. Allergic reaction
(Select all that apply.)
a. Marijuana ANS: C
b. Percodan Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
c. Amphetamines administered. Patients typically exhibit an overresponsiveness to a medication related to
d. Fiorinal diminished metabolism. These reactions are believed to be related to genetic enzyme
e. Flurazepam deficiencies. Desired actions are expected responses to a medication. Adverse effects are
reactions that occur in another system of the body; they are usually predictable. Allergic
ANS: B, C reactions appear after repeated medication dosages.
Schedule II drugs have a high potential for abuse, they are currently accepted in the United
States, and use may lead to severe psychological or physical dependence. Percodan and DIF: Cognitive Level: Knowledge REF: p. 18 OBJ: 4
amphetamines are considered Schedule II drugs. Marijuana is a Schedule I drug. Fiorinal is a NAT:NCLEXClient NeedsCategory: Physiological Integrity
Schedule III drug. Flurazepam is a Schedule IV drug. TOP:NursingProcess Step: Evaluation
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
DIF: Cognitive Level: Analysis REF: p. 5 | p. 6 OBJ: 2
NAT:NCLEXClient NeedsCategory: Physiological Integrity 3. Which is the best description of when drug interactions occur?
TOP:NursingProcess Step: Assessment CON: Addiction | Clinical Judgment | Patient Education a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
Chapter 02: Basic Principles of Drug Action and Drug Interactions c. On the alteration of the effect of one drug by another drug
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition d. On increase of drug excretion
ANS: C
MULTIPLE CHOICE
Bruce D. Clayton Chapter 1-48
TABLE OF CONTENTS.
Unit 1: Applying Pharmacology to Nursing Practice
Chapter 1: Drug Definitions, Standards, and Information Sources Chapter 01: Drug Definitions, Standards, and Information Sources
Chapter 2: Basic Principles of Drug Action and Drug Interactions
Chapter 3: Drug Action Across the Life Span Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition
Chapter 4: The Nursing Process and Pharmacology
Chapter 5: Patient Education to Promote Health
Unit 2: Illustrated Atlas of Medication Administration MULTIPLE CHOICE
Chapter 6: Principles of Medication Administration and Medication Safety
Chapter 7: Percutaneous Administration 1. What is the name under which a drug is listed by the US Food and Drug
Chapter 8: Enteral Administration
Chapter 9: Parenteral Administration: Safe Preparation of Parenteral Medications
Administration (FDA)?
Chapter 10: Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular a. Brand
Routes b. Nonproprietary
Chapter 11: Parenteral Administration: Intravenous Route c. Official
Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems d. Trademark
Chapter 12: Drugs Affecting the Autonomic Nervous System
Chapter 13: Drugs Used for Sleep ANS: C
Chapter 14: Drugs Used for Neurodegenerative Disorders (NEW!) The official name is the name under which a drug is listed by the FDA.
Chapter 15: Drugs Used for Anxiety Disorders The brand name, or trademark, is the name given to a drug by its
Chapter 16: Drugs Used for Depressive and Bipolar Disorders
Chapter 17: Drugs Used for Psychoses manufacturer. The nonproprietary, or generic, name is provided by the
Chapter 18: Drugs Used for Seizure Disorders United States Adopted Names Council.
Chapter 19: Drugs Used for Pain Management
Unit 4: Drugs Affecting the Cardiovascular System DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 1
Chapter 20: Introduction to Cardiovascular Disease and Metabolic Syndrome NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
Chapter 21: Drugs Used to Treat Dyslipidemias TOP:NursingProcess Step: Assessment CON: Patient Education
Chapter 22: Drugs Used to Treat Hypertension
Chapter 23: Drugs Used to Treat Dysrhythmias
2. Which source contains information specific to nutritional supplements?
Chapter 24: Drugs Used to Treat Angina Pectoris
Chapter 25: Drugs Used to Treat Peripheral Vascular Disease
a. USP Dictionary of USAN & International Drug Names
Chapter 26: Drugs Used to Treat Thromboembolic Disorders b. Natural Medicines Comprehensive Database
Chapter 27: Drugs Used to Treat Heart Failure c. United States Pharmacopoeia/National Formulary (USP NF)
Chapter 28: Drugs Used for Diuresis d. Drug Interaction Facts
Unit 5: Drugs Affecting the Respiratory System
Chapter 29: Drugs Used to Treat Upper Respiratory Disease ANS: C
Chapter 30: Drugs Used to Treat Lower Respiratory Disease United States Pharmacopoeia/National Formulary contains information specific to nutritional
Unit 6: Drugs Affecting the Digestive System supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
Chapter 31: Drugs Used to Treat Oral Disorders
Chapter 32: Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease
names, pronunciation guide, and possible future FDA approved drugs; it does not include
Chapter 33: Drugs Used to Treat Nausea and Vomiting nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based
Chapter 34: Drugs Used to Treat Constipation and Diarrhea information on herbal medicines and herbal combination products; it does not include
Unit 7: Drugs That Affect the Endocrine System information specific to nutritional supplements. Drug Interaction Facts contains comprehensive
Chapter 35: Drugs Used to Treat Diabetes Mellitus information on drug interaction facts; it does not include nutritional supplements.
Chapter 36: Drugs Used to Treat Thyroid Disease
Chapter 37: Corticosteroids
DIF: Cognitive Level: Knowledge REF: p. 2 | p. 3 OBJ: 3
Chapter 38: Gonadal Hormones
Unit 8: Drugs Affecting the Reproductive System
NAT:NCLEXClient NeedsCategory: Physiological Integrity
Chapter 39: Drugs Used in Obstetrics TOP:NursingProcess Step: Assessment CON: Nutrition | Patient Education
Chapter 40: Drugs Used in Men‘s and Women‘s Health
Unit 9: Drugs Affecting Other Body Systems 3. What is the most comprehensive reference available to research a drug interaction?
Chapter 41: Drugs Used to Treat Disorders of the Urinary System a. Drug Facts and Comparisons
Chapter 42: Drugs Used to Treat Glaucoma and Other Eye Disorders b. Drug Interaction Facts
Chapter 43: Drugs Used to Treat Cancer c. Handbook on Injectable Drugs
Chapter 44: Drugs Used to Treat the Musculoskeletal System
Chapter 45: Drugs Used to Treat Infection Unit 10: Drugs Affecting the General Health of the Body d. Martindale—The Complete Drug Reference
Chapter 46: Nutrition
Chapter 47: Herbal and Dietary Supplemental Therapy
Chapter 48: Substance Abuse
, ANS: B a. Federal Food, Drug, and Cosmetic Act (1938)
First published in 1983, Drug Interaction Facts is the most comprehensive book available on b. Durham Humphrey Amendment (1952)
drug interactions. In addition to monographs listing various aspects of drug interactions, this c. Controlled Substances Act (1970)
information is reviewed and updated by an internationally renowned group of physicians and d. Kefauver Harris Drug Amendment (1962)
pharmacists with clinical and scientific expertise.
ANS: A
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3 The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
NAT:NCLEXClient NeedsCategory: Physiological Integrity of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure
TOP:NursingProcess Step: Assessment CON: Safety | Patient Education | Clinical Judgment drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used
safely without medical supervision and restricts their sale to prescription by a licensed
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section practitioner. The Controlled Substances Act addresses only controlled substances and their
of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug? categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
a. Manufacturer‘s section safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
b. Brand and Generic name section before marketing them.
c. Product category section
d. Product information section DIF: Cognitive Level: Knowledge REF: p. 5 OBJ: 6
NAT:NCLEXClient NeedsCategory: Physiological Integrity
ANS: B TOP:NursingProcess Step: Assessment
A physician‘s order would include the brand and/or generic name of the drug. The alphabetic CON: Safety | Patient Education | Evidence | Health Care Law
index in the PDR would make this section the most user-friendly. Based on a physician‘s order,
manufacturer‘s information and classification information would not be known. The 7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
Manufacturer‘s section is a roster of manufacturers. The product category section lists products dependency. Under which classification does this drug fall?
subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The a. I
product information section contains reprints of the package inserts for the major products of b. II
manufacturers. c. III
d. IV
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
NAT:NCLEXClient NeedsCategory: Physiological Integrity ANS: B
TOP:NursingProcess Step: Planning CON: Safety | Patient Education | Clinical Judgment Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
5. Which online drug reference makes available to healthcare providers and the public a standard, and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead
comprehensive, up-to-date look up and downloadable resource about medicines? to low to moderate physical dependence or high psychological dependence. Schedule IV drugs
a. American Drug Index have low potential for abuse. Use may lead to limited physical or psychological dependence.
b. American Hospital Formulary
c. DailyMed DIF: Cognitive Level: Comprehension REF: p. 5 OBJ: 2
d. Physicians’ Desk Reference (PDR) NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment
TOP:NursingProcess Step: Assessment CON: Patient Education | Addiction | Pain
ANS: C
DailyMed makes available to healthcare providers and the public a standard, comprehensive, up- 8. What would the FDA do to expedite drug development and approval for an outbreak of
to-date look up and downloadable resource about medicines. The American Drug Index is not smallpox, for which there is no known treatment?
appropriate for patient use. The American Hospital Formulary is not appropriate for patient use. a. List smallpox as a health orphan disease.
The PDR is not appropriate for patient use. b. Omit the preclinical research phase.
c. Extend the clinical research phase.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 5 OBJ: 4 d. Fast track the investigational drug.
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Implementation ANS: D
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
, Once the Investigational New Drug Application has been approved, the drug can receive highest
ANS: A
priority within the agency, which is called fast tracking. A smallpox outbreak would become a Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
priority concern in the world. Orphan diseases are not researched in a priority manner. dependence liability compared with drugs in Schedule IV. Because abuse potential is low with a
Preclinical research is not omitted. Extending any phase of the research would mean a longer
Schedule V drug, a prescription may not be required. Psychological dependency is not likely
time to develop a vaccine. The FDA must ensure that all phases of the preclinical and clinical with a Schedule V drug. Schedule V drugs are classified as controlled substances.
research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 6 OBJ: 2
DIF: Cognitive Level: Knowledge REF: p. 8 OBJ: 6 NAT:NCLEXClient NeedsCategory: Physiological Integrity
NAT:NCLEXClient NeedsCategory: Safe, Effective Care Environment TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety | Patient Education
TOP:NursingProcess Step: Assessment
CON: Health Care Law | Health Care Policy | Infection | Care Coordination 12. The nurse is transcribing new orders written for a patient with a substance abuse history. Choose
the medication ordered that has the greatest risk for abuse.
9. Which statement is true about over-the-counter (OTC) drugs?
a. Lomotil
a. They are not listed in the USP NF.
b. Diazepam
b. A prescription from a healthcare provider is needed.
c. Phenobarbital
c. They are sold without a prescription.
d. Lortab
d. They are known only by their brand names.
ANS: D
ANS: C
Lortab is a Schedule III drug with a high potential for abuse but less so than drugs in Schedules I
OTC medications do not require a prescription. A variety of names, both generic and trade, can
and II. Lomotil is a Schedule V drug with a low potential for abuse compared with those in
be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription drugs
Schedule V. Diazepam is a Schedule IV drug with a low potential for abuse compared with those
require an order by a health professional who is licensed to prescribe, such as a physician, nurse
in schedule III. Phenobarbital is a Schedule IV drug with a low potential for abuse compared
practitioner, physician assistant, or dentist.
with those in Schedule III.
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2
DIF: Cognitive Level: Application REF: p. 6 OBJ: 2
NAT:NCLEXClient NeedsCategory: Physiological Integrity
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Planning CON: Patient Education
TOP:NursingProcess Step: Assessment CON: Addiction | Patient Education | Safety
10. Which is the most authoritative reference for medications that are injected?
a. Physicians’ Desk Reference MULTIPLE RESPONSE
b. Handbook on Injectable Drugs
c. DailyMed 1. An older adult experiencing shortness of breath is brought to the hospital by her daughter. While
d. Handbook of Nonprescription Drugs obtaining the medication history from the patient and her daughter, the nurse discovers that
neither has a list of the patient‘s current medications or prescriptions. All the patient has is a
ANS: B weekly pill dispenser that contains four different pills. The prescriptions are filled through the
The Handbook on Injectable Drugs is the most comprehensive reference available on the topic of local pharmacy. Which resource(s) would be appropriate to use in determining the medication
compatibility of injectable drugs. It is a collection of monographs for more than 300 injectable names and doses? (Select all that apply.)
drugs that are listed alphabetically by generic name. a. Martindale—The Complete Drug Reference
b. Physicians’ Desk Reference, Section 4
DIF: Cognitive Level: Comprehension REF: p. 4 OBJ: 3
c. Senior citizens‘ center
NAT:NCLEXClient NeedsCategory: Physiological Integrity
TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety d. Patient‘s home pharmacy
ANS: B, D
11. The nurse is administering Lomotil, a Schedule V drug. Which statement is true about this drug‘s The Physicians’ Desk Reference, Section 4, has full color images of commonly dispensed tablets
classification? and capsules. The patient‘s pharmacy would have an accurate account of all the medications the
a. Abuse potential for this drug is low. client is currently taking. Martindale—The Complete Drug Reference has written information on
b. Psychological dependency is likely. medications and would not be an appropriate resource. The senior citizens‘ center is not likely to
c. There is a high potential for abuse.
have specific patient medication information.
d. This drug is not a controlled substance.
, DIF: Cognitive Level: Application REF: p. 3 | p. 4 OBJ: 3 1. The nurse assesses hives in a patient started on a new medication. What is the nurse‘s priority
NAT:NCLEXClient NeedsCategory: Physiological Integrity action?
TOP:NursingProcess Step: Assessment a. Notify physician of allergic reaction.
CON: Care Coordination | Safety | Patient Education | Clinical Judgment b. Notify physician of idiosyncratic reaction.
c. Notify physician of potential teratogenicity.
2. The nurse planning patient teaching regarding drug names would include which statement(s)? d. Notify physician of potential tolerance.
(Select all that apply.)
a. Most drug companies place their products on the market under generic names. ANS: A
b. The official name is the name under which the drug is listed by the US Food and An allergic reaction is indicative of hypersensitivity and manifests with hives and/or urticaria,
Drug Administration (FDA). which are easily identified. An idiosyncratic reaction occurs when something unusual or
c. Brand names are easier to pronounce, spell, and remember. abnormal happens when a drug is first administered. A teratogenic reaction refers to the
d. The first letter of the generic name is not capitalized. occurrence of birth defects related to administration of the drug. Tolerance refers to the body‘s
e. The chemical name is most meaningful to the patient. requirement for increasing dosages to achieve the same effects that a lower dose once did.
ANS: B, C, D DIF: Cognitive Level: Application REF: p. 17 OBJ: 4
The official name is the name under which the drug is listed by the FDA. Brand names are easier NAT:NCLEXClient NeedsCategory: Physiological Integrity
to pronounce, spell, and remember. The first letter of the generic name is not capitalized. Most TOP:NursingProcess Step: Assessment CON: Clinical Judgment | Safety
drug companies place their products on the market under brand names instead of generic names.
The chemical name is most meaningful to the chemist. 2. The nurse administers an initial dose of a steroid to a patient with asthma. Thirty minutes after
administration, the nurse finds the patient agitated and stating that ―everyone is out to get me.‖
DIF: Cognitive Level: Application REF: p. 1 | p. 2 OBJ: 1 What is the term for this unusual reaction?
NAT:NCLEXClient NeedsCategory: Physiological Integrity a. Desired action
TOP:NursingProcess Step: Planning CON: Patient Education | Clinical Judgment | Safety b. Adverse effect
c. Idiosyncratic reaction
3. When categorizing, the nurse is aware that which drug(s) would be considered Schedule II? d. Allergic reaction
(Select all that apply.)
a. Marijuana ANS: C
b. Percodan Idiosyncratic reactions are unusual, abnormal reactions that occur when a drug is first
c. Amphetamines administered. Patients typically exhibit an overresponsiveness to a medication related to
d. Fiorinal diminished metabolism. These reactions are believed to be related to genetic enzyme
e. Flurazepam deficiencies. Desired actions are expected responses to a medication. Adverse effects are
reactions that occur in another system of the body; they are usually predictable. Allergic
ANS: B, C reactions appear after repeated medication dosages.
Schedule II drugs have a high potential for abuse, they are currently accepted in the United
States, and use may lead to severe psychological or physical dependence. Percodan and DIF: Cognitive Level: Knowledge REF: p. 18 OBJ: 4
amphetamines are considered Schedule II drugs. Marijuana is a Schedule I drug. Fiorinal is a NAT:NCLEXClient NeedsCategory: Physiological Integrity
Schedule III drug. Flurazepam is a Schedule IV drug. TOP:NursingProcess Step: Evaluation
CON: Patient Education | Clinical Judgment | Caregiving | Safety | Sensory Perception
DIF: Cognitive Level: Analysis REF: p. 5 | p. 6 OBJ: 2
NAT:NCLEXClient NeedsCategory: Physiological Integrity 3. Which is the best description of when drug interactions occur?
TOP:NursingProcess Step: Assessment CON: Addiction | Clinical Judgment | Patient Education a. On administration of toxic dosages of a drug
b. On an increase in the pharmacodynamics of bound drugs
Chapter 02: Basic Principles of Drug Action and Drug Interactions c. On the alteration of the effect of one drug by another drug
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 18th Edition d. On increase of drug excretion
ANS: C
MULTIPLE CHOICE
