, Hematology and
Coagulation
A Comprehensive Review for Board
Preparation, Certification and
Clinical Practice
Second Edition
Amer Wahed, MD
Associate Professor of Pathology and Laboratory Medicine
University of Texas McGovern Medical School at Houston
Houston, Texas
Andres Quesada, MD
Assistant Attending Memorial Sloan Kettering Cancer Center
New York, NY
Amitava Dasgupta, PhD
Professor of Pathology and Laboratory Medicine
University of Texas McGovern Medical School at Houston
Houston, Texas
,Elsevier
Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands
The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, United Kingdom
50 Hampshire Street, 5th Floor, Cambridge, MA 02139, United States
Copyright © 2020 Elsevier Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical,
including photocopying, recording, or any information storage and retrieval system, without permission in writing
from the publisher. Details on how to seek permission, further information about the Publisher’s permissions
policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright
Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than
as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our
understanding, changes in research methods, professional practices, or medical treatment may become
necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using
any information, methods, compounds, or experiments described herein. In using such information or
methods they should be mindful of their own safety and the safety of others, including parties for whom they
have a professional responsibility.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any
liability for any injury and/or damage to persons or property as a matter of products liability, negligence or
otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the
material herein.
Library of Congress Cataloging-in-Publication Data
A catalog record for this book is available from the Library of Congress
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
ISBN: 978-0-12-814964-5
For information on all Elsevier publications visit our website
at https://www.elsevier.com/books-and-journals
Publisher: Stacy Masucci
Acquisition Editor: Tari Broderick
Editorial Project Manager: Pat Gonzalez
Production Project Manager: Sreejith Viswanathan
Cover Designer: Mark Rogers
Typeset by TNQ Technologies
, This book is dedicated to my wife Tania and my sons Arub, Ayman, and Abyan.
Amer Wahed
This book is dedicated to my father Jorge Quesada, MD, and my mother Rocio
Quesada for all their love and support throughout my life.
Andres Quesada
This book is dedicated to my wife Alice.
Amitava Dasgupta
Coagulation
A Comprehensive Review for Board
Preparation, Certification and
Clinical Practice
Second Edition
Amer Wahed, MD
Associate Professor of Pathology and Laboratory Medicine
University of Texas McGovern Medical School at Houston
Houston, Texas
Andres Quesada, MD
Assistant Attending Memorial Sloan Kettering Cancer Center
New York, NY
Amitava Dasgupta, PhD
Professor of Pathology and Laboratory Medicine
University of Texas McGovern Medical School at Houston
Houston, Texas
,Elsevier
Radarweg 29, PO Box 211, 1000 AE Amsterdam, Netherlands
The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, United Kingdom
50 Hampshire Street, 5th Floor, Cambridge, MA 02139, United States
Copyright © 2020 Elsevier Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical,
including photocopying, recording, or any information storage and retrieval system, without permission in writing
from the publisher. Details on how to seek permission, further information about the Publisher’s permissions
policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright
Licensing Agency, can be found at our website: www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than
as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our
understanding, changes in research methods, professional practices, or medical treatment may become
necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using
any information, methods, compounds, or experiments described herein. In using such information or
methods they should be mindful of their own safety and the safety of others, including parties for whom they
have a professional responsibility.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any
liability for any injury and/or damage to persons or property as a matter of products liability, negligence or
otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the
material herein.
Library of Congress Cataloging-in-Publication Data
A catalog record for this book is available from the Library of Congress
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
ISBN: 978-0-12-814964-5
For information on all Elsevier publications visit our website
at https://www.elsevier.com/books-and-journals
Publisher: Stacy Masucci
Acquisition Editor: Tari Broderick
Editorial Project Manager: Pat Gonzalez
Production Project Manager: Sreejith Viswanathan
Cover Designer: Mark Rogers
Typeset by TNQ Technologies
, This book is dedicated to my wife Tania and my sons Arub, Ayman, and Abyan.
Amer Wahed
This book is dedicated to my father Jorge Quesada, MD, and my mother Rocio
Quesada for all their love and support throughout my life.
Andres Quesada
This book is dedicated to my wife Alice.
Amitava Dasgupta
