,Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL
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PRACTICE
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1. The characteristic, localized cardinal signs of acute inflammation include:
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A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by
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momentary vasoconstriction followed by vasodilation that causes localized:
l l l l l l l l
A) bleeding.
B) congestion.
C) pale skin. l
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of
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leukocytes into the area. Which of the following cells arrives early in great
l l l l l l l l l l l l l
numbers?
l
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial
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step in the process?
l l l l
A) Engulfment
B) Intracellular killing l
C) Antigen margination l
,D) Recognition and adherence l l
5. Which of the following mediators of inflammation causes increased capillary
l l l l l l l l l
permeability and pain?
l l l
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide l
6. Inflammatory exudates are a combination of several types. Which of the
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following exudates is composed of enmeshed necrotic cells?
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A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset
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of inflammation and includes:
l l l l
A) fever and lethargy.
l l
B) decreased C-reactive protein. l l
C) positive nitrogen balance. l l
D) low erythrocyte sedimentation rate.
l l l
8. In contrast to acute inflammation, chronic inflammation is characterized by
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which of the following phenomena?
l l l l l
A) Profuse fibrinous exudation l l
B) A shift to the left of granulocytes
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C) Metabolic and respiratory alkalosis l l l
D) Lymphocytosis and activated macrophages l l l
, 9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood
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lead to the release of endogenous pyrogens that:
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A) stabilize thermal control in the brain.
l l l l l
B) produce leukocytosis and anorexia.
l l l
C) block viral replication in cells.
l l l l
D) inhibit prostaglandin release.
l l
10 An older adult patient has just sheared the skin on her elbow while attempted
l l l l l l l l l l l l l
. to boost herself up in bed, an event that has precipitated acute inflammation in
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the region surrounding the wound. Which of the following events will occur
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during the vascular stage of the patients inflammation?
l l l l l l l l
A) Outpouring of exudate into interstitial spaces l l l l l
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium l l l l l
D) Phagocytosis of cellular debris l l l
11 Which of the following individuals most likely has the highest risk of
l l l l l l l l l l l
. experiencing chronic inflammation? l l
A) A patient who has recently been diagnosed with type 2 diabetes
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B) A patient who is a carrier of an antibiotic-resistant organism
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C) A patient who is taking oral antibiotics for an upper respiratory infection
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D) A patient who is morbidly obese and who has a sedentary lifestyle
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12 Which of the following core body temperatures is within normal range?
l l l l l l l l l l
.
A) 35.9C (96.6F) l
B) 38.0C (100.4F) l
C) 35.5C (95.9F) l
D) 37.3C (99.1F) l
l l l l l l
PRACTICE
l
1. The characteristic, localized cardinal signs of acute inflammation include:
l l l l l l l l
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by
l l l l l l l l l
momentary vasoconstriction followed by vasodilation that causes localized:
l l l l l l l l
A) bleeding.
B) congestion.
C) pale skin. l
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of
l l l l l l l l l l l
leukocytes into the area. Which of the following cells arrives early in great
l l l l l l l l l l l l l
numbers?
l
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial
l l l l l l l l l l
step in the process?
l l l l
A) Engulfment
B) Intracellular killing l
C) Antigen margination l
,D) Recognition and adherence l l
5. Which of the following mediators of inflammation causes increased capillary
l l l l l l l l l
permeability and pain?
l l l
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide l
6. Inflammatory exudates are a combination of several types. Which of the
l l l l l l l l l l
following exudates is composed of enmeshed necrotic cells?
l l l l l l l l
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset
l l l l l l l l l l
of inflammation and includes:
l l l l
A) fever and lethargy.
l l
B) decreased C-reactive protein. l l
C) positive nitrogen balance. l l
D) low erythrocyte sedimentation rate.
l l l
8. In contrast to acute inflammation, chronic inflammation is characterized by
l l l l l l l l l
which of the following phenomena?
l l l l l
A) Profuse fibrinous exudation l l
B) A shift to the left of granulocytes
l l l l l l
C) Metabolic and respiratory alkalosis l l l
D) Lymphocytosis and activated macrophages l l l
, 9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood
l l l l l l l l l l
lead to the release of endogenous pyrogens that:
l l l l l l l l
A) stabilize thermal control in the brain.
l l l l l
B) produce leukocytosis and anorexia.
l l l
C) block viral replication in cells.
l l l l
D) inhibit prostaglandin release.
l l
10 An older adult patient has just sheared the skin on her elbow while attempted
l l l l l l l l l l l l l
. to boost herself up in bed, an event that has precipitated acute inflammation in
l l l l l l l l l l l l l
the region surrounding the wound. Which of the following events will occur
l l l l l l l l l l l l
during the vascular stage of the patients inflammation?
l l l l l l l l
A) Outpouring of exudate into interstitial spaces l l l l l
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium l l l l l
D) Phagocytosis of cellular debris l l l
11 Which of the following individuals most likely has the highest risk of
l l l l l l l l l l l
. experiencing chronic inflammation? l l
A) A patient who has recently been diagnosed with type 2 diabetes
l l l l l l l l l l
B) A patient who is a carrier of an antibiotic-resistant organism
l l l l l l l l l
C) A patient who is taking oral antibiotics for an upper respiratory infection
l l l l l l l l l l l
D) A patient who is morbidly obese and who has a sedentary lifestyle
l l l l l l l l l l l
12 Which of the following core body temperatures is within normal range?
l l l l l l l l l l
.
A) 35.9C (96.6F) l
B) 38.0C (100.4F) l
C) 35.5C (95.9F) l
D) 37.3C (99.1F) l