Pharmacotherapeutics for Advanced
Practice Nurse Prescribers Exam Q&A
100% Solved
Nurse practitioner prescriptive authority is regulated by who? - ✔✔The State
Board of Nursing for Each State
What is the benefits of having an APRN prescriber? - ✔✔APRN's care for
patients more holistically and include patients in making decisions regarding
their care
What does clinical judgement in prescribing include? - ✔✔Factoring in the cost
of the particular
What is included in the criteria for choosing and effective drug for a disorder? -
✔✔Consulting nationally recognized guidelines for disease management
NP's thrive under the new health-care reform because of what? - ✔✔NP's have
the ability to control care cost and improve patient outcome
Nutritional intake and lab results reflect hypoalbuminemia; why is this
important for prescribers? - ✔✔The Distribution of drugs to target tissues may
be affected
1|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
,Drugs that have an significant first-pass effect what? - ✔✔they are rapidly
metabolized by the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be? - ✔✔Lungs
Medroxyprogesterone (Depo Provera) is prescribed IM to create storage
reservoir of the drug. What are storage reserviors> - ✔✔Increased the length of
time a drug is available and active
Why is Cephalexin given every 8 hours? What knowledge of the drug does the
NP know? - ✔✔Half Life
Azithromycin doing requires that the first day's doing be twice those of the
other four day; This is considered a loading does. What is a loading dose? -
✔✔Rapidly actives drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of
a therapeutic effect is the: - ✔✔Onset of action
Phenytoin required that a trough level be drawn. When and why are peak and
trough levels are done - ✔✔To determine if a d rug is in the therapeutic range
Drugs that are receptor agonists may demonstrate what property? -
✔✔Concentrations will produce an adverse effect
2|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
, Factors that affect gastric drug absorption include - ✔✔Lipid solubility of the
drug
Drugs that are receptors antagonists, such as beta-blockers, may cause what? -
✔✔An exaggerated response if abrupt discontinues
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - ✔✔Are easily absorbed if they are
nonionized
What is the combination effect when a medication is added to a regimen for a
synergistic effect? - ✔✔Greater than the sum of the effects of each drug
individually
Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow
therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
Practice Nurse Prescribers Exam Q&A
100% Solved
Nurse practitioner prescriptive authority is regulated by who? - ✔✔The State
Board of Nursing for Each State
What is the benefits of having an APRN prescriber? - ✔✔APRN's care for
patients more holistically and include patients in making decisions regarding
their care
What does clinical judgement in prescribing include? - ✔✔Factoring in the cost
of the particular
What is included in the criteria for choosing and effective drug for a disorder? -
✔✔Consulting nationally recognized guidelines for disease management
NP's thrive under the new health-care reform because of what? - ✔✔NP's have
the ability to control care cost and improve patient outcome
Nutritional intake and lab results reflect hypoalbuminemia; why is this
important for prescribers? - ✔✔The Distribution of drugs to target tissues may
be affected
1|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
,Drugs that have an significant first-pass effect what? - ✔✔they are rapidly
metabolized by the liver and may have little if any desired action
The route of excretion of a volatile drug will likely be? - ✔✔Lungs
Medroxyprogesterone (Depo Provera) is prescribed IM to create storage
reservoir of the drug. What are storage reserviors> - ✔✔Increased the length of
time a drug is available and active
Why is Cephalexin given every 8 hours? What knowledge of the drug does the
NP know? - ✔✔Half Life
Azithromycin doing requires that the first day's doing be twice those of the
other four day; This is considered a loading does. What is a loading dose? -
✔✔Rapidly actives drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of
a therapeutic effect is the: - ✔✔Onset of action
Phenytoin required that a trough level be drawn. When and why are peak and
trough levels are done - ✔✔To determine if a d rug is in the therapeutic range
Drugs that are receptor agonists may demonstrate what property? -
✔✔Concentrations will produce an adverse effect
2|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
, Factors that affect gastric drug absorption include - ✔✔Lipid solubility of the
drug
Drugs that are receptors antagonists, such as beta-blockers, may cause what? -
✔✔An exaggerated response if abrupt discontinues
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - ✔✔Are easily absorbed if they are
nonionized
What is the combination effect when a medication is added to a regimen for a
synergistic effect? - ✔✔Greater than the sum of the effects of each drug
individually
Which of the following statements about bioavailability is true?
1) Bioavailability issues are especially important for drugs with narrow
therapeutic
ranges or sustained-release mechanisms.
2) brands of a drug have the same bioavailability.
3|Page
©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025.
