NURS 660 PSYCHOPHARM EXAM 1 AND 2 LATEST VERSION WITH COMPLETE
QUESTIONS AND COMPREHENSIVE ANSWERS WITH EXPLANATION ALREADY
GRADED A+
PSYCHOPHARM EXAM 2
1. Tolerance that occurs after one or two administrations of a drug is called
A. acute tolerance.
B. cross tolerance.
C. mithridatism.
D. tachyphylaxis.
E. both A. and D.
D. tachyphylaxis.
2. Pharmacodynamic tolerance is also known as
A. cellular tolerance.
B. homeostasis.
C. metabolic tolerance.
D. physiological tolerance.
E. both A. and D.
E. both A. and D. (cellular tolerance and physiological tolerance)
3. When tolerance for one drug diminishes the effect of another related drug, this is called
A. tolerance.
B. acute tolerance.
C. tachyphylaxis.
D. behavioral tolerance.
E. cross tolerance.
E. cross tolerance.
4. Enzyme induction
A. is important in the development of pharmacokinetic tolerance.
B. is caused by an enzyme blocker like disulfiram.
C. slows the metabolism in younger members of a species.
D. accounts for the different levels of an enzyme in different species.
E. is a major cause of accidental drug overdose.
A. is important in the development of pharmacokinetic tolerance.
5. Pharmacokinetic tolerance is also called
A. acute tolerance.
B. behavioral tolerance.
,C. cross tolerance.
D. dispositional tolerance.
E. cellular tolerance.
D. dispositional tolerance.
6. Enzyme induction is responsible for which type of tolerance?
A. acute tolerance.
B. pharmacokinetic tolerance.
C. pharmacodynamic tolerance.
D. behavioral tolerance.
E. none of the above. Enzyme levels are not responsible for any kind of tolerance
B. pharmacokinetic tolerance.
7. Which of the following defines tolerance?
A. a decrease in the effectiveness of a drug resulting from repeated administrations.
B. a decrease in the potency of a drug resulting from repeated administrations.
C. the necessity to increase the dose of a drug to achieve the same effect after repeated
administrations.
D. a shift to the right of the DRC resulting from repeated administrations.
E. all of the above.
E. all of the above.
8. Tolerance develops to different effects at different rates. This means that
A. tolerance cannot be studied scientifically.
B. we cannot predict when tolerance will occur.
C. there must be more than one mechanism of tolerance.
D. many overdoses can be attributed to the sudden loss of tolerance.
E. some people develop tolerance to a drug faster than others
C. there must be more than one mechanism of tolerance.
9. Tolerance can develop to the effects of a drug during a single administration. This is
referred to as
A. acute tolerance.
B. cross tolerance.
C. Mithridatism.
D. tachyphylaxis.
E. both A. and D
A. acute tolerance.
10. When a drug effect is greater at a specific blood level when the concentration in the
blood is rising compared to at the same blood level when the concentration in the blood is
falling, this is called
A. acute tolerance.
,B. cross tolerance.
C. metabolic tolerance.
D. behavioral tolerance.
E. none of the above. Tolerance cannot develop that quickly.
A. acute tolerance.
11. Tolerance to the anorexic effects of amphetamine will develop in rats
A. whenever the drug is repeatedly administered.
B. whenever the drug is repeatedly administered to hungry animals.
C. whenever the drug is repeatedly administered to satiated rats.
D. whenever the drug is repeatedly administered to hungry rats in the presence of food.
E. whenever the drug is repeatedly administered to hungry rats in the absence of food
D. whenever the drug is repeatedly administered to hungry rats in the presence of food.
12. Tolerance that develops as a result of learning to compensate for the effect of a drug is
called
A. cross tolerance.
B. behavioral tolerance.
C. metabolic tolerance.
D. physiological tolerance.
E. acute tolerance.
B. behavioral tolerance.
13. When physiological changes occur in response to the discontinuation of a repeatedly
administered drug, this indicates a state of
A. acute tolerance.
B. behavioral tolerance.
C. dependence.
D. habituation.
E. none of the above
C. dependence.
14. Physiological changes that occur as a result of discontinuation of a repeatedly
administered drug are called
A. withdrawal symptoms.
B. physical or physiological dependence.
C. dependence.
D. abstinence disruption.
E. all of the above.
A. withdrawal symptoms.
15. The existence of conditioned compensatory responses can explain
A. withdrawal.
, B. tolerance.
C. dissociation.
D. homeostasis.
E. both A. and B.
E. both A. and B. (withdrawal and tolerance)
16. When Siegel demonstrated that tolerance developed to repeated injections of morphine
in the same environment, but that the tolerance disappeared when the injection was later
given in a different environment, he demonstrated the existence of
A. metabolic tolerance.
B. behavioral tolerance.
C. physiological tolerance.
D. a non-generalization effect.
E. tolerance neglect.
B. behavioral tolerance.
17. Which of the following is not found at a synapse?
A. axon hillock.
B. vesicles.
C. cleft.
D. receptor sites.
E. transmitter.
A. axon hillock.
18. If a neurotransmitter has the effect of depolarizing the membrane at a synapse, this
may be referred to as
A. excitation.
B. EPSP.
C. inhibition.
D. IPSP.
E. both A. and B
E. both A. and B (excitation and EPSP)
19. Depolarization is when
A. the resting potential moves closer to firing threshold.
B. the resting potential moves further from firing threshold.
C. the cell membrane becomes more excited.
D. the cell membrane becomes less excited.
E. an action potential occurs.
A. the resting potential moves closer to firing threshold.
20. In the spinal cord
A. sensory nerves enter from the dorsal side.
QUESTIONS AND COMPREHENSIVE ANSWERS WITH EXPLANATION ALREADY
GRADED A+
PSYCHOPHARM EXAM 2
1. Tolerance that occurs after one or two administrations of a drug is called
A. acute tolerance.
B. cross tolerance.
C. mithridatism.
D. tachyphylaxis.
E. both A. and D.
D. tachyphylaxis.
2. Pharmacodynamic tolerance is also known as
A. cellular tolerance.
B. homeostasis.
C. metabolic tolerance.
D. physiological tolerance.
E. both A. and D.
E. both A. and D. (cellular tolerance and physiological tolerance)
3. When tolerance for one drug diminishes the effect of another related drug, this is called
A. tolerance.
B. acute tolerance.
C. tachyphylaxis.
D. behavioral tolerance.
E. cross tolerance.
E. cross tolerance.
4. Enzyme induction
A. is important in the development of pharmacokinetic tolerance.
B. is caused by an enzyme blocker like disulfiram.
C. slows the metabolism in younger members of a species.
D. accounts for the different levels of an enzyme in different species.
E. is a major cause of accidental drug overdose.
A. is important in the development of pharmacokinetic tolerance.
5. Pharmacokinetic tolerance is also called
A. acute tolerance.
B. behavioral tolerance.
,C. cross tolerance.
D. dispositional tolerance.
E. cellular tolerance.
D. dispositional tolerance.
6. Enzyme induction is responsible for which type of tolerance?
A. acute tolerance.
B. pharmacokinetic tolerance.
C. pharmacodynamic tolerance.
D. behavioral tolerance.
E. none of the above. Enzyme levels are not responsible for any kind of tolerance
B. pharmacokinetic tolerance.
7. Which of the following defines tolerance?
A. a decrease in the effectiveness of a drug resulting from repeated administrations.
B. a decrease in the potency of a drug resulting from repeated administrations.
C. the necessity to increase the dose of a drug to achieve the same effect after repeated
administrations.
D. a shift to the right of the DRC resulting from repeated administrations.
E. all of the above.
E. all of the above.
8. Tolerance develops to different effects at different rates. This means that
A. tolerance cannot be studied scientifically.
B. we cannot predict when tolerance will occur.
C. there must be more than one mechanism of tolerance.
D. many overdoses can be attributed to the sudden loss of tolerance.
E. some people develop tolerance to a drug faster than others
C. there must be more than one mechanism of tolerance.
9. Tolerance can develop to the effects of a drug during a single administration. This is
referred to as
A. acute tolerance.
B. cross tolerance.
C. Mithridatism.
D. tachyphylaxis.
E. both A. and D
A. acute tolerance.
10. When a drug effect is greater at a specific blood level when the concentration in the
blood is rising compared to at the same blood level when the concentration in the blood is
falling, this is called
A. acute tolerance.
,B. cross tolerance.
C. metabolic tolerance.
D. behavioral tolerance.
E. none of the above. Tolerance cannot develop that quickly.
A. acute tolerance.
11. Tolerance to the anorexic effects of amphetamine will develop in rats
A. whenever the drug is repeatedly administered.
B. whenever the drug is repeatedly administered to hungry animals.
C. whenever the drug is repeatedly administered to satiated rats.
D. whenever the drug is repeatedly administered to hungry rats in the presence of food.
E. whenever the drug is repeatedly administered to hungry rats in the absence of food
D. whenever the drug is repeatedly administered to hungry rats in the presence of food.
12. Tolerance that develops as a result of learning to compensate for the effect of a drug is
called
A. cross tolerance.
B. behavioral tolerance.
C. metabolic tolerance.
D. physiological tolerance.
E. acute tolerance.
B. behavioral tolerance.
13. When physiological changes occur in response to the discontinuation of a repeatedly
administered drug, this indicates a state of
A. acute tolerance.
B. behavioral tolerance.
C. dependence.
D. habituation.
E. none of the above
C. dependence.
14. Physiological changes that occur as a result of discontinuation of a repeatedly
administered drug are called
A. withdrawal symptoms.
B. physical or physiological dependence.
C. dependence.
D. abstinence disruption.
E. all of the above.
A. withdrawal symptoms.
15. The existence of conditioned compensatory responses can explain
A. withdrawal.
, B. tolerance.
C. dissociation.
D. homeostasis.
E. both A. and B.
E. both A. and B. (withdrawal and tolerance)
16. When Siegel demonstrated that tolerance developed to repeated injections of morphine
in the same environment, but that the tolerance disappeared when the injection was later
given in a different environment, he demonstrated the existence of
A. metabolic tolerance.
B. behavioral tolerance.
C. physiological tolerance.
D. a non-generalization effect.
E. tolerance neglect.
B. behavioral tolerance.
17. Which of the following is not found at a synapse?
A. axon hillock.
B. vesicles.
C. cleft.
D. receptor sites.
E. transmitter.
A. axon hillock.
18. If a neurotransmitter has the effect of depolarizing the membrane at a synapse, this
may be referred to as
A. excitation.
B. EPSP.
C. inhibition.
D. IPSP.
E. both A. and B
E. both A. and B (excitation and EPSP)
19. Depolarization is when
A. the resting potential moves closer to firing threshold.
B. the resting potential moves further from firing threshold.
C. the cell membrane becomes more excited.
D. the cell membrane becomes less excited.
E. an action potential occurs.
A. the resting potential moves closer to firing threshold.
20. In the spinal cord
A. sensory nerves enter from the dorsal side.
