NURS 660 EXAM 3 QUESTIONS WITH FULLY SOLVED ANSWERS.

NURS 660 EXAM 3 QUESTIONS WITH FULLY SOLVED
ANSWERS.

1) What is the medication that is the antidote for alprazolam? -- Answer ✔✔ flumazenil
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2) What is the MOA of pregabalin that makes it alleviate pain for people with
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fibromyalgia or chronic fatigue? -- Answer ✔✔ binds to the alpha 2 delta sub-units of
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voltage sensitive calcium channels
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3) What is an antagonist of caffeine -- Answer ✔✔ adenosine
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4) Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively
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worrying, increased arousal, increased tiredness and irritability. What is the primary
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and least likely diagnosis? -- Answer ✔✔ GAD; Panic Disorder
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5) Somebody w/ anxiety worries about having a panic attack, in addition has mood
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changes to avoid things in order to not have a panic attack. -- Answer ✔✔ Panic
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disorder

6) A woman was raped, and continues to have fear of opposite sex on her way to
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parking garage. Which two areas of the brain are involved? -- Answer ✔✔ amygdala
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and hippocampus
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7) MOA of modafinil (Provigil). How does it promote normal wakefulness -- Answer
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✔✔ histamine, NE at alpha adrenergic receptor sites, dopamine at D2 receptors
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8) What is the MOA of eszopiclone? What receptors does it act on? -- Answer ✔✔
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Binds to GABA receptors to increase GABA to increase sleepiness
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9) Which would be the first line appropriate pharmacological agent for PTSD? --
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Answer ✔✔ Paroxetine t t

, 10) What mediation is used to alleviate to help cognitive pain and physical symptoms in
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fibromyalgia? -- Answer ✔✔ Milnacipran (Savella) t t t t t




11) With the difficulty breathing is related hypothetically to the activation of what area
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of the brain? -- Answer ✔✔ parabrachial nucleolus
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12) What medications are good for falling asleep "sleep induction" and are not addictive?
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t-- Answer ✔✔ Suvorexant (Belsmora)
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13) Know the MOA of buspirone. Which receptor does it primarily act upon? -- Answer
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t✔✔ serotonin 1a 5HT1A partial agonist
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14) How does melatonin improve sleep? What receptors does it act on? Agonist or
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antagonist? -- Answer ✔✔ Secreted by the pineal gland to attach to receptors in thet t t t t t t t t t t t t t t




suprachiasmic nucleus to regulate the circadian rhythm; agonist t t t t t t t




15) Current dx of generalized anxiety disorder (GAD), difficulty concentrating as well as
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tproblems falling asleep. She gets very angry over basic things and is very moody in
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general, excessive stressful reactions, concentrate, irritability. What is going on in
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her brain? -- Answer ✔✔ a. Dysfunction of amygdale and CTSC (serotonin/nor-
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epinephrine)

16) Pt is coming in for detox with a long hx of alcohol abuse, HTN, and cirrhosis. He
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reports 12 beers daily for weeks. Has w/d seizures when he tries to stop drinking on
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his own. So he has elevated AST, LFT....what agent would you choose to detox him?
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-- Answer ✔✔ lorazepam
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17) Someone comes in with chronic hepatitis, also has chronic neuropathic pain. What
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medication would you AVOID prescribing to this patient and why? -- Answer ✔✔ t t t t t t t t t t t t t




Cymbalta; elevates LFTs t t




18) Benzodiazepine patient education -- Answer ✔✔ Avoid ETOH may cause dizziness, t t t t t t t t t t t




may slow heart rate, avoid sedating antihistamines
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