Questions and Answers 100% Pass
In Negative Feedback control systems - ✔✔The value of the controlled variable
fluctuates around a narrow range of set-point value
The concept of homeostasis is best defined as - ✔✔The tendency of organisms to
maintain a constant internal milieu
Blood glucose concentrations are regulated by the hormones insulin and glucagon.
When the blood glucose levels increase after eating a carbohydrate-rich meal, insulin
secretion increases and causes blood glucose to decrease towards set point
concentrations by stimulating the uptake of glucose into tissues (Such as liver/skeletal
muscle). In terminology of control systems which of the following statements is correct?
- ✔✔Glucose concentrations represents the "regulated variable", insulin the "Pathway"
to the effector, and the tissues the "effectors'"
An example of negative feedback regulation at the cellular level is the rhythmic
expression of clock genes in the clock cells. Here transcription and translation of the Per
gene into the PER proteins cycles with a rhythm of about 24 hours. Which component of
this loop is the controlled variable. - ✔✔PER protein concentration
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, Which of the following best represents the distribution of ions in the ECF and ICF of
animals? - ✔✔Na+ High in the ECF, K+High in the ICF, A- (anions) High in the ICF
According to Fick's equation the diffusion rate of solutes through a cell membrane
increases with - ✔✔Increased concentration gradient of the solute. Greater Permeability
of the membrane for the solute. High lipid solubility of the solute.
A mammalian cell membrane composed of 75% phospholipids and 25% proteins is
likely to: - ✔✔Be found in cells that associate themselves with the axons of neurons to
"electrically" insulate them from the ECF
Based on the Nernst equation the equilibrium potentials across the neuron membranes
results in values of +60mv for Na+ AND -90mv for K+. The difference in sign of voltage
(positive versus negative) result from: - ✔✔The opposite concentration gradient for Na+
and K+ (check this one)
The principle cause of depolarization of a nerve cell is - ✔✔An increase in membrane
permeability for Na+
Action potential generally originate at a location called axon hillock because - ✔✔The
hillock contains the highest number of voltage-gated K+ Channels. The hillock has the
highest number of voltage-gated Na+ channels.
The absolute refractory period of a neuron - ✔✔Is caused by Na+ channels being closed,
and no action potential can occur because these channels are inactivated
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