TEST BANK FOR:
Fundamentals of Molecular Virology
2nd Edition
by Nicholas H. Acheson Latest Update.
, 1. WHICH OF THE NEXT TERMS DESCRIBES THE PROTEIN SHELL THAT SURROUNDS THE VIRAL
GENOME?
a) CAPSID
b) ENVELOPE
c) MATRIX
d) VIRION
e) CAPSOME
RE ANS :: A
2) WHICH OF THE NEXT WOULD NOT BE A NUCLEIC ACID FORM FOUND IN A VIRAL GENOME?
a) DSDNA
b) SSDNA
c) DSRNA
d) SSRNA
e) AN RNA:DNA
HYBRID ANS :: E
3) WHICH OF THE NEXT IS AN ENZYME THAT MOST RNA VIRUSES ENCODE IN THEIR GENOME?
a) DNA-DEPENDENT-RNA-POLYMERASE
b) RNA-DEPENDENT-RNA-POLYMERASE
c) DNA-DEPENDENT-DNA-POLYMERASE
d) DNA-DEPENDENT-RNA-POLYMERASE
e) RNA-DEPENDENT-PROTEIN-
SYNTHETASE ANS :: B
,4) VIRUSES PLAY A MAJOR ROLE IN THE ECOLOGY OF THE OCEAN BY DOING WHICH OF THE NEXT?
a) BY INFECTING PHOTOSYNTHETIC BACTERIA AND INCREASING THEIR GROWTH.
b) BY INFECTING HARMFUL BACTERIA FOUND IN THE OCEAN AND LIMITING THEIR GROWTH.
c) BY KILLING OF FISH AND PREVENTING THEM FROM BECOMING TOO PLENTIFUL.
d) BY LYSING UNICELLULAR ORGANISMS AND RELEASING CARBON AND OXYGEN BACK INTO THE OCEAN.
e) ALL OF THE ABOVE STATEMENTS ARE CORRECT.
ANS :: D
5) IF YOU WANTED TO SHOW THAT AN INFECTIOUS AGENT IS A VIRUS, WHAT EXPERIMENT COULD YOU DO?
a) SHOW THAT THE AGENT CAN BE SEEN UNDER A LIGHT MICROSCOPE.
b) SHOW THAT AGENT CONTAINS A LIPID MEMBRANE.
c) SHOW THAT THE AGENT CAN FORM SINGLE COLONIES ON AN AGAR PLATE.
d) SHOW THAT THE AGENT CAN BE DILUTED AND CAN STILL CAUSE DISEASE IN AN ANIMAL.
e) SHOW THAT THE AGENT CAN PASS THROUGH A PORCELAIN FILTER AND IS STILL INFECTIOUS.
ANS :: E
6) WHAT DOES THE WORD “VIRUS” MEAN IN LATIN?
a) INFECTIOUS AGENT
b) LIQUID
c) POISON
d) DEATH
e) DISEAS
E ANS :: C
7) THE WORD “PHAGE” IS A SHORTENED VERSION OF THE NAME OF A VIRUS THAT CAN INFECT
WHICH TYPE OF ORGANISM?
a) BACTERIAL CELL
b) HUMAN CELL
c) EUKARYOTIC CELL
d) PLANT CELL
e) INSET
CELL ANS ::
A
, 8) THE STUDY OF WHICH GROUP OF VIRUSES LED TO THE DISCOVERY OF CELLULAR GENES THAT CAN
PROMOTER CANCER IN ANIMAL CELLS?
a) PAPILLOMAVIRUSES
b) RETROVIRUSES
c) ADNEOVIRUSES
d) POLYOMAVIRUSES
e) PICORNAVIRU
SES ANS :: B
9) ONCE DOING A PLAQUE ASSAY WITH HUMAN OR ANIMAL CELLS, A LAYER OF NUTRIENT MEDIA
MIXED WITH AGAR IS PUT ON TOP OF THE CELLS AFTER THEY HAVE BEEN INFECTED WITH THE DILUTED
VIRUS. WHAT IS THE MAJOR PURPOSE OF THIS AGAR LAYER?
a) IT HELPS TO FEED THE CELLS AS THEY GROW.
b) IT PROMOTES THE REPLICATION OF THE VIRUS.
c) IT MAKES THE INFECTED CELLS EASIER TO VISUALIZE.
d) IT LIMITS THE MOVEMENT OF VIRUS PARTICLES.
e) ALL OF THE ABOVE ARE CORRECT.
ANS :: D
10) TO START AN EXPERIMENT, YOU DO AN INFECTION BY PUTTING 0.5 ML OF A VIRUS STOCK THAT
HAS A TITER OF 6 X 107 PFU/ML ONTO A PLATE OF ANIMAL CELLS THAT CONTAINS 5 X 106 CELLS. WHAT
IS THE MULTIPLICITY OF INFECTION FOR THIS EXPERIMENT?
a) 12
b) 6
c) 5
d) 3
e) 1 ANS
:: B
11) DURING A SINGLE GROWTH CYCLE EXPERIMENT, THE TITER OF EXTRACELLULAR AND
INTRACELLULAR VIRUS DROPS IN THE FIRST HOUR. WHAT EXPLAINS THIS OBSERVATION?
a) THE VIRUS IS INACTIVATED BY ANTIBODIES IN THE MEDIUM.
b) THE VIRUS IS INACTIVATED BY CELLULAR ENZYMES.
Fundamentals of Molecular Virology
2nd Edition
by Nicholas H. Acheson Latest Update.
, 1. WHICH OF THE NEXT TERMS DESCRIBES THE PROTEIN SHELL THAT SURROUNDS THE VIRAL
GENOME?
a) CAPSID
b) ENVELOPE
c) MATRIX
d) VIRION
e) CAPSOME
RE ANS :: A
2) WHICH OF THE NEXT WOULD NOT BE A NUCLEIC ACID FORM FOUND IN A VIRAL GENOME?
a) DSDNA
b) SSDNA
c) DSRNA
d) SSRNA
e) AN RNA:DNA
HYBRID ANS :: E
3) WHICH OF THE NEXT IS AN ENZYME THAT MOST RNA VIRUSES ENCODE IN THEIR GENOME?
a) DNA-DEPENDENT-RNA-POLYMERASE
b) RNA-DEPENDENT-RNA-POLYMERASE
c) DNA-DEPENDENT-DNA-POLYMERASE
d) DNA-DEPENDENT-RNA-POLYMERASE
e) RNA-DEPENDENT-PROTEIN-
SYNTHETASE ANS :: B
,4) VIRUSES PLAY A MAJOR ROLE IN THE ECOLOGY OF THE OCEAN BY DOING WHICH OF THE NEXT?
a) BY INFECTING PHOTOSYNTHETIC BACTERIA AND INCREASING THEIR GROWTH.
b) BY INFECTING HARMFUL BACTERIA FOUND IN THE OCEAN AND LIMITING THEIR GROWTH.
c) BY KILLING OF FISH AND PREVENTING THEM FROM BECOMING TOO PLENTIFUL.
d) BY LYSING UNICELLULAR ORGANISMS AND RELEASING CARBON AND OXYGEN BACK INTO THE OCEAN.
e) ALL OF THE ABOVE STATEMENTS ARE CORRECT.
ANS :: D
5) IF YOU WANTED TO SHOW THAT AN INFECTIOUS AGENT IS A VIRUS, WHAT EXPERIMENT COULD YOU DO?
a) SHOW THAT THE AGENT CAN BE SEEN UNDER A LIGHT MICROSCOPE.
b) SHOW THAT AGENT CONTAINS A LIPID MEMBRANE.
c) SHOW THAT THE AGENT CAN FORM SINGLE COLONIES ON AN AGAR PLATE.
d) SHOW THAT THE AGENT CAN BE DILUTED AND CAN STILL CAUSE DISEASE IN AN ANIMAL.
e) SHOW THAT THE AGENT CAN PASS THROUGH A PORCELAIN FILTER AND IS STILL INFECTIOUS.
ANS :: E
6) WHAT DOES THE WORD “VIRUS” MEAN IN LATIN?
a) INFECTIOUS AGENT
b) LIQUID
c) POISON
d) DEATH
e) DISEAS
E ANS :: C
7) THE WORD “PHAGE” IS A SHORTENED VERSION OF THE NAME OF A VIRUS THAT CAN INFECT
WHICH TYPE OF ORGANISM?
a) BACTERIAL CELL
b) HUMAN CELL
c) EUKARYOTIC CELL
d) PLANT CELL
e) INSET
CELL ANS ::
A
, 8) THE STUDY OF WHICH GROUP OF VIRUSES LED TO THE DISCOVERY OF CELLULAR GENES THAT CAN
PROMOTER CANCER IN ANIMAL CELLS?
a) PAPILLOMAVIRUSES
b) RETROVIRUSES
c) ADNEOVIRUSES
d) POLYOMAVIRUSES
e) PICORNAVIRU
SES ANS :: B
9) ONCE DOING A PLAQUE ASSAY WITH HUMAN OR ANIMAL CELLS, A LAYER OF NUTRIENT MEDIA
MIXED WITH AGAR IS PUT ON TOP OF THE CELLS AFTER THEY HAVE BEEN INFECTED WITH THE DILUTED
VIRUS. WHAT IS THE MAJOR PURPOSE OF THIS AGAR LAYER?
a) IT HELPS TO FEED THE CELLS AS THEY GROW.
b) IT PROMOTES THE REPLICATION OF THE VIRUS.
c) IT MAKES THE INFECTED CELLS EASIER TO VISUALIZE.
d) IT LIMITS THE MOVEMENT OF VIRUS PARTICLES.
e) ALL OF THE ABOVE ARE CORRECT.
ANS :: D
10) TO START AN EXPERIMENT, YOU DO AN INFECTION BY PUTTING 0.5 ML OF A VIRUS STOCK THAT
HAS A TITER OF 6 X 107 PFU/ML ONTO A PLATE OF ANIMAL CELLS THAT CONTAINS 5 X 106 CELLS. WHAT
IS THE MULTIPLICITY OF INFECTION FOR THIS EXPERIMENT?
a) 12
b) 6
c) 5
d) 3
e) 1 ANS
:: B
11) DURING A SINGLE GROWTH CYCLE EXPERIMENT, THE TITER OF EXTRACELLULAR AND
INTRACELLULAR VIRUS DROPS IN THE FIRST HOUR. WHAT EXPLAINS THIS OBSERVATION?
a) THE VIRUS IS INACTIVATED BY ANTIBODIES IN THE MEDIUM.
b) THE VIRUS IS INACTIVATED BY CELLULAR ENZYMES.
