AAMC sample test un-scored -
chem/phys
*Compound 1 is used to treat HIV infection based on its ability
to act as:
A.
agonist
B.
antagonist
C. a
placebo
D. a catalyst correct answersAnswer is B.
antagonist
An antagonist blocks the biochemical function of the protein it binds to
(basically an which is what Compound 1 does - it blocks the catalytic
inhibitor) ->
activity oftowards
protease HIV its
substrate
^How many stereoisomers of Compound 1
exist?
A.
8
B.
16
C.
32
D. 64 correct answersAnswer is
C. 32
Calculate number of stereoisomers by 2^n rule, so
2^5 = 32
^Why do kidney stones form in some individuals treated with
Compound 1?
A. [Ca2+] + [C2O42-] >
Ksp
B. [Ca2+][C2O42-] >
Ksp
C. [Ca2+] + [C2O42-] <
Ksp
D. [Ca2+][C2O42-] < Ksp correct answersAnswer is B. [Ca2+]
[C2O42-] > Ksp
Kidney stones re effectively a precipitate of CaC2O4s) and precipitation
occurs
the reaction
when quotient Q exceeds Ksp (the equilibrium constant) - here
the reaction
quotient Q = [Ca2+]
[C2O42-]
The peptide bond between which two amino acid residues is leaved by HIV
protease:
A. Phe and
Ala
B. Pro and
C. Val and
Val
Ala
D. Phe and Pro correct answersAnswer is D. Phe
and Pro
, Peptide bond is cleaved between Phenylalanine on the N-side and Proline
on the C-
sid
e
Which image best illustrates the electric field lines between the inside of
an axon
the and
surrounding extracellular
solution?
A. arrows pointing right into the
extracellular
B. fluid left into the axon
arrows pointing
interior
C. arrows pointing down the axon
interior
D. arrows pointing up the axon interior correct
answersAnswer is B.
Electric field lines exit from positive and enter negative charges -
technically
negative it is more
inside the axon and positive in the
extracellular
One function of the myeline sheath
is to:
A. insulate the axon from the
surroundings
B. decrease the radius of the
axon
C. produce Schwann
cells
D. increase the capacitance of the axon correct answersAnswer is A.
insulate
from thethe axon
surroundings
Additionally, myelin sheath INCREASES RADIUS + is formed BY THE
SCHWANN
CELLS + DECREASES CAPACITANCE
Channel X transmits only the smallest substances dissolved in the
extracellular
through fluid membrane. Which substance does Channel X
the axon
transmit?
A.
proteins
B. sodium
C. potassium
ions
ions
D. chloride ions correct answersAnswer is B.
sodium ions
sodium cations are small by virtue of their positive charge and low atomic
number
look (juston periodic
at amu
table)
*What is the closest distance the electrodes used in an NCV test can be
placedinonorder
nerve a to measure the voltage change as a response to the
stimulus?
A. 0.01
m
B. 0.1
C. 1.0
m
m
D. 10 m correct answersAnswer is: B.
0.1 m
Figure 2 says the shortest duration that can be detected/resolved is 1
msec. The
distance travelled by this is 1 msec x (1 sec/1000 msec) x (100
m/sec) = 0.1 m
chem/phys
*Compound 1 is used to treat HIV infection based on its ability
to act as:
A.
agonist
B.
antagonist
C. a
placebo
D. a catalyst correct answersAnswer is B.
antagonist
An antagonist blocks the biochemical function of the protein it binds to
(basically an which is what Compound 1 does - it blocks the catalytic
inhibitor) ->
activity oftowards
protease HIV its
substrate
^How many stereoisomers of Compound 1
exist?
A.
8
B.
16
C.
32
D. 64 correct answersAnswer is
C. 32
Calculate number of stereoisomers by 2^n rule, so
2^5 = 32
^Why do kidney stones form in some individuals treated with
Compound 1?
A. [Ca2+] + [C2O42-] >
Ksp
B. [Ca2+][C2O42-] >
Ksp
C. [Ca2+] + [C2O42-] <
Ksp
D. [Ca2+][C2O42-] < Ksp correct answersAnswer is B. [Ca2+]
[C2O42-] > Ksp
Kidney stones re effectively a precipitate of CaC2O4s) and precipitation
occurs
the reaction
when quotient Q exceeds Ksp (the equilibrium constant) - here
the reaction
quotient Q = [Ca2+]
[C2O42-]
The peptide bond between which two amino acid residues is leaved by HIV
protease:
A. Phe and
Ala
B. Pro and
C. Val and
Val
Ala
D. Phe and Pro correct answersAnswer is D. Phe
and Pro
, Peptide bond is cleaved between Phenylalanine on the N-side and Proline
on the C-
sid
e
Which image best illustrates the electric field lines between the inside of
an axon
the and
surrounding extracellular
solution?
A. arrows pointing right into the
extracellular
B. fluid left into the axon
arrows pointing
interior
C. arrows pointing down the axon
interior
D. arrows pointing up the axon interior correct
answersAnswer is B.
Electric field lines exit from positive and enter negative charges -
technically
negative it is more
inside the axon and positive in the
extracellular
One function of the myeline sheath
is to:
A. insulate the axon from the
surroundings
B. decrease the radius of the
axon
C. produce Schwann
cells
D. increase the capacitance of the axon correct answersAnswer is A.
insulate
from thethe axon
surroundings
Additionally, myelin sheath INCREASES RADIUS + is formed BY THE
SCHWANN
CELLS + DECREASES CAPACITANCE
Channel X transmits only the smallest substances dissolved in the
extracellular
through fluid membrane. Which substance does Channel X
the axon
transmit?
A.
proteins
B. sodium
C. potassium
ions
ions
D. chloride ions correct answersAnswer is B.
sodium ions
sodium cations are small by virtue of their positive charge and low atomic
number
look (juston periodic
at amu
table)
*What is the closest distance the electrodes used in an NCV test can be
placedinonorder
nerve a to measure the voltage change as a response to the
stimulus?
A. 0.01
m
B. 0.1
C. 1.0
m
m
D. 10 m correct answersAnswer is: B.
0.1 m
Figure 2 says the shortest duration that can be detected/resolved is 1
msec. The
distance travelled by this is 1 msec x (1 sec/1000 msec) x (100
m/sec) = 0.1 m
