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handige samenvatting kankerbehandelingen oncologie

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handige samenvatting kankerbehandelingen oncologie

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Uploaded on
January 21, 2025
Number of pages
1
Written in
2023/2024
Type
Summary

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Behandeling kanker
1. Radiotherapie
 Uitwendige bestraling
 Inwendige bestraling

2. Chemotherapie
 Alkylerende middelen
 Antimetabolieten
 Topo-isomerase-inhibitoren
 Anti-tumorale antibiotica
 Microtubulaire inhibitoren

3. Hormonale therapie
 Hormonale therapie bij borstkanker
• Verwijdering van de organen die vrouwelijke geslachtshormen
produceren
• Anti-hormonen
• Aromatase-inhibitoren
• LHRH-analogen
• Progestativa

 Hormonale therapie bij prostaatkanker
• Verwijdering van de organen die mannelijk geslachtshormonen
produceren
• Anit-hormonen
• LHRH-analogen en LHRH-anatagonisten

4. Doelgerichte therapie
 Monoklonale antilichamen (extracellulair)

 Kinaseremmers
• Tyrosinekinaseremmers (TKI’s)
– Intracellulair, aan het intracellulaire gedeelte van de
groeifactorreceptor
• Serine/threoninekinaseremmers
– Intracellulair, verder op de pathway van enzumen en eiwitten

 Kan ingrijpen op verschillende pathway’s  zo invloed uitoefenen op
verschillende processen die nodig zijn voor de functie van de cel

5. Immunotherapie
 Vaccinatietherapie
 Cytokines
 Blokkade van immuno-checkpoints
• Waarvan PD-1 of anti PDL1-remmers onderdeel uitmaken (eindigen
ook op -mab)
 Gentherapie
• Onderscheid tussen in-vivo en ex-vivo gentherapie

6. Chirurgie
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