NURS 676 ADVANCED PHARMACOLOGY FINAL
EXAM REVIEW / QUESTIONS AND CORRECT
ANSWERS 2023/2024 GRADED A+. (UPDATED)
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy?
- ✔️CORRECT ANSWER✅-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate?
- ✔️CORRECT ANSWER✅-Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with?
- ✔️CORRECT ANSWER✅-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
- ✔️CORRECT ANSWER✅-Aldosterone antagonist
Heparin exerts its therapeutic action by what?
- ✔️CORRECT ANSWER✅-Upregulating the activity of one of the body's natural
anticoagulant molecules, antithrombin III
,What physiologic action happens when the offending drug is administered during
an anaphylactic reaction.
- ✔️CORRECT ANSWER✅-Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
- ✔️CORRECT ANSWER✅-Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension?
- ✔️CORRECT ANSWER✅-Thiazide diuretics
What is the effect of cardiac glycosides?
- ✔️CORRECT ANSWER✅-Digitalis glycosides have a negative chronotropic
effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
✔️CORRECT ANSWER✅-Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available
beta-receptor sites?
, - ✔️CORRECT ANSWER✅-Atenolol (Tenormin)
What type of action does nitrates have on the body?
- ✔️CORRECT ANSWER✅-Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for
patients with known coronary artery disease?
- ✔️CORRECT ANSWER✅-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs?
- ✔️CORRECT ANSWER✅-Depressing phase 4 depolarization and lengthening
phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease?
- ✔️CORRECT ANSWER✅-Anti-thyroid drugs.
What potentially serious side effect should a NP monitor or suspect in a patient
who has begun taking Lovastatin (Mevacor) approximately three weeks ago, and
who now presents complaining of generalized muscle aches.
- ✔️CORRECT ANSWER✅-Rhabdomyolysis.
EXAM REVIEW / QUESTIONS AND CORRECT
ANSWERS 2023/2024 GRADED A+. (UPDATED)
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy?
- ✔️CORRECT ANSWER✅-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate?
- ✔️CORRECT ANSWER✅-Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH
level with?
- ✔️CORRECT ANSWER✅-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
- ✔️CORRECT ANSWER✅-Aldosterone antagonist
Heparin exerts its therapeutic action by what?
- ✔️CORRECT ANSWER✅-Upregulating the activity of one of the body's natural
anticoagulant molecules, antithrombin III
,What physiologic action happens when the offending drug is administered during
an anaphylactic reaction.
- ✔️CORRECT ANSWER✅-Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications?
- ✔️CORRECT ANSWER✅-Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension?
- ✔️CORRECT ANSWER✅-Thiazide diuretics
What is the effect of cardiac glycosides?
- ✔️CORRECT ANSWER✅-Digitalis glycosides have a negative chronotropic
effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? -
✔️CORRECT ANSWER✅-Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available
beta-receptor sites?
, - ✔️CORRECT ANSWER✅-Atenolol (Tenormin)
What type of action does nitrates have on the body?
- ✔️CORRECT ANSWER✅-Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for
patients with known coronary artery disease?
- ✔️CORRECT ANSWER✅-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs?
- ✔️CORRECT ANSWER✅-Depressing phase 4 depolarization and lengthening
phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid
hormones and re-establish eumetabolic state in a patient with Graves' disease?
- ✔️CORRECT ANSWER✅-Anti-thyroid drugs.
What potentially serious side effect should a NP monitor or suspect in a patient
who has begun taking Lovastatin (Mevacor) approximately three weeks ago, and
who now presents complaining of generalized muscle aches.
- ✔️CORRECT ANSWER✅-Rhabdomyolysis.
