, Test Bank ki
to accompany
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Psychopharmacology, 4th Edition ki ki
Meyer • Quenzer ki ki
Chapter 1: Principles of Pharmacology ki ki ki ki
Multiple Choice ki
1. refer(s) to specific molecular changes that occur when a drug binds to a ki ki ki ki ki ki ki ki ki ki ki ki
particular target site or receptor, while
ki arethe resultingwidespread
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alterations in function.
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a. Drug action; therapeutic effects ki ki ki
b. Side effects; drug effects
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c. Therapeutic effects; side effects ki ki ki
d. Drug action; drug effects ki ki ki
Answer: d ki
Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is free
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to bind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. ki
c. bioavailability.
d. ED50.
Answer: c ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular target
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site or receptor are referred to as
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a. drug effects. ki
b. drug action. ki
c. side effects. ki
d. placebo effects. ki
Answer: b ki
Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning ki
b. Genetic variation ki
c. Drug competition ki
d. Expectation of outcome ki ki
Answer: c ki
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, 5. The administration of oxytocin has been proposed as a treatment for autism. ki ki ki ki ki ki ki ki ki ki
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administration ki ki
b. Lipid solubility ki
c. Depot binding ki
d. Drug action ki
Answer: d ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are taken ki ki ki ki ki ki
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
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a. cerebrospinal fluid ki
b. blood–brain barrier ki
c. choroid plexus ki
d. phospholipid membrane ki
Answer: b ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because ki ki ki ki ki ki ki
a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
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to general circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b ki
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. ki
b. choroid plexus. ki
c. area postrema.
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d. median eminence. ki
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