ABSITE INFLAMMATION AND CYTOKINES QUESTIONS WITH CORRECT ANSWERS 2025

ABSITE: INFLAMMATION AND CYTOKINES
QUESTIONS WITH CORRECT ANSWERS 2025
inflammationMphasesM-MCORRECTMANSWERM-injuryMleadsMtoMexposedMcollagenM---
>MendotheliumMreleasesMplt-activatingMandMtissueMfactorsM--->MpltsMbindMcollagenM---
>MreleaseMgrowthMfactorsM(i.e.MPDGF)M--->MPMNMandMmacrophageMrecruitmentM---
>MmacrophagesM(dominantMroleMinMwoundMhealing)MreleaseMimportantMGFM(PDGF)MandMcytokinesM(IL-
1,MTNF-alpha)



growthMandMactivatingMfactors:MPDGFM-MCORRECTMANSWERM-
chemotacticMandMactivatesMinflammatoryMcellsM(PMNsMandMmacrophages)M...MchemotacticMandMactivates
MfibroblastsM--

>McollagenMandMECMMproteinsM...Mangiogenesis,MepithelializationM...MchemotacticMforMsmoothMmuscleMcel
lsM...MhasMbeenMshownMtoMaccelerateMwoundMhealing



growthMandMactivatingMfactors:MEGFM-MCORRECTMANSWERM-
epidermalMGFM...MchemotacticMandMactivatesMfibrobalstsM...Mangiogenesis,Mepithelialization



growthMandMactivatingMfactors:MFGFM-MCORRECTMANSWERM-
fibroblasticMGFM...MchemotacticMandMactivatesMfibroblastsM---
>McollagenMandMECMMproteinsM...MangiogenesisMandMepithelialization



growthMandMactivatingMfactors:MPAFM-MCORRECTMANSWERM-platelet-
activatingMfactorM...MisMnotMstored,MgeneratedMbyMphospholipaseMinMendothelium,MisMaMphospholipidM...Mc
hemotacticMforMinflammatoryMcells,MincMadhesionMmolecules



growthMandMactivatingMfactors:MchemotacticMfactorsM-MCORRECTMANSWERM-
forMinflammatoryMcellsM=MPDGF,MIL8,MLTB4,MC5a,MC3,MPAFM...MforMfibroblastsM=MPDGF,MEGF,MFGF



growthMandMactivatingMfactors:MangiogenesisMfactorsM-MCORRECTMANSWERM-
PDGF,MEGF,MFGF,MIL8,Mhypoxia



growthMandMactivatingMfactors:MepithelializationMfactorsM-MCORRECTMANSWERM-PDGF,MEGF,MFGF

, growthMandMactivatingMfactors:MhowMlongMtoMPMNsMlast?M-MCORRECTMANSWERM-1-
2MdaysMinMtissuesM...M7MdaysMinMblood



growthMandMactivatingMfactors:MhowMlongMdoMplateletsMlast?M-MCORRECTMANSWERM-7-10Mdays



growthMandMactivatingMfactors:MroleMofMlymphocytesM-MCORRECTMANSWERM-
involvedMinMchronicMinflammationM(TMcells)MandMAbMproductionM(BMcells)



typeM1MhypersensitivityMreactions:Mcells/chemicalsMinvolvedM-MCORRECTMANSWERM-
eosinophils,Mbasophils,MmastMcells,Mhistamine,Mbasophils



typeM1MhypersensitivityMreactions:MmainMsourceMofMhistamineMinMbloodMvsMtissuesM-
MCORRECTMANSWERM-BasophilsMinMBloodM...MmasTMcellsMinMTissue




typeM1MhypersensitivityMreactions:MprimaryMcellM-MCORRECTMANSWERM-mastMcell



typeM1MhypersensitivityMreactions:MeosinophilsM-MCORRECTMANSWERM-
IgEMreceptorsMbindMtoMallergen,MreleaseMmajorMbasicMproteinMwhichMstimulatesMbasophilsMandMmastMcell
sMtoMreleaseMhistamine,MeosMareMincreasedMinMparasiticMinfections



typeM1MhypersensitivityMreactions:MbasophilsM-MCORRECTMANSWERM-
mainMsourceMofMhistamineMinMblood,MnotMfoundMinMtissue



typeM1MhypersensitivityMreactions:MmastMcellsM-MCORRECTMANSWERM-
primaryMcellMinMtypeM1MhypersensM....MmainMsourceMofMhistamineMinMtissues



typeM1MhypersensitivityMreactions:MhistamineM-MCORRECTMANSWERM-
vasodilation,MtissueMedema,MpostcapillaryMleakageM....MprimaryMeffectorMinMtypeM1MhypersensMrxnsM(aller
gicMrxn)



typeM1MhypersensitivityMreactions:MbradykininM-MCORRECTMANSWERM-
peripheralMvasodilation,MincreasedMpermeability,Mpain,MpulmonaryMvasoconstriction,MactivatedMbyMACE