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5.0
PH 346 - MIDTERM 22025- 2026 QUESTIONS WITH
DETAILED VERIFIED ANSWERS (100% CORRECT
ANSWERS) /ALREADY GRADED A+
Quiz: Transgenic organism
Ans: An engineered organism where we put the DNA of one organism into
another.
Quiz: C-elegans
Ans: Invertebrate - 959 total cells in whole organism (hermaphrodite) in
adults
Male: 1031 cells
Only has 302 neurons. 131 cells die each time
Genome has been mapped- all genes identified
Transparent/translucent - watch cells behave
Is a good model to study events like cell death
Quiz: Viktor Hamburger
Ans: Major discovery: Cell death in normal embryonic development:
Programmed cell death is an active process that sculpts normal
development.
Discovery was in chick
,Another major contribution: explored the earliest stages of embryonic motor
behavior - earliest movements do not require sensory input.
Quiz: Toxicology
Ans: Study of adverse effects of chemicals on biology/biological systems
Effects range from skin damage/irritation to death
Quiz: Natural origin chemicals = toxins
Ans: Ex. cobra venom
Quiz: Synthetically made bad chemical = toxicant
Ans: BPA
Quiz: Toxicity
Ans: Can occur on many different levels
Population, body, organ, functional unit, cell, organelle, molecule
Quiz: Cell death
Ans: From worm to human it is the same
CED-9 is the key regulator in programmed cell death in c. elegans
Bcl2 (mammal) is "homologous" to CED-9 (worm)
If you put human active Bcl2 gene in nematode - it prevents apoptosis
Examstudy - Stuvia US
, Apaf-1 is homologous to CED-4, if activated get apoptosis
Quiz: Role of cell death and digit development
Ans: BMP4 is a protein that can cause cell death
Gremlin is a protein that can inhibit BMP's
If BMP4 is down, you will get webbed digits
Pages 404-405 in the main book (Gilbert and Epel)
Quiz: Basic tenant of toxicology
Ans: All substances have the potential to be toxic
Quiz: Paracelsus
Ans: Father of toxicology
Said: "dose makes the poison"
Quiz: Dose response
Ans: Correlation between the amount of a drug given and its effects
Exposure routes (adult): dermal, oral, inhalation
Other routes include through cuts in the skin and the eyes
For fetal exposure: placenta is the exposure route
Quiz: Toxicant classifications
Examstudy - Stuvia US
In today's fast-paced educational landscape, students need reliable resources to excel in their studies.
5.0
PH 346 - MIDTERM 22025- 2026 QUESTIONS WITH
DETAILED VERIFIED ANSWERS (100% CORRECT
ANSWERS) /ALREADY GRADED A+
Quiz: Transgenic organism
Ans: An engineered organism where we put the DNA of one organism into
another.
Quiz: C-elegans
Ans: Invertebrate - 959 total cells in whole organism (hermaphrodite) in
adults
Male: 1031 cells
Only has 302 neurons. 131 cells die each time
Genome has been mapped- all genes identified
Transparent/translucent - watch cells behave
Is a good model to study events like cell death
Quiz: Viktor Hamburger
Ans: Major discovery: Cell death in normal embryonic development:
Programmed cell death is an active process that sculpts normal
development.
Discovery was in chick
,Another major contribution: explored the earliest stages of embryonic motor
behavior - earliest movements do not require sensory input.
Quiz: Toxicology
Ans: Study of adverse effects of chemicals on biology/biological systems
Effects range from skin damage/irritation to death
Quiz: Natural origin chemicals = toxins
Ans: Ex. cobra venom
Quiz: Synthetically made bad chemical = toxicant
Ans: BPA
Quiz: Toxicity
Ans: Can occur on many different levels
Population, body, organ, functional unit, cell, organelle, molecule
Quiz: Cell death
Ans: From worm to human it is the same
CED-9 is the key regulator in programmed cell death in c. elegans
Bcl2 (mammal) is "homologous" to CED-9 (worm)
If you put human active Bcl2 gene in nematode - it prevents apoptosis
Examstudy - Stuvia US
, Apaf-1 is homologous to CED-4, if activated get apoptosis
Quiz: Role of cell death and digit development
Ans: BMP4 is a protein that can cause cell death
Gremlin is a protein that can inhibit BMP's
If BMP4 is down, you will get webbed digits
Pages 404-405 in the main book (Gilbert and Epel)
Quiz: Basic tenant of toxicology
Ans: All substances have the potential to be toxic
Quiz: Paracelsus
Ans: Father of toxicology
Said: "dose makes the poison"
Quiz: Dose response
Ans: Correlation between the amount of a drug given and its effects
Exposure routes (adult): dermal, oral, inhalation
Other routes include through cuts in the skin and the eyes
For fetal exposure: placenta is the exposure route
Quiz: Toxicant classifications
Examstudy - Stuvia US
