APEX: Unit 4: Inhaled Anesthetics
UPDATED ACTUAL Exam Questions and
CORRECT Answers
How many fluorine atoms does Halothane, Iso, Des, and sevo have? - CORRECT ANSWER -
Halothane- 3
Iso-5--> 5 fluorine and 1 has a chlorine atom which increases potency
Des- 6---
Sevo 7
Sevo, des and Iso are considered what type of inhaled anesthetic? - CORRECT ANSWER -
Ethers
C-O-C
what gases have chiral carbons? - CORRECT ANSWER - Iso and Des
chiral means 4 different atoms connected to the carbon
How does full florination affect desflurane's PK/PD profile - CORRECT ANSWER --
decreases potency
- Increases vapor pressure
- increase resistance to biotransformation
how does the addition of a chlorine atom affect iso's chemical profile? - CORRECT
ANSWER - - increases potency
- increases blood: gas solubility
,vapor pressure is directly proportional to: - CORRECT ANSWER - temperature
increase in temp= increase in vapor pressure
when does boiling occur? - CORRECT ANSWER - when vapor pressure equals atmospheric
pressure
- boiling requires an open container
evaporation is when vapor pressure is below atmospheric pressure and the liquid turns into a gas
at a higher altitude ( lower atmospheric pressure), liquids boil at a _____________ temp -
CORRECT ANSWER - lower temp because of a lower atmospheric pressure
What does Dalton's Law state? - CORRECT ANSWER - the total pressure exerted by a
mixture of ideal gases is equal to the sum of the partial pressures of the individual gases in the
mixture
P total= P1+ P2+ P3
how does altitude affect a Desflurane vaporizer? - CORRECT ANSWER - Higher altitudes (
lower atmospheric pressure) patients may be underdosed
6%(0.06) desflurane x 760mmHg= 45.6
6% Desflurane x 620mmHg( denver 1 mile above sea level)= 37.2mmHg
What is Sevoflurane's
, Vapor pressure
Boiling point
molecular weight - CORRECT ANSWER - Vapor pressure: 150mmHg
Boiling point: 59C
molecular weight: 200g
What is Desflurane's:
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 669mmHg
Boiling point: 22C
molecular weight: 168g
What is Isoflurane's:
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 238mmHg
Boiling point: 49C
molecular weight: 185g
What is nitrous oxide's
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 38,770mmHg
Boiling point: -88C
UPDATED ACTUAL Exam Questions and
CORRECT Answers
How many fluorine atoms does Halothane, Iso, Des, and sevo have? - CORRECT ANSWER -
Halothane- 3
Iso-5--> 5 fluorine and 1 has a chlorine atom which increases potency
Des- 6---
Sevo 7
Sevo, des and Iso are considered what type of inhaled anesthetic? - CORRECT ANSWER -
Ethers
C-O-C
what gases have chiral carbons? - CORRECT ANSWER - Iso and Des
chiral means 4 different atoms connected to the carbon
How does full florination affect desflurane's PK/PD profile - CORRECT ANSWER --
decreases potency
- Increases vapor pressure
- increase resistance to biotransformation
how does the addition of a chlorine atom affect iso's chemical profile? - CORRECT
ANSWER - - increases potency
- increases blood: gas solubility
,vapor pressure is directly proportional to: - CORRECT ANSWER - temperature
increase in temp= increase in vapor pressure
when does boiling occur? - CORRECT ANSWER - when vapor pressure equals atmospheric
pressure
- boiling requires an open container
evaporation is when vapor pressure is below atmospheric pressure and the liquid turns into a gas
at a higher altitude ( lower atmospheric pressure), liquids boil at a _____________ temp -
CORRECT ANSWER - lower temp because of a lower atmospheric pressure
What does Dalton's Law state? - CORRECT ANSWER - the total pressure exerted by a
mixture of ideal gases is equal to the sum of the partial pressures of the individual gases in the
mixture
P total= P1+ P2+ P3
how does altitude affect a Desflurane vaporizer? - CORRECT ANSWER - Higher altitudes (
lower atmospheric pressure) patients may be underdosed
6%(0.06) desflurane x 760mmHg= 45.6
6% Desflurane x 620mmHg( denver 1 mile above sea level)= 37.2mmHg
What is Sevoflurane's
, Vapor pressure
Boiling point
molecular weight - CORRECT ANSWER - Vapor pressure: 150mmHg
Boiling point: 59C
molecular weight: 200g
What is Desflurane's:
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 669mmHg
Boiling point: 22C
molecular weight: 168g
What is Isoflurane's:
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 238mmHg
Boiling point: 49C
molecular weight: 185g
What is nitrous oxide's
Vapor pressure:
Boiling point:
molecular weight: - CORRECT ANSWER - Vapor pressure: 38,770mmHg
Boiling point: -88C
