Inhaled Anesthesia Agents UPDATED
ACTUAL Exam Questions and
CORRECT Answers
Which volatile agent decreases cerebral metabolic rate the most? - CORRECT ANSWER -
Isoflurane
What is the relationship between oil:solubility potency? MAC? - CORRECT ANSWER - If
the oil:gas solubility increases than potency increase. Proportional relationship.
Both oil:gas and potency have an inverse relationship with MAC
If the oil:gas solubility increase than MAC decreases.
Which of the following decrease the rate of rise of FA/FI? (three)
A. Increased alveolar concentration
B. Decreased time constant
C. increased FRC
D. Decreased fresh gas flow
E. Decreased anatomic dead space
F. Increased cardiac output. - CORRECT ANSWER - C. increased FRC
D. Decreased fresh gas flow
F. Increased cardiac output.
(decreased rate of rise = slower induction)
Which inhalation anesthetic possesses a blood-gas partition coefficient of 0.42? - CORRECT
ANSWER - Desflurane
, What is the relationship between solubility, the rate of uptake into the blood, the rate of
equilibration and the time of onset?. - CORRECT ANSWER - Low solubility → less uptake
into the blood → ↑ rate of rise → faster equilibration of FA/FI → Faster Onset
More solubility → more uptake into the blood → ↓ rate of rise → slower equilibration of FA/FI
→ slower Onset
(remember you want less uptake)
What is the relationship between the concentration of an agent inside the alveoli and the
concentration inside the blood and brain? - CORRECT ANSWER - Alveolar partial pressure ~
Blood partial pressure ~ Brain partial pressure
They are proportional to each other.
What is the relationship between the depth of anesthesia and the partial pressure of a gas in the
brain?
How does this affect your dosing of desflurane at higher elevations above sea level? -
CORRECT ANSWER - The depth of anesthesia is determined by the partial pressure of the
anesthetic agent in the brain and NOT the volumes percent!
At higher elevations, it may lead to underdosing of Desflurane because the Tech 6 vaporizers
does not compensate for external pressure changes like the conventional variable bypass
vaporizer. .
How are cerebral metabolic rate (CMRO2) and cerebral blood flow (CBF) altered by isoflurane?
- CORRECT ANSWER - A decrease in CMRO2 with an increase in CBF
Which volatile agent increases cerebrospinal fluid absorption? - CORRECT ANSWER -
Isoflurane
ACTUAL Exam Questions and
CORRECT Answers
Which volatile agent decreases cerebral metabolic rate the most? - CORRECT ANSWER -
Isoflurane
What is the relationship between oil:solubility potency? MAC? - CORRECT ANSWER - If
the oil:gas solubility increases than potency increase. Proportional relationship.
Both oil:gas and potency have an inverse relationship with MAC
If the oil:gas solubility increase than MAC decreases.
Which of the following decrease the rate of rise of FA/FI? (three)
A. Increased alveolar concentration
B. Decreased time constant
C. increased FRC
D. Decreased fresh gas flow
E. Decreased anatomic dead space
F. Increased cardiac output. - CORRECT ANSWER - C. increased FRC
D. Decreased fresh gas flow
F. Increased cardiac output.
(decreased rate of rise = slower induction)
Which inhalation anesthetic possesses a blood-gas partition coefficient of 0.42? - CORRECT
ANSWER - Desflurane
, What is the relationship between solubility, the rate of uptake into the blood, the rate of
equilibration and the time of onset?. - CORRECT ANSWER - Low solubility → less uptake
into the blood → ↑ rate of rise → faster equilibration of FA/FI → Faster Onset
More solubility → more uptake into the blood → ↓ rate of rise → slower equilibration of FA/FI
→ slower Onset
(remember you want less uptake)
What is the relationship between the concentration of an agent inside the alveoli and the
concentration inside the blood and brain? - CORRECT ANSWER - Alveolar partial pressure ~
Blood partial pressure ~ Brain partial pressure
They are proportional to each other.
What is the relationship between the depth of anesthesia and the partial pressure of a gas in the
brain?
How does this affect your dosing of desflurane at higher elevations above sea level? -
CORRECT ANSWER - The depth of anesthesia is determined by the partial pressure of the
anesthetic agent in the brain and NOT the volumes percent!
At higher elevations, it may lead to underdosing of Desflurane because the Tech 6 vaporizers
does not compensate for external pressure changes like the conventional variable bypass
vaporizer. .
How are cerebral metabolic rate (CMRO2) and cerebral blood flow (CBF) altered by isoflurane?
- CORRECT ANSWER - A decrease in CMRO2 with an increase in CBF
Which volatile agent increases cerebrospinal fluid absorption? - CORRECT ANSWER -
Isoflurane
