Advanced Pharmacology Final -
Practice Quiz Questions
A
R
U
LA
C
O
D
,Escitalopram may cause serious, potentially fatal reactions when used with _______________.
(select all that apply) - ANS Duloxetine, amitriptilyne, sertraline, St. John's Wort
Mixing two serotonin agents can cause serotonin syndrome.
A
The therapeutic effects of imipramine develop over _____________. - ANS Several weeks
R
The FDA-approved indications for fluoxetine include: (select all that apply) - ANS
Obsessive compulsive disorder, major depressive disorder, bulimia nervosa
Taking food with buspirone alters absorption. - ANS False
U
May be taken with food to minimize gastric irritation
LA
Venlafaxine is extensively metabolized on first pass through the ___________. - ANS Liver
Signs and symptoms of lithium toxicity include: (select all that apply) - ANS Slurred speech,
drowsiness
Valproate acid has FDA-approved indications for: (select all that apply) - ANS Acute mania,
C
simple and complex absence seizures, prevention of migraine headaches
Atomoxetine selectively ____________ the presynaptic reuptake of norepinephrine resulting in
a(n) ________________ attention span. - ANS Inhibits, improved
O
Phenelzine does not need to be discontinued several days before elective surgery that requires
anesthesia. - ANS False
D
Bupropion can be used for smoking cessation. - ANS True
Methylphenidate is not effective for narcoleptic patients. - ANS False
Clozapine may cause: (select all that apply) - ANS Syncope, orthostatic hypotension,
cardiac arrest
Causes bradycardia which could lead to syncope and cardiac arrest
,Administering risperidone with levodopa is contraindicated. - ANS True
It decreases the effects of levodopa
The ___________ form of ziprasidone is frequently used for control of acutely agitated patients.
- ANS Intramuscular (IM)
Anticonvulsants are frequently used as mood stabilizers for the treatment of mania and bipolar
spectrum disorders because they: - ANS Reduce synaptic kindling
A patient was started on fluoxetine for depression 3 days ago. She now complains that it
A
"doesn't help" and refuses to take it. Understanding the psychopharmacology, the nurse's best
first action is to: - ANS Discuss with the patient that these types of medications often take
several weeks before seeing the results.
R
Which of the following is a common side effect of both first- and second-generation
antipsychotic drugs? (select all that apply) - ANS Extrapyramidal side effects such as
pseudo-parkinsonism or acute dystonia, neuroleptic malignant syndrome, excessive sedation
U
A male patient who is taking the second-generation antipsychotic reports to the nurse that he
has observed a clear fluid leaking from his right nipple for the past month. The nurse's best
LA
initial intervention is: - ANS Inform the patient that this could be a side effect of the
medication
The physician discusses the appropriateness of prescribing a serotonin/norepinephrine
reuptake inhibitor (SNRI) for a patient. Which of the following medications are in this category? -
ANS Venlafaxine and duloxetine
C
A patient has been prescribed a selective serotonin reuptake inhibitor (SSRI) for depression.
The nurse should counsel the patient about which of the following possible side effects, among
others? - ANS Fever, sweating, agitation, rapid heartbeat
O
A nurse counsels a patient who has been prescribed a monoamine oxidase inhibitor (MAOI) to
treat depression to avoid foods containing tyramine. Which of the following foods should the
D
patient avoid? (select all that apply) - ANS Yogurt, tofu, pepperoni
A patient with severe kidney disease is started on lithium by a new resident. As the nurse on
duty your best initial response would be to: - ANS Contact the resident to remind him that
the client has kidney disease and lithium is contraindicated
Which of the following is generally true of medications used to treat anxiety disorders? - ANS
Just as with depression, the most common medications prescribed are serotonin reuptake
inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs).
, For which one of the following types of drugs is the consumption of grapefruit juice
contraindicated? - ANS Second-generation antipsychotics
Psychopharmaceutical agents are prescribed for individuals with substance use disorders for all
of the following reasons except: - ANS To elevate the patient's mood in a manner
comparable to the action of the misused substance
A patient has been prescribed disulfiram. The nurse would most appropriately counsel the
patient about which of the following? - ANS A toxic reaction if alcohol is consumed
When a patient is prescribed risperidone for schizoaffective disorder, the nurse must alert the
A
patient to the potential for neuroleptic malignant syndrome. Which of the following would be
accurate information to give the patient? - ANS Neuroleptic malignant syndrome is
potentially fatal. It usually occurs during the first 2 weeks after starting an antipsychotic drug or
R
increasing the dose and is characterized by high fever, muscle stiffness, paranoia, sweating,
and large changes in blood pressure.
A client with depression is taking phenelzine. The nurse advises the client to avoid consuming
U
which foods while taking the medication - ANS Yogurt
Methylphenidate is a CNS stimulant and is the drug of choice for individuals with
LA
attention-deficit/hyperactivity disorder (ADHD). The desired effects of methylphenidate may be
noted as: - ANS Increased attention span and concentration
The risk of experiencing serotonin syndrome when selective serotonin reuptake inhibitors
(SSRIs) are given with monoamine oxidase inhibitors (MAOIs) such as phenelzine. Serotonin
syndrome is best characterized in which of the following? - ANS Muscle rigidity and high
C
fever
A 19-year-old female client with depression who has been taking amitriptyline for three weeks
returns to the clinic for a follow-up. The nurse anticipates the possibility of observing which of
O
the following symptoms? - ANS Suicidal thoughts
A newly admitted client has started taking bupropion. The nurse understands which of the
D
following side effects that would indicate an overdose of the medication? - ANS Seizure
A client taking lithium carbonate started complaining of nausea, vomiting, diarrhea, drowsiness,
muscle weakness, tremor, blurred vision and ringing in the ears. The lithium serum level is 2
mEq/L. The nurse interprets this value as: - ANS Toxic level
Which of the following symptoms is a sign of mild lithium toxicity: - ANS Course tremor and
lethargy
Practice Quiz Questions
A
R
U
LA
C
O
D
,Escitalopram may cause serious, potentially fatal reactions when used with _______________.
(select all that apply) - ANS Duloxetine, amitriptilyne, sertraline, St. John's Wort
Mixing two serotonin agents can cause serotonin syndrome.
A
The therapeutic effects of imipramine develop over _____________. - ANS Several weeks
R
The FDA-approved indications for fluoxetine include: (select all that apply) - ANS
Obsessive compulsive disorder, major depressive disorder, bulimia nervosa
Taking food with buspirone alters absorption. - ANS False
U
May be taken with food to minimize gastric irritation
LA
Venlafaxine is extensively metabolized on first pass through the ___________. - ANS Liver
Signs and symptoms of lithium toxicity include: (select all that apply) - ANS Slurred speech,
drowsiness
Valproate acid has FDA-approved indications for: (select all that apply) - ANS Acute mania,
C
simple and complex absence seizures, prevention of migraine headaches
Atomoxetine selectively ____________ the presynaptic reuptake of norepinephrine resulting in
a(n) ________________ attention span. - ANS Inhibits, improved
O
Phenelzine does not need to be discontinued several days before elective surgery that requires
anesthesia. - ANS False
D
Bupropion can be used for smoking cessation. - ANS True
Methylphenidate is not effective for narcoleptic patients. - ANS False
Clozapine may cause: (select all that apply) - ANS Syncope, orthostatic hypotension,
cardiac arrest
Causes bradycardia which could lead to syncope and cardiac arrest
,Administering risperidone with levodopa is contraindicated. - ANS True
It decreases the effects of levodopa
The ___________ form of ziprasidone is frequently used for control of acutely agitated patients.
- ANS Intramuscular (IM)
Anticonvulsants are frequently used as mood stabilizers for the treatment of mania and bipolar
spectrum disorders because they: - ANS Reduce synaptic kindling
A patient was started on fluoxetine for depression 3 days ago. She now complains that it
A
"doesn't help" and refuses to take it. Understanding the psychopharmacology, the nurse's best
first action is to: - ANS Discuss with the patient that these types of medications often take
several weeks before seeing the results.
R
Which of the following is a common side effect of both first- and second-generation
antipsychotic drugs? (select all that apply) - ANS Extrapyramidal side effects such as
pseudo-parkinsonism or acute dystonia, neuroleptic malignant syndrome, excessive sedation
U
A male patient who is taking the second-generation antipsychotic reports to the nurse that he
has observed a clear fluid leaking from his right nipple for the past month. The nurse's best
LA
initial intervention is: - ANS Inform the patient that this could be a side effect of the
medication
The physician discusses the appropriateness of prescribing a serotonin/norepinephrine
reuptake inhibitor (SNRI) for a patient. Which of the following medications are in this category? -
ANS Venlafaxine and duloxetine
C
A patient has been prescribed a selective serotonin reuptake inhibitor (SSRI) for depression.
The nurse should counsel the patient about which of the following possible side effects, among
others? - ANS Fever, sweating, agitation, rapid heartbeat
O
A nurse counsels a patient who has been prescribed a monoamine oxidase inhibitor (MAOI) to
treat depression to avoid foods containing tyramine. Which of the following foods should the
D
patient avoid? (select all that apply) - ANS Yogurt, tofu, pepperoni
A patient with severe kidney disease is started on lithium by a new resident. As the nurse on
duty your best initial response would be to: - ANS Contact the resident to remind him that
the client has kidney disease and lithium is contraindicated
Which of the following is generally true of medications used to treat anxiety disorders? - ANS
Just as with depression, the most common medications prescribed are serotonin reuptake
inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs).
, For which one of the following types of drugs is the consumption of grapefruit juice
contraindicated? - ANS Second-generation antipsychotics
Psychopharmaceutical agents are prescribed for individuals with substance use disorders for all
of the following reasons except: - ANS To elevate the patient's mood in a manner
comparable to the action of the misused substance
A patient has been prescribed disulfiram. The nurse would most appropriately counsel the
patient about which of the following? - ANS A toxic reaction if alcohol is consumed
When a patient is prescribed risperidone for schizoaffective disorder, the nurse must alert the
A
patient to the potential for neuroleptic malignant syndrome. Which of the following would be
accurate information to give the patient? - ANS Neuroleptic malignant syndrome is
potentially fatal. It usually occurs during the first 2 weeks after starting an antipsychotic drug or
R
increasing the dose and is characterized by high fever, muscle stiffness, paranoia, sweating,
and large changes in blood pressure.
A client with depression is taking phenelzine. The nurse advises the client to avoid consuming
U
which foods while taking the medication - ANS Yogurt
Methylphenidate is a CNS stimulant and is the drug of choice for individuals with
LA
attention-deficit/hyperactivity disorder (ADHD). The desired effects of methylphenidate may be
noted as: - ANS Increased attention span and concentration
The risk of experiencing serotonin syndrome when selective serotonin reuptake inhibitors
(SSRIs) are given with monoamine oxidase inhibitors (MAOIs) such as phenelzine. Serotonin
syndrome is best characterized in which of the following? - ANS Muscle rigidity and high
C
fever
A 19-year-old female client with depression who has been taking amitriptyline for three weeks
returns to the clinic for a follow-up. The nurse anticipates the possibility of observing which of
O
the following symptoms? - ANS Suicidal thoughts
A newly admitted client has started taking bupropion. The nurse understands which of the
D
following side effects that would indicate an overdose of the medication? - ANS Seizure
A client taking lithium carbonate started complaining of nausea, vomiting, diarrhea, drowsiness,
muscle weakness, tremor, blurred vision and ringing in the ears. The lithium serum level is 2
mEq/L. The nurse interprets this value as: - ANS Toxic level
Which of the following symptoms is a sign of mild lithium toxicity: - ANS Course tremor and
lethargy
