Questions and Verified Answers Key
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___ ____ pathogens are more likely to produce septic shock. Name two. - Correct Answers-Gram
negative
Escherichia coli and Pseudomonas spp.
~50% of all cases are ___ ____ or ___ ___. - Correct Answers-Staphylococcus aureus
Streptococcus pneumoniae
Bacterial sepsis is most commonly ____ ____. - Correct Answers-Gram positive
BE SURE to review slide 12 of the sepsis lecture for guidance of clinical decisions. - Correct
Answers-
Begin fluid challenge as soon as ______ is recognized - Correct Answers-hypoperfusion
BEST PRACTICE STATEMENT:
Medical Emergency
Early detection: time
Treatment
Immediate treatment saves lives
Sepsis NOTES:
Most expensive hospital condition
Outcomes
High mortality
Morbidity
"Post-sepsis syndrome" - Correct Answers-
Clinical presentation - dysregulation of host response. What are the systemic signs of infection? -
Correct Answers-Fever or hypothermia
Tachycardia
, Tachypnea
Leukocytosis or leukopenia
Chills
Hyperglycemia
Myalgia
Lethargy
SIRS criteria shown on the dysregulation of host response:
Fever or hypothermia
Tachycardia
Tachypnea
Leukocytosis or leukopenia
Clinical presentation of sepsis-induced organ dysfunction. Name 7. - Correct Answers-Confusion
Oliguria
Acute kidney injury
Lactic acidosis
Pulmonary edema
Acute respiratory distress syndrome (ARDS)
Coagulopathy
Combination therapy in sepsis is for what? - Correct Answers-DOUBLE COVERAGE FOR
SPECIFICALLY FOR THE GRAM NEGATIVE ORGANISMS
Empirically use 2 agents from different class as "double coverage" for possible, multi-drug resistant
pathogens (usually Gram negative organisms).
Crystalloids (like normal saline) are suggested as initial choice of fluid resuscitation at a minimum rate
_____mL/kg within _____ hours - Correct Answers-30 mL/kg within 3 hours
Balanced crystalloids or saline is suggested