My NR 546 Week 6 Review Questions
and Complete Solutions Graded A+
Key NTM that regulates mood - Answer: Dopamine
The mesolimbic pathway (part of the dopamine pathway) which - Answer: regulates emotional
behaviors, reward, and pleasure
•Overactivation of it mesolimbic pathway causes - Answer: symptoms of addiction
Medications for SUD block - Answer: dopamine specifically in the mesolimbic pathway
Which opioid can cause respiratory depression if utilized with BZOs and can also be used during acute
coronary syndrome or refractory ischemic chest pain? - Answer: Morphine
Which opioid is an opioid agonist but more potent that morphine? - Answer: hydromorphone
Which medication is used in detoxification and maintenance of treatment of opioid and heroin addiction
by helping prevent cravings and withdrawal symptoms? - Answer: Methadone
Which medication is the preferred opioid to those who are unable to tolerate morphine or those who
have severe hepatic and renal diseases? - Answer: Fentanyl
Which medication is not longer recommended an an analgesic because it can cause seizures and
delirium? - Answer: meperidine
Which medication blocks the reuptake of serotonin and norepinephrine and can therefore cause
serotonin syndrome? - Answer: Tramadol
Which medication is an antihypertensive agent that has off-label uses for treatment of medically
supervised opioid withdrawal? - Answer: Clonidine
, Which medication is a pure antagonist used for treatment of acute opioid overdose? - Answer: Naloxone
(Narcan)
Common comorbidities of SUD include: - Answer: •anxiety disorders
•depression
•bipolar disorder
•psychotic illness
•borderline personality disorder
•antisocial personality disorder
SUD - Genetics - Answer: May impact a person's experience of a drug as pleasurable or not
May impact how long a drug remans in the body
Specific genetic factors predispose a person to alcohol dependence and tobacco use
SUD-Neuroanatomy - Answer: Mesolimbic pathway and dopamine production
SUD-Neural networks - Answer: Drugs and alcohol act directly on brain receptors leading to a release in
dopamine with fires up the reward center
SUD-Neural networks - Answer: Drugs and alcohol act directly on brain receptors leading to a release in
dopamine with fires up the reward center
Neural signaling - Answer: u\When dopamine is released in surges in response to drugs, changes in brain
circulatory can occur leading to cravings, addiction, dependence, and withdrawal
With repeated ingestion of a drug, the drug shows decreased effect. Increasing doses are required to
achieve the effects noted with the original administration. - Answer: Tolerance
State of adaptation produced with repeated administration of certain drugs so that physical symptoms
occur when the drug is discontinued abruptly. - Answer: Dependence
and Complete Solutions Graded A+
Key NTM that regulates mood - Answer: Dopamine
The mesolimbic pathway (part of the dopamine pathway) which - Answer: regulates emotional
behaviors, reward, and pleasure
•Overactivation of it mesolimbic pathway causes - Answer: symptoms of addiction
Medications for SUD block - Answer: dopamine specifically in the mesolimbic pathway
Which opioid can cause respiratory depression if utilized with BZOs and can also be used during acute
coronary syndrome or refractory ischemic chest pain? - Answer: Morphine
Which opioid is an opioid agonist but more potent that morphine? - Answer: hydromorphone
Which medication is used in detoxification and maintenance of treatment of opioid and heroin addiction
by helping prevent cravings and withdrawal symptoms? - Answer: Methadone
Which medication is the preferred opioid to those who are unable to tolerate morphine or those who
have severe hepatic and renal diseases? - Answer: Fentanyl
Which medication is not longer recommended an an analgesic because it can cause seizures and
delirium? - Answer: meperidine
Which medication blocks the reuptake of serotonin and norepinephrine and can therefore cause
serotonin syndrome? - Answer: Tramadol
Which medication is an antihypertensive agent that has off-label uses for treatment of medically
supervised opioid withdrawal? - Answer: Clonidine
, Which medication is a pure antagonist used for treatment of acute opioid overdose? - Answer: Naloxone
(Narcan)
Common comorbidities of SUD include: - Answer: •anxiety disorders
•depression
•bipolar disorder
•psychotic illness
•borderline personality disorder
•antisocial personality disorder
SUD - Genetics - Answer: May impact a person's experience of a drug as pleasurable or not
May impact how long a drug remans in the body
Specific genetic factors predispose a person to alcohol dependence and tobacco use
SUD-Neuroanatomy - Answer: Mesolimbic pathway and dopamine production
SUD-Neural networks - Answer: Drugs and alcohol act directly on brain receptors leading to a release in
dopamine with fires up the reward center
SUD-Neural networks - Answer: Drugs and alcohol act directly on brain receptors leading to a release in
dopamine with fires up the reward center
Neural signaling - Answer: u\When dopamine is released in surges in response to drugs, changes in brain
circulatory can occur leading to cravings, addiction, dependence, and withdrawal
With repeated ingestion of a drug, the drug shows decreased effect. Increasing doses are required to
achieve the effects noted with the original administration. - Answer: Tolerance
State of adaptation produced with repeated administration of certain drugs so that physical symptoms
occur when the drug is discontinued abruptly. - Answer: Dependence
