COMSAE Cramming UPDATED ACTUAL
Questions and CORRECT Answers
drug for UC/Crohns - CORRECT ANSWER - sulfasalazine
pulmonary effects of CF - CORRECT ANSWER - chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - CORRECT ANSWER - (spongy and ) trabecular
bone mass loss
Imipramine is what type of drug? - CORRECT ANSWER - TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
loratidine vs ranitidine - CORRECT ANSWER - loratidine: 2nd gen H1 blocker, doesnt
cross BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
H1 think allergies
H2 think gastric
,What organism presents as cells w RBCs inside - CORRECT ANSWER - entaemoba
histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - CORRECT
ANSWER - tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- CORRECT ANSWER - AVM arteriovenous malformation
What is a cavernous hemangioma - CORRECT ANSWER - benign tumor of liver, A/W
VHL
anti-HepB surface antibody is only present in what population - CORRECT ANSWER -
recovered or immunized
not in chronic or acute
proctalgia fugax is a form of what? - CORRECT ANSWER - levator ani syndrome
Proctalgia fugax is a form of levator syndrome (also called levator ani syndrome). Both include
spasms of muscles in the pelvic area. Proctalgia fugax is temporary, but other types of levator
syndrome can last for several days. Another major difference is the location of the pain.
fasciculus is UMN or LMN lesion? - CORRECT ANSWER - LMN
antibodies in hashimotos attacks - CORRECT ANSWER - thyroid peroxidase or
antithyroglobulin
enlarged non tender thyroid
,2 factors that influence starling curve - CORRECT ANSWER - x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia includes - CORRECT ANSWER - TCA, SNRIs anticonvulsants
what drugs block NE reuptake? - CORRECT ANSWER - TCA or SNRIs
possible complication of pagets bone disease - CORRECT ANSWER - osteocarcoma
what does Hct tell you? - CORRECT ANSWER - ratio of volume of RBCs compared to
total blood volume
Probenecid MOA ? Common risk factor? - CORRECT ANSWER - inhibits reabsoprtion of
uric acid in PCT
- also inhibits secretion of PCN
- can cause uric acid calculi
2 causes of SCID include - CORRECT ANSWER - 1.) ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
2.) (most common) mutations in the gamma chain shared by a number of interleukin receptors
(X-SCID)
lithiums effects on urination - CORRECT ANSWER - inhibits vasopression/ADH -->
increased urinary frequency —> diabetes insipidus
infertility drug that can result in multiple fetuses? MOA? Side effects? - CORRECT
ANSWER - clomiphene (clones- multiple babies)
, antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
Used to treat infertility and polycystic ovarian syndrome. may cause hot flashes, ovarian
enlargement, multiple simultaneous pregnancies and visual disturbances.
AFP levels in down syndrome? - CORRECT ANSWER - low AFP
Which GI malformation is A/W down syndrome - CORRECT ANSWER - Hirschprungs-
congenital aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - CORRECT ANSWER - thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea? - CORRECT ANSWER - azoles
Can you give beta blockers for asthma? - CORRECT ANSWER - Nope- even beta 1s can
be nonselective at higher doses
what kind of teratogenic effects are seen w ACE/ARBs - CORRECT ANSWER - fetal
renal agenesis
Questions and CORRECT Answers
drug for UC/Crohns - CORRECT ANSWER - sulfasalazine
pulmonary effects of CF - CORRECT ANSWER - chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - CORRECT ANSWER - (spongy and ) trabecular
bone mass loss
Imipramine is what type of drug? - CORRECT ANSWER - TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
loratidine vs ranitidine - CORRECT ANSWER - loratidine: 2nd gen H1 blocker, doesnt
cross BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
H1 think allergies
H2 think gastric
,What organism presents as cells w RBCs inside - CORRECT ANSWER - entaemoba
histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - CORRECT
ANSWER - tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- CORRECT ANSWER - AVM arteriovenous malformation
What is a cavernous hemangioma - CORRECT ANSWER - benign tumor of liver, A/W
VHL
anti-HepB surface antibody is only present in what population - CORRECT ANSWER -
recovered or immunized
not in chronic or acute
proctalgia fugax is a form of what? - CORRECT ANSWER - levator ani syndrome
Proctalgia fugax is a form of levator syndrome (also called levator ani syndrome). Both include
spasms of muscles in the pelvic area. Proctalgia fugax is temporary, but other types of levator
syndrome can last for several days. Another major difference is the location of the pain.
fasciculus is UMN or LMN lesion? - CORRECT ANSWER - LMN
antibodies in hashimotos attacks - CORRECT ANSWER - thyroid peroxidase or
antithyroglobulin
enlarged non tender thyroid
,2 factors that influence starling curve - CORRECT ANSWER - x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia includes - CORRECT ANSWER - TCA, SNRIs anticonvulsants
what drugs block NE reuptake? - CORRECT ANSWER - TCA or SNRIs
possible complication of pagets bone disease - CORRECT ANSWER - osteocarcoma
what does Hct tell you? - CORRECT ANSWER - ratio of volume of RBCs compared to
total blood volume
Probenecid MOA ? Common risk factor? - CORRECT ANSWER - inhibits reabsoprtion of
uric acid in PCT
- also inhibits secretion of PCN
- can cause uric acid calculi
2 causes of SCID include - CORRECT ANSWER - 1.) ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
2.) (most common) mutations in the gamma chain shared by a number of interleukin receptors
(X-SCID)
lithiums effects on urination - CORRECT ANSWER - inhibits vasopression/ADH -->
increased urinary frequency —> diabetes insipidus
infertility drug that can result in multiple fetuses? MOA? Side effects? - CORRECT
ANSWER - clomiphene (clones- multiple babies)
, antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
Used to treat infertility and polycystic ovarian syndrome. may cause hot flashes, ovarian
enlargement, multiple simultaneous pregnancies and visual disturbances.
AFP levels in down syndrome? - CORRECT ANSWER - low AFP
Which GI malformation is A/W down syndrome - CORRECT ANSWER - Hirschprungs-
congenital aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - CORRECT ANSWER - thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea? - CORRECT ANSWER - azoles
Can you give beta blockers for asthma? - CORRECT ANSWER - Nope- even beta 1s can
be nonselective at higher doses
what kind of teratogenic effects are seen w ACE/ARBs - CORRECT ANSWER - fetal
renal agenesis
