PHCH 667 : EXAM ONE QUESTIONS WITH
VERIFIED ANSWERS [ GRADED A+]
why study clinical chemistry? - ✔✔molecular indicators of health status or disease
interface between biochemistry (tests) and medicine (treatment)
what is an analyte? - ✔✔substance measured by the assay
what is a biomarker? - ✔✔characteristic that is measured/evaluated as an
indicator of normal processes
what is a specimen? - ✔✔sample used for lab analysis
©morren2024/2025.Year published 2024.
,what is a quantitative test? - ✔✔test that gives a number measurement
what is a qualitative test? - ✔✔test the gives a yes or no answer
why are stats used in clinical chemistry? - ✔✔determine which results are within
normal/reference range
if not there is cause for concern
assay paramaters: quantitative - ✔✔accuracy
precision
reference value
critical value
assay parameters: qualitative - ✔✔sensitivity
specificity
©morren2024/2025.Year published 2024.
,predictive value
accuracy
accuracy - ✔✔depends on mean and gives a range of what is normal
more desirable for large sample
precision - ✔✔depends on standard deviation and gives a range of what is normal
more important for small sample
mean - ✔✔average of values
closer a sample's mean is to true value = more accurate
standard deviation - ✔✔spread of values
lower spread = more precise
©morren2024/2025.Year published 2024.
, 68-95-99.7 rule - ✔✔1 SD away includes 68%
2 includes 95%
3 includes 99.7%
what is the most commonly used "acceptable level of significance" used in clinical
chemistry? - ✔✔95%
what is a reference range? - ✔✔range where values of 95% of the "healthy"
individuals are within (2 standard deviations)
coefficient of variation - ✔✔ratio of standard deviation to the mean
helps compare assays with different units
what is specificity and how is it calculated? - ✔✔true negative rate of the test
ability to correctly identify the "healthy"
©morren2024/2025.Year published 2024.
VERIFIED ANSWERS [ GRADED A+]
why study clinical chemistry? - ✔✔molecular indicators of health status or disease
interface between biochemistry (tests) and medicine (treatment)
what is an analyte? - ✔✔substance measured by the assay
what is a biomarker? - ✔✔characteristic that is measured/evaluated as an
indicator of normal processes
what is a specimen? - ✔✔sample used for lab analysis
©morren2024/2025.Year published 2024.
,what is a quantitative test? - ✔✔test that gives a number measurement
what is a qualitative test? - ✔✔test the gives a yes or no answer
why are stats used in clinical chemistry? - ✔✔determine which results are within
normal/reference range
if not there is cause for concern
assay paramaters: quantitative - ✔✔accuracy
precision
reference value
critical value
assay parameters: qualitative - ✔✔sensitivity
specificity
©morren2024/2025.Year published 2024.
,predictive value
accuracy
accuracy - ✔✔depends on mean and gives a range of what is normal
more desirable for large sample
precision - ✔✔depends on standard deviation and gives a range of what is normal
more important for small sample
mean - ✔✔average of values
closer a sample's mean is to true value = more accurate
standard deviation - ✔✔spread of values
lower spread = more precise
©morren2024/2025.Year published 2024.
, 68-95-99.7 rule - ✔✔1 SD away includes 68%
2 includes 95%
3 includes 99.7%
what is the most commonly used "acceptable level of significance" used in clinical
chemistry? - ✔✔95%
what is a reference range? - ✔✔range where values of 95% of the "healthy"
individuals are within (2 standard deviations)
coefficient of variation - ✔✔ratio of standard deviation to the mean
helps compare assays with different units
what is specificity and how is it calculated? - ✔✔true negative rate of the test
ability to correctly identify the "healthy"
©morren2024/2025.Year published 2024.
