CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST 2024 – 2025 ALREADY GRADED A+
Hypersensitivity Type IV - ANSWERS-No longer immediate, delayed or cell
mediated. No antibodies involved. Sensitized T cells react with antigens. Reaction
takes around 24 hours to develop following contact with antigens.
Hashimoto's Thyroiditis - ANSWERS-Autoantibodies against thyroglobulin damage
thyroid gland. Treatment - thyroid hormones.
Goodpasture's Syndrome - ANSWERS-Autoantibodies to kidney and lung
basement membrane. Treatment - corticosteroids to suppress the immune
response and plasmapheresis to remove autoantibodies; kidney dialysis may be
required.
Grave's Disease - ANSWERS-Autoantibody against receptor for thyroid stimulating
hormone (TSH). Thyroid gland is OVERSTIMULATED, resulting in hyperthyroidism
, Laboratory detection - measure TSH and T4 serum hormones. Treatment -
thyroidectomy.
Primary Immunodeficiency Disorders - ANSWERS-Congenital: present at birth
Genetic:
Spontaneous mutation or inherited
Most defects are minor or subclinical
Subdivided by cell type affected or the point at which cell maturation is blocked
Acquired primary disorders of the immune cells, such as HIV/AIDS.
Secondary Immunodeficiency Disorders - ANSWERS-Due to an exogenous agent
or condition
Severe nutritional defects, burns, chemotherapy
Not usually present at birth
Immunodeficiency not always permanent
Pathogenesis - ANSWERS-Steps in the development of the disease and how
etiological factors trigger cellular and molecular changes.