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1
JANEWAY'S IMMUNOBIOLOGY CHAPTER 1:
BASIC CONCEPTS IN IMMUNOLOGY
QUESTIONS AND CORRECT DETAILED
ANSWERS 2025-2026 (VERIFIED ANSWERS)
||ALREADY GRADED A+||NEWEST VERSION
acquired immune response ANS: The response of antigen-specific lymphocytes to
antigen, including the development of immunological memory. Adaptive immune responses
are distinct from the innate and nonadaptive phases of immunity, which are not mediated by
clonal selection of antigen-specific lymphocytes.
adaptive immunity ANS: Immunity to infection conferred by an adaptive immune
response.
adenoids ANS: Paired mucosal-associated lymphoid tissues located in the nasal cavity.
adjuvant ANS: Any substance that enhances the immune response to an antigen with
which it is mixed.
afferent lymphatic vessels ANS: Vessels of the lymphatic system that drain extracellular
fluid from the tissues and carry antigen, macrophages, and dendritic cells from sites of
infection to lymph nodes or other peripheral lymphoid organs.
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affinity maturation ANS: The increase in affinity for their specific antigen of the
antibodies produced as an adaptive immune response progresses. This phenomenon is
particularly prominent in secondary and subsequent immunizations.
antibody ANS: Each antibody molecule has a unique structure that enables it to bind
specifically to its corresponding antigen, but all antibodies have the same overall structure
and are known collectively as immunoglobulins. Antibodies are produced by differentiated B
cells (plasma cells) in response to infection or immunization, and bind to and neutralize
pathogens or prepare them for uptake and destruction by phagocytes. Are a protein.
antigen ANS: Any molecule that can bind specifically to an antibody or generate
peptide fragments that are recognized by a T-cell receptor.
antigen-binding site ANS: The site at the tip of each arm of an antibody that makes
physical contact with the antigen and binds it noncovalently. The antigen specificity of the
site is determined by its shape and the amino acids present.
antigenetic determinant ANS: That portion of an antigenic molecule that is bound by
the antigen-binding site of a given antibody or antigen receptor; it is also known as an
epitope.
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antigen-presenting cells ANS: (APC's) Highly specialized cells that can process antigens
and display their peptide fragments on the cell surface together with other, co-stimulatory,
proteins required for activating naive T cells. The main antigen-presenting cells for naive T
cells are dendritic cells, macrophages, and B cells.
antigen receptor ANS: The cell-surface receptor by which lymphocytes recognize
antigen. Each individual lymphocyte bears receptors of a single antigen specificity.
apoptosis ANS: A form of cell death common in the immune system, in which the cell
activates an internal death program. It is characterized by nuclear DNA degradation, nuclear
degeneration and condensation, and the rapid phagocytosis of cell remains. Proliferating
lymphocytes experience high rates of apoptosis during their development and during
immune responses.
allergy ANS: The state in which a symptomatic immune reaction is made to a normally
innocuous environmental antigen. It involves the interaction between the antigen and
antibody or primed T cells produced by earlier exposure to the same antigen.
antigen:antibody complexes ANS: Noncovalently associated groups of antibody
molecules bound to their specific antigen.
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[+254707240657]
1
JANEWAY'S IMMUNOBIOLOGY CHAPTER 1:
BASIC CONCEPTS IN IMMUNOLOGY
QUESTIONS AND CORRECT DETAILED
ANSWERS 2025-2026 (VERIFIED ANSWERS)
||ALREADY GRADED A+||NEWEST VERSION
acquired immune response ANS: The response of antigen-specific lymphocytes to
antigen, including the development of immunological memory. Adaptive immune responses
are distinct from the innate and nonadaptive phases of immunity, which are not mediated by
clonal selection of antigen-specific lymphocytes.
adaptive immunity ANS: Immunity to infection conferred by an adaptive immune
response.
adenoids ANS: Paired mucosal-associated lymphoid tissues located in the nasal cavity.
adjuvant ANS: Any substance that enhances the immune response to an antigen with
which it is mixed.
afferent lymphatic vessels ANS: Vessels of the lymphatic system that drain extracellular
fluid from the tissues and carry antigen, macrophages, and dendritic cells from sites of
infection to lymph nodes or other peripheral lymphoid organs.
o
o
Thank You for Choosing Us!
© 2024 TestTrackers o Resources & Updates: [Testtrackers - Stuvia US]
o Customer Support: o Your Success is Our Mission!
[+254707240657]
, Testtrackers
2
affinity maturation ANS: The increase in affinity for their specific antigen of the
antibodies produced as an adaptive immune response progresses. This phenomenon is
particularly prominent in secondary and subsequent immunizations.
antibody ANS: Each antibody molecule has a unique structure that enables it to bind
specifically to its corresponding antigen, but all antibodies have the same overall structure
and are known collectively as immunoglobulins. Antibodies are produced by differentiated B
cells (plasma cells) in response to infection or immunization, and bind to and neutralize
pathogens or prepare them for uptake and destruction by phagocytes. Are a protein.
antigen ANS: Any molecule that can bind specifically to an antibody or generate
peptide fragments that are recognized by a T-cell receptor.
antigen-binding site ANS: The site at the tip of each arm of an antibody that makes
physical contact with the antigen and binds it noncovalently. The antigen specificity of the
site is determined by its shape and the amino acids present.
antigenetic determinant ANS: That portion of an antigenic molecule that is bound by
the antigen-binding site of a given antibody or antigen receptor; it is also known as an
epitope.
o
o
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© 2024 TestTrackers o Resources & Updates: [Testtrackers - Stuvia US]
o Customer Support: o Your Success is Our Mission!
[+254707240657]
, Testtrackers
3
antigen-presenting cells ANS: (APC's) Highly specialized cells that can process antigens
and display their peptide fragments on the cell surface together with other, co-stimulatory,
proteins required for activating naive T cells. The main antigen-presenting cells for naive T
cells are dendritic cells, macrophages, and B cells.
antigen receptor ANS: The cell-surface receptor by which lymphocytes recognize
antigen. Each individual lymphocyte bears receptors of a single antigen specificity.
apoptosis ANS: A form of cell death common in the immune system, in which the cell
activates an internal death program. It is characterized by nuclear DNA degradation, nuclear
degeneration and condensation, and the rapid phagocytosis of cell remains. Proliferating
lymphocytes experience high rates of apoptosis during their development and during
immune responses.
allergy ANS: The state in which a symptomatic immune reaction is made to a normally
innocuous environmental antigen. It involves the interaction between the antigen and
antibody or primed T cells produced by earlier exposure to the same antigen.
antigen:antibody complexes ANS: Noncovalently associated groups of antibody
molecules bound to their specific antigen.
o
o
Thank You for Choosing Us!
© 2024 TestTrackers o Resources & Updates: [Testtrackers - Stuvia US]
o Customer Support: o Your Success is Our Mission!
[+254707240657]
