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COMSAE Cramming Exam Questions and Answers 100% Pass

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COMSAE Cramming Exam Questions and Answers 100% Pass drug for UC/Crohns - ANSWER -sulfasalazine pulmonary effects of CF - ANSWER -chronic bronchitis and bronchiectasis osteoporosis affects what parts of bone? - ANSWER -(spongy and ) trabecular bone mass loss Imipramine is what type of drug? - ANSWER -TCA SE: Tri-Cs convulsions coma cardiotox antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block alpha1) loratidine vs ranitidine - ANSWER -loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less sedating ranitidine: H2 receptor antagonist (like cimetidine) H1 think allergies 2 | P a g e Created by Grace Amelia © 2025, All Rights Reserved. H2 think gastric What organism presents as cells w RBCs inside - ANSWER -entaemoba histolytica which type of pneumothorax causes tracheal deviation to the contra side? - ANSWER -tension intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels - ANSWER -AVM arteriovenous malformation What is a cavernous hemangioma - ANSWER -benign tumor of liver, A/W VHL anti-HepB surface antibody is only present in what population - ANSWER -recovered or immunized not in chronic or acute proctalgia fugax is a form of what? - ANSWER -levator ani syndrome Proctalgia fugax is a form of levator syndrome (also called levator ani syndrome). Both include spasms of muscles in the pelvic area. Proctalgia fugax is temporary, but other types of levator syndrome can last for several days. Another major difference is the location of the pain. fasciculus is UMN or LMN lesion? - ANSWER -LMN antibodies in hashimotos attacks - ANSWER -thyroid peroxidase or antithyroglobulin enlarged non tender thyroid 2 factors that influence starling curve - ANSWER -x axis- preload (EDV) y axis- stroke volume or CO 3 | P a g e Created by Grace Amelia © 2025, All Rights Reserved. treatment for fibromyalgia includes - ANSWER -TCA, SNRIs anticonvulsants what drugs block NE reuptake? - ANSWER -TCA or SNRIs possible complication of pagets bone disease - ANSWER -osteocarcoma what does Hct tell you? - ANSWER -ratio of volume of RBCs compared to total blood volume Probenecid MOA ? Common risk factor? - ANSWER -inhibits reabsoprtion of uric acid in PCT - also inhibits secretion of PCN - can cause uric acid calculi 2 causes of SCID include - ANSWER -1.) ADA deficiency (adenosine deaminase required for degradation of adenosim and deoxyadenosine - in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID 2.) (most common) mutations in the gamma chain shared by a number of interleukin receptors (X-SCID) lithiums effects on urination - ANSWER -inhibits vasopression/ADH --> increased urinary frequency —> diabetes insipidus infertility drug that can result in multiple fetuses? MOA? Side effects? - ANSWER -clomiphene (clones- multiple babies) antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback) upregulates LH and FSH release from pituitary --> ovulation 4 | P a g e Created by Grace Amelia © 2025, All Rights Reserved. Used to treat infertility and polycystic ovarian syndrome. may cause hot flashes, ovarian enlargement, multiple simultaneous pregnancies and visual disturbances. AFP levels in down syndrome? - ANSWER -low AFP Which GI malformation is A/W down syndrome - ANSWER -Hirschprungs- congenital aganglionic megacolon defective relaxation and peristalsis of rectum and distal sigmoid colon failure to pass meconium, empty rectal vault, megacolon myasthenia gravis associations - ANSWER -thymoma, thymic hyperplasia ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration tx for tinea? - ANSWER -azoles Can you give beta blockers for asthma? - ANSWER -Nope- even beta 1s can be nonselective at higher doses what kind of teratogenic effects are seen w ACE/ARBs - ANSWER -fetal renal agenesis What does stones bones groans moans psych overtones indicate - ANSWER -high Ca or PTH PTH is made by what cells? - ANSWER -chief cells of parathyroid gland 5 | P a g e Created by Grace Amelia © 2025, All Rights Reserved. PTH inhibits reabsorption of phosphate where? increases calcium resorption where? - ANSWER - PO4- proximal tubule ca- DCT most common cause of cellultis - ANSWER -staph aureus, strep pyogenes FPR- direct or indirect? active or passive? - ANSWER -indirect- place them in position of diagnosis passive cant treat kid w tetracycline so what do you give? - ANSWER -amoxicillin which Heps are there currently vaccines for? - ANSWER -A and B (and so by virtue, also D) why does Hep D need Hep B? - ANSWER -Hep D utilizes the HBV surface antigen as its envelope? most common hepatitis A/W IVDA in the US - ANSWER -hep c Roseola symptoms, population, and cause - ANSWER -4 day high fever then rash on the trunk (spares face) affects babies up to 2 years HHV6- affects CD4 helper cells and kills them off erythema infectiosum is aka? What causes it ? What are the sympto

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COMSAE Cramming Exam Questions and
Answers 100% Pass


drug for UC/Crohns - ANSWER ✔✔-sulfasalazine


pulmonary effects of CF - ANSWER ✔✔-chronic bronchitis and bronchiectasis


osteoporosis affects what parts of bone? - ANSWER ✔✔-(spongy and ) trabecular bone mass loss


Imipramine is what type of drug? - ANSWER ✔✔-TCA




SE: Tri-Cs


convulsions


coma


cardiotox




antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block alpha1)


loratidine vs ranitidine - ANSWER ✔✔-loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less sedating




ranitidine: H2 receptor antagonist (like cimetidine)




H1 think allergies




Created by Grace Amelia © 2025, All Rights Reserved.

,2|Page


H2 think gastric


What organism presents as cells w RBCs inside - ANSWER ✔✔-entaemoba histolytica


which type of pneumothorax causes tracheal deviation to the contra side? - ANSWER ✔✔-tension


intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels -

ANSWER ✔✔-AVM arteriovenous malformation


What is a cavernous hemangioma - ANSWER ✔✔-benign tumor of liver, A/W VHL


anti-HepB surface antibody is only present in what population - ANSWER ✔✔-recovered or immunized




not in chronic or acute


proctalgia fugax is a form of what? - ANSWER ✔✔-levator ani syndrome




Proctalgia fugax is a form of levator syndrome (also called levator ani syndrome). Both include spasms of

muscles in the pelvic area. Proctalgia fugax is temporary, but other types of levator syndrome can last for

several days. Another major difference is the location of the pain.


fasciculus is UMN or LMN lesion? - ANSWER ✔✔-LMN


antibodies in hashimotos attacks - ANSWER ✔✔-thyroid peroxidase or antithyroglobulin




enlarged non tender thyroid


2 factors that influence starling curve - ANSWER ✔✔-x axis- preload (EDV)


y axis- stroke volume or CO




Created by Grace Amelia © 2025, All Rights Reserved.

,3|Page


treatment for fibromyalgia includes - ANSWER ✔✔-TCA, SNRIs anticonvulsants


what drugs block NE reuptake? - ANSWER ✔✔-TCA or SNRIs


possible complication of pagets bone disease - ANSWER ✔✔-osteocarcoma


what does Hct tell you? - ANSWER ✔✔-ratio of volume of RBCs compared to total blood volume


Probenecid MOA ? Common risk factor? - ANSWER ✔✔-inhibits reabsoprtion of uric acid in PCT


- also inhibits secretion of PCN


- can cause uric acid calculi


2 causes of SCID include - ANSWER ✔✔-1.) ADA deficiency


(adenosine deaminase required for degradation of adenosim and deoxyadenosine


- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID




2.) (most common) mutations in the gamma chain shared by a number of interleukin receptors (X-SCID)


lithiums effects on urination - ANSWER ✔✔-inhibits vasopression/ADH --> increased urinary frequency

—> diabetes insipidus


infertility drug that can result in multiple fetuses? MOA? Side effects? - ANSWER ✔✔-clomiphene

(clones- multiple babies)




antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)




upregulates LH and FSH release from pituitary --> ovulation



Created by Grace Amelia © 2025, All Rights Reserved.

, 4|Page




Used to treat infertility and polycystic ovarian syndrome. may cause hot flashes, ovarian enlargement,

multiple simultaneous pregnancies and visual disturbances.


AFP levels in down syndrome? - ANSWER ✔✔-low AFP


Which GI malformation is A/W down syndrome - ANSWER ✔✔-Hirschprungs- congenital aganglionic

megacolon




defective relaxation and peristalsis of rectum and distal sigmoid colon




failure to pass meconium, empty rectal vault, megacolon


myasthenia gravis associations - ANSWER ✔✔-thymoma, thymic hyperplasia




ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration


tx for tinea? - ANSWER ✔✔-azoles


Can you give beta blockers for asthma? - ANSWER ✔✔-Nope- even beta 1s can be nonselective at higher

doses


what kind of teratogenic effects are seen w ACE/ARBs - ANSWER ✔✔-fetal renal agenesis


What does stones bones groans moans psych overtones indicate - ANSWER ✔✔-high Ca or PTH


PTH is made by what cells? - ANSWER ✔✔-chief cells of parathyroid gland




Created by Grace Amelia © 2025, All Rights Reserved.

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