Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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y
Test Bank
y
toyaccompany
Psychopharmacology, Third Edition y y
Meyery•yQuenzer
Chapter 1: Principles of Pharmacology
y y y y
MultipleyChoice
1. y
refer(s)ytoyspecificymolecularychangesythatyoccurywhenyaydrugybindsytoyayparticularytarg
etysiteyoryreceptor,ywhile
areytheyresultingywidespreadyalterationsyinyfunction.
a. Drugyaction;ytherapeuticyeffects
b. Sideyeffects;ydrugyeffects
c. Therapeuticyeffects;ysideyeffects
d. Drugyaction;ydrugyeffects
Answer:yd
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
2. Afterydrugyadministrationyhasyoccurred,ytheyamountyofydrugyinytheybloodythatyisyfreeytoyb
indyatyspecificytargetysitesyisyreferredytoyas
a. theytherapeuticydose.
b. first-passyeffects.
c. bioavailability.
d. ED50.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
3. Theyspecificymolecularychangesythatyoccurywhenyaydrugybindsytoyayparticularytargetysiteyo
ryreceptoryareyreferredytoyas
a. drugyeffects.
b. drugyaction.
c. sideyeffects.
d. placeboyeffects.
Answer:yb
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
4. Whichyofytheyfollowingyisynotyaypossibleyexplanationyforyplaceboyeffects?
a. Pavlovianyconditioning
b. Geneticyvariation
c. Drugycompetition
d. Expectationyofyoutcome
Answer:yc
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
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5. The administrationyofyoxytocinyhasybeenyproposedyasyaytreatmentyforyautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
6. Whichyfactorydoesynotyaffectytheypharmacokineticsyofyaydrug?
a. Routeyofyadministration
b. Lipidysolubility
c. Depotybinding
d. Drugyaction
Answer:yd
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
7. First-passymetabolismyoccursywhenydrugsyareytaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
8. Theyareaypostremayisyoneyareayinytheybrainywhereythe isynotycomplete.
a. cerebrospinalyfluid
b. blood–brainybarrier
c. choroidyplexus
d. phospholipidymembrane
Answer:yb
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
9. First-passymetabolismyoccursywithyorallyyadministeredydrugsybecause
a. theiryabsorptionyisyslowedybyyfood.
b. drugsyabsorbedyintoytheybloodstreamyfromytheystomachygoytoytheyliveryonytheywayytoyg
eneralycirculation.
c. drugsymustyfirstysurviveytheyacidicyenvironmentyofytheystomach.
d. salivaryyenzymesyinytheymouthybeginytheyprocessyofymetabolism.
Answer:yb
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
10. Toxicysubstancesyinytheybloodytriggeryayvomitingyresponseybyyactivatingythe
a. blood–brainybarrier.
b. choroidyplexus.
c. areaypostrema.
d. medianyeminence.
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Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
11. Drugsyadministeredy_ haveytheymostyrapidyonsetyofyaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:yd
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
12. Ionizationyofyaydrugydependsyonythe ofytheysolutionyandythe
ofytheydrug.
a. pH;ypKa
b. pKa;ypH
c. concentration;ylipidysolubility
d. pH;yconcentration
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
13. Theyabsorptionyofyaydrugydependsyonyallyofytheyfollowingyexcept
a. lipidysolubility.
b. ionization.
c. bodyytemperature.
d. theyconcentrationyofytheydrug.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
14. Drugsythatyare shouldybeyavoidedybyywomenyofychildbearingyage.
a. teratogenic
b. ableytoycrossytheyplacentalybarrier
c. psychoactive
d. highlyylipid-soluble
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
15. Agentsythatyinduceydevelopmentalyabnormalitiesyinyayfetusyareyknownyas
a. psychoactiveydrugs.
b. illicitydrugs.
c. teratogens.
d. placentalydrugs.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
16. Depotybindingyisysaidytoyoccurywhenydrugs
a. bindytoytheirytargetysites.
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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
y y y y y y y y y y
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y
Test Bank
y
toyaccompany
Psychopharmacology, Third Edition y y
Meyery•yQuenzer
Chapter 1: Principles of Pharmacology
y y y y
MultipleyChoice
1. y
refer(s)ytoyspecificymolecularychangesythatyoccurywhenyaydrugybindsytoyayparticularytarg
etysiteyoryreceptor,ywhile
areytheyresultingywidespreadyalterationsyinyfunction.
a. Drugyaction;ytherapeuticyeffects
b. Sideyeffects;ydrugyeffects
c. Therapeuticyeffects;ysideyeffects
d. Drugyaction;ydrugyeffects
Answer:yd
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
2. Afterydrugyadministrationyhasyoccurred,ytheyamountyofydrugyinytheybloodythatyisyfreeytoyb
indyatyspecificytargetysitesyisyreferredytoyas
a. theytherapeuticydose.
b. first-passyeffects.
c. bioavailability.
d. ED50.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
3. Theyspecificymolecularychangesythatyoccurywhenyaydrugybindsytoyayparticularytargetysiteyo
ryreceptoryareyreferredytoyas
a. drugyeffects.
b. drugyaction.
c. sideyeffects.
d. placeboyeffects.
Answer:yb
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
4. Whichyofytheyfollowingyisynotyaypossibleyexplanationyforyplaceboyeffects?
a. Pavlovianyconditioning
b. Geneticyvariation
c. Drugycompetition
d. Expectationyofyoutcome
Answer:yc
TextbookyReference:yPharmacology:yTheyScienceyofyDrugyAction
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5. The administrationyofyoxytocinyhasybeenyproposedyasyaytreatmentyforyautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
6. Whichyfactorydoesynotyaffectytheypharmacokineticsyofyaydrug?
a. Routeyofyadministration
b. Lipidysolubility
c. Depotybinding
d. Drugyaction
Answer:yd
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
7. First-passymetabolismyoccursywhenydrugsyareytaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
8. Theyareaypostremayisyoneyareayinytheybrainywhereythe isynotycomplete.
a. cerebrospinalyfluid
b. blood–brainybarrier
c. choroidyplexus
d. phospholipidymembrane
Answer:yb
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
9. First-passymetabolismyoccursywithyorallyyadministeredydrugsybecause
a. theiryabsorptionyisyslowedybyyfood.
b. drugsyabsorbedyintoytheybloodstreamyfromytheystomachygoytoytheyliveryonytheywayytoyg
eneralycirculation.
c. drugsymustyfirstysurviveytheyacidicyenvironmentyofytheystomach.
d. salivaryyenzymesyinytheymouthybeginytheyprocessyofymetabolism.
Answer:yb
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
10. Toxicysubstancesyinytheybloodytriggeryayvomitingyresponseybyyactivatingythe
a. blood–brainybarrier.
b. choroidyplexus.
c. areaypostrema.
d. medianyeminence.
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Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
11. Drugsyadministeredy_ haveytheymostyrapidyonsetyofyaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:yd
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
12. Ionizationyofyaydrugydependsyonythe ofytheysolutionyandythe
ofytheydrug.
a. pH;ypKa
b. pKa;ypH
c. concentration;ylipidysolubility
d. pH;yconcentration
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
13. Theyabsorptionyofyaydrugydependsyonyallyofytheyfollowingyexcept
a. lipidysolubility.
b. ionization.
c. bodyytemperature.
d. theyconcentrationyofytheydrug.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
14. Drugsythatyare shouldybeyavoidedybyywomenyofychildbearingyage.
a. teratogenic
b. ableytoycrossytheyplacentalybarrier
c. psychoactive
d. highlyylipid-soluble
Answer:ya
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
15. Agentsythatyinduceydevelopmentalyabnormalitiesyinyayfetusyareyknownyas
a. psychoactiveydrugs.
b. illicitydrugs.
c. teratogens.
d. placentalydrugs.
Answer:yc
TextbookyReference:yPharmacokineticyFactorsyDeterminingyDrugyAction
16. Depotybindingyisysaidytoyoccurywhenydrugs
a. bindytoytheirytargetysites.
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