BIO 351 MODULE 5 TEST QUESTIONS AND
ANSWERS
The craniofacial skeletal tissues are primarily derived from a
combination of ___________ and _________? - ANSWER Cranial
neural crest, mesoderm
Which of the following embryonic structures gives rise to Meckel's
cartilage, the precursor of the mandible? - ANSWER Pharyngeal Arch
1
Which of the following are necessary for cranial neural crest cell
multipotency and survival? - ANSWER FGF8
A farmer has several ewes that give birth to lambs with cyclopia and
midline craniofacial defects. This is most likely due to which of the
following? - ANSWER Exposure to agents that antagonize Shh
signalling
In the early embryo what signals must occur together in the splanchnic
mesoderm for cardiogenic mesoderm to be specified? - ANSWER
DKK, Crescent, Cereberus, FGF8, and BMP
Which of the following represents an important outcome of looping? -
ANSWER Establishment of left-right asymmetry
During heart development which of the following represent the correct
temporal events in morphogenesis? - ANSWER A. Formation of heart
primordia, formation of the linear heart tube, looping, and septation
Defects in endocardial cushions are often associated with craniofacial
defects suggesting a common link to neural crest cells. - ANSWER
True
The neural crest is derived from _______. An important step in neural
crest induction is activation of the __________ promoter. Fill in the
blanks with best answer. - ANSWER ectoderm, β-catenin
ANSWERS
The craniofacial skeletal tissues are primarily derived from a
combination of ___________ and _________? - ANSWER Cranial
neural crest, mesoderm
Which of the following embryonic structures gives rise to Meckel's
cartilage, the precursor of the mandible? - ANSWER Pharyngeal Arch
1
Which of the following are necessary for cranial neural crest cell
multipotency and survival? - ANSWER FGF8
A farmer has several ewes that give birth to lambs with cyclopia and
midline craniofacial defects. This is most likely due to which of the
following? - ANSWER Exposure to agents that antagonize Shh
signalling
In the early embryo what signals must occur together in the splanchnic
mesoderm for cardiogenic mesoderm to be specified? - ANSWER
DKK, Crescent, Cereberus, FGF8, and BMP
Which of the following represents an important outcome of looping? -
ANSWER Establishment of left-right asymmetry
During heart development which of the following represent the correct
temporal events in morphogenesis? - ANSWER A. Formation of heart
primordia, formation of the linear heart tube, looping, and septation
Defects in endocardial cushions are often associated with craniofacial
defects suggesting a common link to neural crest cells. - ANSWER
True
The neural crest is derived from _______. An important step in neural
crest induction is activation of the __________ promoter. Fill in the
blanks with best answer. - ANSWER ectoderm, β-catenin
