MCB 3020 Final Exam UPDATED
Questions and CORRECT Answers
To establish infection what must a microorganism do? - CORRECT ANSWER -
Overcome surface barriers such as the skin, degradative enzymes, and mucus
Skin, degradative enzymes and mucus - CORRECT ANSWER - Direct antimicrobial
activity or inhibit attachment of the microorganisms to the host
Are skin and mucous-lined body cavities ideal environments for the vast majority of
microrganisms? - CORRECT ANSWER - No
Most pathogens (Disease causing organisms must breach these barriers, and reach the underlying
tissues to cause disease
Any microorganism that penetrates the barriers of the human body encounters? - CORRECT
ANSWER - Two levels of host defenses
Innate resistance mechanisms
An adaptive immune response
Immune system is composed of ? - CORRECT ANSWER - Widely distributed proteins,
cells, tissues, and organs that recognize foreign substances, including microorganism
Together they act to neutralize or destroy them, maintaining host integrity
Immunity - CORRECT ANSWER - Ability of a host to resist infection or disease
, Immunology - CORRECT ANSWER - Science of immune responses and how these
responses are used to resist infection
Includes the distinction between "sef" and "nonself" and all the biological, chemical,
physiological, metabolic, and physical aspects of the immune response
Innate resistance mechanisms - CORRECT ANSWER - Common to all vertebrate animals,
which gave evolved unique features that inherently protect against invasion by foreign
substances.
Some are physical and act as barriers
Others are chemical in nature and directly kill or inhibit invaders
Major Histocompatibility Complex (MHC) - CORRECT ANSWER - collection of genes
and encoding proteins that enable the host to distinguish between self and nonself.
Human MHC is located in which chromosome? - CORRECT ANSWER - Chromosome 6,
termed the human leukocyte antigen
What are the three classes of of HLA proteins? - CORRECT ANSWER - Class I, class II,
class III
Class I MHC molecules - CORRECT ANSWER - include HLA types A, B,C and serve to
identify almost all cells of the body as self
-found on all nucleated body cells
Describe the protein chains making up the class I MHC molecules - CORRECT
ANSWER - -heterodimer consisting of the alpha chain (a1,a2,a3, and the B2m)
Questions and CORRECT Answers
To establish infection what must a microorganism do? - CORRECT ANSWER -
Overcome surface barriers such as the skin, degradative enzymes, and mucus
Skin, degradative enzymes and mucus - CORRECT ANSWER - Direct antimicrobial
activity or inhibit attachment of the microorganisms to the host
Are skin and mucous-lined body cavities ideal environments for the vast majority of
microrganisms? - CORRECT ANSWER - No
Most pathogens (Disease causing organisms must breach these barriers, and reach the underlying
tissues to cause disease
Any microorganism that penetrates the barriers of the human body encounters? - CORRECT
ANSWER - Two levels of host defenses
Innate resistance mechanisms
An adaptive immune response
Immune system is composed of ? - CORRECT ANSWER - Widely distributed proteins,
cells, tissues, and organs that recognize foreign substances, including microorganism
Together they act to neutralize or destroy them, maintaining host integrity
Immunity - CORRECT ANSWER - Ability of a host to resist infection or disease
, Immunology - CORRECT ANSWER - Science of immune responses and how these
responses are used to resist infection
Includes the distinction between "sef" and "nonself" and all the biological, chemical,
physiological, metabolic, and physical aspects of the immune response
Innate resistance mechanisms - CORRECT ANSWER - Common to all vertebrate animals,
which gave evolved unique features that inherently protect against invasion by foreign
substances.
Some are physical and act as barriers
Others are chemical in nature and directly kill or inhibit invaders
Major Histocompatibility Complex (MHC) - CORRECT ANSWER - collection of genes
and encoding proteins that enable the host to distinguish between self and nonself.
Human MHC is located in which chromosome? - CORRECT ANSWER - Chromosome 6,
termed the human leukocyte antigen
What are the three classes of of HLA proteins? - CORRECT ANSWER - Class I, class II,
class III
Class I MHC molecules - CORRECT ANSWER - include HLA types A, B,C and serve to
identify almost all cells of the body as self
-found on all nucleated body cells
Describe the protein chains making up the class I MHC molecules - CORRECT
ANSWER - -heterodimer consisting of the alpha chain (a1,a2,a3, and the B2m)
