PCOL-INTRO EXAM QUESTIONS AND
ANSWERS
pharmacy - correct answer-Science of:
- Identification
- Selection
- Preservation
- Standardization
- Compounding
- Dispensing OF MEDICINAL SUBSTANCES
pharmacology - correct answer-Science about effects of drugs on the body
drug - correct answer-any substance or product that is used or intended to be used to
modify, explore physiological system or cure pathological states for the benefit of the
recipient
materia medica - correct answer-the precursor to pharmacology; developed from the
ancient practice of shamans and spirits in attending to sick
pharmacognosy - correct answer-the science of identification of drugs; most used drug
source are plants
clinical pharmacy - correct answer-Involves the cooperation of PHARMACIST with
PHYSICIANS In educating patients about compliance, and counseling him on how to
take the medicines and monitor errors in drug therapy
Pharmacokinetics - correct answer-the movement of drugs in the body; study of the
"ADME" system
pharmacodynamics - correct answer-Study of the action, biologic & therapeutic
effects of drugs; "what the drug does to the body'
therapeutics - correct answer-deals with the CURE of the disease and RELIEF of the
symptoms; it involves both pharmacologic and nonpharmacologic
toxicology - correct answer-the study of poisons
pharmacoepidemiology - correct answer-It is the study of effects and uses of drugs in
large number of people
, Pharmacoeconimics - correct answer-It is the analysis of the cost of drug therapy to the
healthcare system and the society.
pharmacogenomics - correct answer-science that examines the variation in genes that
dictates the drug response; Explores the ways these variations can be used to predict
whether a response
agonist - correct answer-activator of a specific molecule
antagonist - correct answer-inhibitor of specific molecule
receptor - correct answer-target molecule for the drug
xenobiotics - correct answer-chemicals not synthesized in the body
poison - correct answer-drugs that have almost exclusively harmful effects
toxin - correct answer-which refers to poison of biologic origin and usually synthesized
by plants or animals
posology - correct answer-study of doses
channel-linked - correct answer-ionotropic; a receptor -effector linkage which happens
in milliseconds; nicotinic ACh receptor
g-protein coupled receptors - correct answer-metabotropic; a receptor -effector linkage
which happens in seconds; muscarinic ACh receptor
kinase-linked - correct answer-a receptor -effector linkage which happens in minutes;
insulin receptor
nuclear receptor - correct answer-a receptor -effector linkage which happens in hours;
estrogen receptor
excitatory post synaptic potentials [EPSP] - correct answer-These are ion channels
which are initiated when excitatory neurotransmitter activates Na+ or Ca+2 channels
IPSP (inhibitory post synaptic potentials) - correct answer-ion channels which are
initiated when an inhibitory neurotransmitter open Cl- and K+ channels and membrane
becomes hyperpolarized
Ligand gated or receptor operated ion channel (ROC) - correct answer-ion channels
which are activated when a drug or an endogenous substance (neurotransmitter) binds
with a specific receptor thus increasing transmembrane conductance of the relevant ion
and thereby altering the electrical potential across the membrane
ANSWERS
pharmacy - correct answer-Science of:
- Identification
- Selection
- Preservation
- Standardization
- Compounding
- Dispensing OF MEDICINAL SUBSTANCES
pharmacology - correct answer-Science about effects of drugs on the body
drug - correct answer-any substance or product that is used or intended to be used to
modify, explore physiological system or cure pathological states for the benefit of the
recipient
materia medica - correct answer-the precursor to pharmacology; developed from the
ancient practice of shamans and spirits in attending to sick
pharmacognosy - correct answer-the science of identification of drugs; most used drug
source are plants
clinical pharmacy - correct answer-Involves the cooperation of PHARMACIST with
PHYSICIANS In educating patients about compliance, and counseling him on how to
take the medicines and monitor errors in drug therapy
Pharmacokinetics - correct answer-the movement of drugs in the body; study of the
"ADME" system
pharmacodynamics - correct answer-Study of the action, biologic & therapeutic
effects of drugs; "what the drug does to the body'
therapeutics - correct answer-deals with the CURE of the disease and RELIEF of the
symptoms; it involves both pharmacologic and nonpharmacologic
toxicology - correct answer-the study of poisons
pharmacoepidemiology - correct answer-It is the study of effects and uses of drugs in
large number of people
, Pharmacoeconimics - correct answer-It is the analysis of the cost of drug therapy to the
healthcare system and the society.
pharmacogenomics - correct answer-science that examines the variation in genes that
dictates the drug response; Explores the ways these variations can be used to predict
whether a response
agonist - correct answer-activator of a specific molecule
antagonist - correct answer-inhibitor of specific molecule
receptor - correct answer-target molecule for the drug
xenobiotics - correct answer-chemicals not synthesized in the body
poison - correct answer-drugs that have almost exclusively harmful effects
toxin - correct answer-which refers to poison of biologic origin and usually synthesized
by plants or animals
posology - correct answer-study of doses
channel-linked - correct answer-ionotropic; a receptor -effector linkage which happens
in milliseconds; nicotinic ACh receptor
g-protein coupled receptors - correct answer-metabotropic; a receptor -effector linkage
which happens in seconds; muscarinic ACh receptor
kinase-linked - correct answer-a receptor -effector linkage which happens in minutes;
insulin receptor
nuclear receptor - correct answer-a receptor -effector linkage which happens in hours;
estrogen receptor
excitatory post synaptic potentials [EPSP] - correct answer-These are ion channels
which are initiated when excitatory neurotransmitter activates Na+ or Ca+2 channels
IPSP (inhibitory post synaptic potentials) - correct answer-ion channels which are
initiated when an inhibitory neurotransmitter open Cl- and K+ channels and membrane
becomes hyperpolarized
Ligand gated or receptor operated ion channel (ROC) - correct answer-ion channels
which are activated when a drug or an endogenous substance (neurotransmitter) binds
with a specific receptor thus increasing transmembrane conductance of the relevant ion
and thereby altering the electrical potential across the membrane
