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Exam 3: NURS617/ NURS 617 (Latest 2024/ 2025 Update) Pharmacotherapeutics Review| Qs & As| Grade A| 100% Correct (Verified Answers)- Southeastern Louisiana

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Exam 3: NURS617/ NURS 617 (Latest 2024/ 2025 Update) Pharmacotherapeutics Review| Qs & As| Grade A| 100% Correct (Verified Answers)- Southeastern Louisiana Q: Which thyroid medication is most cardiotoxic Answer: Liothyronine Q: Which thyroid medication has the disadvantage of not having content stability Answer: Liotrix Q: What are some advantages of Liothyronine over Levothyroxine Answer: Liothyronine has a faster onset of action and is more potent. Q: Advantage of using Levothyroxine over Liothyronine Answer: Less cardiotoxic and has a longer duration of action meaning that even if some doses are missed thyroid levels can remain therapeutic. Q: What are some signs of Thyroid medication toxicity? Answer: irritability, insomnia, tachycardia, arrhythmias, elevated blood pressure, anxiety, weight loss, all similar signs of hyperthyroidism. Q: Which antithyroid drug is used in pregnancy Answer: Propylthiouracil Q: Which antithyroid drug has a black box warning for liver injury Answer: Propylthiouracil Q: Advantages of Methimazole over Propylthiouracil Answer: Methimazole is more potent, less toxic, not protein bound, and does not carry black box warning about liver damage Q: What adverse reactions can antithyroid medications cause Answer: Allergic reactions such as rash, and urticaria; Nausea and vomiting during initiation of therapy; agranulocytosis and thrombocytopenia; Hypothyroidism (with long term therapy); reoccurrence of hyperthyroidism after stopping treatment. Q: Which antidiabetics cause hypoglycemia Answer: Sulfonylureas, meglitinides, amylin agonists can all cause hypoglycemia. Thiazolidinediones, Alpha Glucose inhibitors, and GLP-1 analogs can potentiate hypoglycemia when given with other antidiabetics. Q: Which anti-diabetics are nephroprotective Answer: DPP-4 (-gliptins) because in patients without severe renal impairment, the typical progression of microalbuminuria to proteinuria in DM appears to be reversed after 2 years on saxagliptin use Q: Which anti-diabetics require dosage adjustments for renal impairment. Answer: DPP-4 (gliptins) and SGLT-2 inhibitors require dosage adjustments while Metformin and Sulfonylureas are contraindicated in patients with renal failure. Q: Which anti-diabetic medications are contraindicated in Liver disease Answer: Metformin, Sulfonylureas, and Thiazolidinediones

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Institution
Southeastern Louisiana University
Course
NURS617/ NURS 617 (NURS617)

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Examl3:lNURS617/lNURSl617l(Latestl
Update)lPharmacotherapeuticslReview|lQsl
&lAs|lGradelA|l100%lCorrectl(Verifiedl
Answers)-lSoutheasternlLouisiana

Q:lWhichlthyroidlmedicationlislmostlcardiotoxic

Answer:
Liothyronine




Q:lWhichlthyroidlmedicationlhasltheldisadvantageloflnotlhavinglcontentlstability

Answer:
Liotrix




Q:lWhatlarelsomeladvantagesloflLiothyronineloverlLevothyroxine

Answer:
Liothyroninelhaslalfasterlonsetloflactionlandlislmorelpotent.




Q:lAdvantageloflusinglLevothyroxineloverlLiothyronine

Answer:
Lesslcardiotoxiclandlhaslallongerldurationloflactionlmeaninglthatlevenliflsomeldoseslarelmissed
lthyroidllevelslcanlremainltherapeutic.

,Q:lWhatlarelsomelsignsloflThyroidlmedicationltoxicity?

Answer:
irritability,linsomnia,ltachycardia,larrhythmias,lelevatedlbloodlpressure,lanxiety,lweightlloss,lalll
similarlsignsloflhyperthyroidism.




Q:lWhichlantithyroidldruglislusedlinlpregnancy

Answer:
Propylthiouracil




Q:lWhichlantithyroidldruglhaslalblacklboxlwarninglforlliverlinjury

Answer:
Propylthiouracil




Q:lAdvantagesloflMethimazoleloverlPropylthiouracil

Answer:
Methimazolelislmorelpotent,llessltoxic,lnotlproteinlbound,landldoeslnotlcarrylblacklboxlwarnin
glaboutlliverldamage




Q:lWhatladverselreactionslcanlantithyroidlmedicationslcause

Answer:

, Allergiclreactionslsuchlaslrash,landlurticaria;lNausealandlvomitinglduringlinitiationlofltherapy;l
agranulocytosislandlthrombocytopenia;lHypothyroidisml(withllongltermltherapy);lreoccurrencel
oflhyperthyroidismlafterlstoppingltreatment.




Q:lWhichlantidiabeticslcauselhypoglycemia

Answer:
Sulfonylureas,lmeglitinides,lamylinlagonistslcanlalllcauselhypoglycemia.l
Thiazolidinediones,lAlphalGlucoselinhibitors,landlGLP-
1lanalogslcanlpotentiatelhypoglycemialwhenlgivenlwithlotherlantidiabetics.




Q:lWhichlanti-diabeticslarelnephroprotective

Answer:
DPP-4l(-
gliptins)lbecauselinlpatientslwithoutlseverelrenallimpairment,ltheltypicallprogressionloflmicroal
buminurialtolproteinurialinlDMlappearsltolbelreversedlafterl2lyearslonlsaxagliptinluse




Q:lWhichlanti-diabeticslrequireldosageladjustmentslforlrenallimpairment.

Answer:
DPP-4l(gliptins)landlSGLT-2linhibitorslrequireldosageladjustmentslwhilel
MetforminlandlSulfonylureaslarelcontraindicatedlinlpatientslwithlrenallfailure.




Q:lWhichlanti-diabeticlmedicationslarelcontraindicatedlinlLiverldisease

Answer:
Metformin,lSulfonylureas,landlThiazolidinediones
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Course
NURS617/ NURS 617 (NURS617)
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