PHRM30002 – Glia Exam Questions With Correct Answers

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PHRM30002 – Glia Exam Questions With
Correct Answers


Microglia are immune cells, Astrocytes affect synapses and cover endothelium,

Oligodendrocytes wrap neurons to form myelin sheath - answer✔What are three major types

of glia and what do they do?


Directly modulate neuronal function - answer✔Not only can the glia support neurons, what else

do they do?


Damage may lead to demyelination, affecting ap propogation and thus CNS function -

answer✔How can oligodendrocytes be so core to CNS function?


Can alter phenotype to change release of chemo/cytokines, there are multitude of pro and anti

inflammatory phentypes - answer✔What do microglia often do in response to stimuli? What

complicates the targetting of this?


Synaptic pruning by phagocytosis of neurons, can be excessively done in disease -

answer✔What is the main process of microglia? What often goes wrong with this in disease?


Can release pro-inflammatory cytokines - answer✔Like microglia, how can astrocytes promote

inflammation?

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