RBC Morphology Exam 3 100% Verified
discocyte
biconcanve, central pallor
normal RBC shape
poikilocytosis
variation in cell shapes
when >10% of total RBCs are variable shaped
newborns (especially ruminants)
what is poikilocytosis more common in?
physiologic response, cell damage, infectious organism, artifact
what are some of the causes of poikilocytosis?
goats
what species can poikilocytosis be normal in?
anisocytosis
varying cell sizes present
macrocytes
larger than normal
see with immature RBCs (regenerative response), cell maturation disorders
, microcytes
smaller than normal
see with RBC nutrient deficiencies (iron), conditions that remove bits of RBCs like
immune mediated hemolytic anemia (IMHA)
macrocytes, microcytes, normocytes
types of anisocytosis
polychromatic
an RBC with a basophilia (blue coloration)
polychromasia
several polychromatic RBCs
horses
what is polychromasia not seen in?
regeneration
what does polychromasia indicate?
polychromasia
immature RBCs that have been released early are frequently macrocytic too
with new methylene blue stain, many will be reticulocytes
rouleaux
RBCs stack in a linear arrangement
discocyte
biconcanve, central pallor
normal RBC shape
poikilocytosis
variation in cell shapes
when >10% of total RBCs are variable shaped
newborns (especially ruminants)
what is poikilocytosis more common in?
physiologic response, cell damage, infectious organism, artifact
what are some of the causes of poikilocytosis?
goats
what species can poikilocytosis be normal in?
anisocytosis
varying cell sizes present
macrocytes
larger than normal
see with immature RBCs (regenerative response), cell maturation disorders
, microcytes
smaller than normal
see with RBC nutrient deficiencies (iron), conditions that remove bits of RBCs like
immune mediated hemolytic anemia (IMHA)
macrocytes, microcytes, normocytes
types of anisocytosis
polychromatic
an RBC with a basophilia (blue coloration)
polychromasia
several polychromatic RBCs
horses
what is polychromasia not seen in?
regeneration
what does polychromasia indicate?
polychromasia
immature RBCs that have been released early are frequently macrocytic too
with new methylene blue stain, many will be reticulocytes
rouleaux
RBCs stack in a linear arrangement
