Basic and Clinical Pharmacology, 15th Edition TEST BANK by Bertram G. Katzung, Verified Chapters 1 - 66

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BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION
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KATZUNG TREVOR TEST BANK
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INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS
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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a patient who is
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having a computed tomography (CT) scan. The nurse working on the
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oncology unit administers chemotherapy to patients who have cancer.
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At the Public Health Department, a nurse administers a measles-
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mumps-rubella (MMR) vaccine to a 14-month-old child as a routine
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immunization. Which branch of pharmacology best describes the
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actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacology is the study of the biologic effects of chemicals.
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Nurses are involved with clinical pharmacology or
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pharmacotherapeutics, which is a branch of pharmacology that deals
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with the uses of drugs to treat, prevent, and diagnose disease. The
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radiology nurse is administering a drug to help diagnose a disease.
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The oncology nurse is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and nm nm nm nm nm nm nm nm


pharmacokinetics is how the body acts on the body.
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2. When involved in phase III drug evaluation studies,
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what responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:

Phase III studies involve use of a drug in a vast clinical population in
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which patients are asked to record any symptoms they experience
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while taking the drugs. Nurses may be responsible for helping
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collect and analyze the information to be shared with the Food and
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Drug Administration (FDA) but would not conduct research
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independently because nurses do not prescribe medications. Use of
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animals in drug testing is done in the preclinical trials. Select
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patients who are involved in phase II studies to participate in studies
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where the participants have the disease the drug is intended to treat.
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These patients are monitored closely for drug action and adverse
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effects. Phase I studies involve healthy human volunteers who are
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usually paid for their participation. Nurses may observe for adverse
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effects and toxicity.
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3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle
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accident victim. The nurse is aware this drug has a high abuse
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potential. Under what category would morphine be classified?
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A) Schedule I nm




B) Schedule II nm




C) Schedule III nm




D) Schedule IV nm




Ans: B
Feedback:

Narcotics with a high abuse potential are classified as Schedule II
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drugs because of severe dependence liability. Schedule I drugs have
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high abuse potential and no accepted medical use. Schedule III
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drugs have a lesser abuse potential than II and an accepted medical
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use. Schedule IV drugs have low abuse potential and limited
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dependence liability.
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4. What concept is considered when generic drugs are substituted for
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brand name drugs?
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A) Bioavailability

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