, 18th Edition
HARRISON’S
g
®g
g
INTERNAL
Principles of
g
g
MEDICINE
SELF-
ASSESSMENT AND BOA
g g
RD REVIEW
g
, Editorial Board g
DANg L.g LONGO,g MD
Professorg ofg Medicine,g Harvardg Medicalg SchoolgS
eniorg Physician,g Brighamg andg Women’sg Hospitalg
Deputyg Editor,g Newg Englandg Journalg ofg Medicin
egBoston,gMassachusetts
ANTHONYg S.g FAUCI,g MD
Chief,g Laboratoryg ofg Immunoregulation
Director,gNationalg Instituteg ofg Allergyg andg Infectiousg Disease
sgNationalgInstitutesgofgHealth
Bethesda,gMaryland
DENNISg L.g KASPER,g MD
Williamg Elleryg Channingg Professorg ofg MedicinegP
rofessorg ofg Microbiologyg andg Molecularg Geneticsg
HarvardgMedicalgSchool
Director,g Channingg Laboratory
Departmentg ofg Medicine,g Brighamg andg Women’sg HospitalgBo
ston,gMassachusetts
STEPHENg L.g HAUSER,g MD
Robertg A.g Fishmang Distinguishedg Professorg andg ChairmangD
epartmentgofgNeurology,gUniversitygofgCalifornia
Sang Francisco,g California
J.g LARRYg JAMESON,g MD,g PHD
RobertgG.gDunlopgProfessorgofgMedicinegDe
an,g UniversitygofgPennsylvaniag Schoolg ofg Medicine
Executiveg Vice-
Presidentg ofgthegUniversitygofg Pennsylvaniag forg theg HealthgSyste
mgPhiladelphia,gPennsylvania
JOSEPHg LOSCALZO,g MD,g PHD
Herseyg Professorg ofg theg Theoryg andg Practiceg ofg MedicinegHarva
rdgMedicalgSchool
Chairman,gDepartmentgofgMedicinegPhysi
cian-in-Chief,g Brighamg andg Women’sg Hospital
Boston,g Massachusetts
, 18th Edition
HARRISON’S
g
®g
g
INTERNAL
Principles of
g
g
MEDICINE
SELF-
ASSESSMENT AND B g g
OARD REVIEW g
Forgusegwithgtheg18thgeditiongofgHARRISON’SgPRINCIPLESgOFgINTERNALgMEDICINE
EDITED BY g
CHARLES M. WIENER, MD g g g
Dean/CEO
Perdanag Universityg Graduateg Schoolg ofg MedicinegSelangor
,gMalaysia
Professorg ofg Medicineg andg Physiology
Johnsg Hopkinsg Universityg Schoolg ofg MedicinegBaltimor
e,gMaryland
CYNTHIA D. BROWN, MDg g g
Assistantg Professorg ofg Medicine
Divisiong ofg Pulmonaryg andg Criticalg Careg MedicinegUniversit
yg ofgVirginia
Charlottesville,gVirginia
ANNA R. HEMNES, MD
g g g
Assistantg Professor,gDivisiongofgAllergy,gPulmonary,gan
dgCriticalg CaregMedicine
Vanderbiltg Universityg Medicalg CentergNashville
,gTennessee
NewgYorkg Chicagog SangFranciscog Lisbong London
Madridg MexicogCityg
Milang NewgDelhig SangJuang Seoulg Singaporeg Sydneyg Toronto
HARRISON’S
g
®g
g
INTERNAL
Principles of
g
g
MEDICINE
SELF-
ASSESSMENT AND BOA
g g
RD REVIEW
g
, Editorial Board g
DANg L.g LONGO,g MD
Professorg ofg Medicine,g Harvardg Medicalg SchoolgS
eniorg Physician,g Brighamg andg Women’sg Hospitalg
Deputyg Editor,g Newg Englandg Journalg ofg Medicin
egBoston,gMassachusetts
ANTHONYg S.g FAUCI,g MD
Chief,g Laboratoryg ofg Immunoregulation
Director,gNationalg Instituteg ofg Allergyg andg Infectiousg Disease
sgNationalgInstitutesgofgHealth
Bethesda,gMaryland
DENNISg L.g KASPER,g MD
Williamg Elleryg Channingg Professorg ofg MedicinegP
rofessorg ofg Microbiologyg andg Molecularg Geneticsg
HarvardgMedicalgSchool
Director,g Channingg Laboratory
Departmentg ofg Medicine,g Brighamg andg Women’sg HospitalgBo
ston,gMassachusetts
STEPHENg L.g HAUSER,g MD
Robertg A.g Fishmang Distinguishedg Professorg andg ChairmangD
epartmentgofgNeurology,gUniversitygofgCalifornia
Sang Francisco,g California
J.g LARRYg JAMESON,g MD,g PHD
RobertgG.gDunlopgProfessorgofgMedicinegDe
an,g UniversitygofgPennsylvaniag Schoolg ofg Medicine
Executiveg Vice-
Presidentg ofgthegUniversitygofg Pennsylvaniag forg theg HealthgSyste
mgPhiladelphia,gPennsylvania
JOSEPHg LOSCALZO,g MD,g PHD
Herseyg Professorg ofg theg Theoryg andg Practiceg ofg MedicinegHarva
rdgMedicalgSchool
Chairman,gDepartmentgofgMedicinegPhysi
cian-in-Chief,g Brighamg andg Women’sg Hospital
Boston,g Massachusetts
, 18th Edition
HARRISON’S
g
®g
g
INTERNAL
Principles of
g
g
MEDICINE
SELF-
ASSESSMENT AND B g g
OARD REVIEW g
Forgusegwithgtheg18thgeditiongofgHARRISON’SgPRINCIPLESgOFgINTERNALgMEDICINE
EDITED BY g
CHARLES M. WIENER, MD g g g
Dean/CEO
Perdanag Universityg Graduateg Schoolg ofg MedicinegSelangor
,gMalaysia
Professorg ofg Medicineg andg Physiology
Johnsg Hopkinsg Universityg Schoolg ofg MedicinegBaltimor
e,gMaryland
CYNTHIA D. BROWN, MDg g g
Assistantg Professorg ofg Medicine
Divisiong ofg Pulmonaryg andg Criticalg Careg MedicinegUniversit
yg ofgVirginia
Charlottesville,gVirginia
ANNA R. HEMNES, MD
g g g
Assistantg Professor,gDivisiongofgAllergy,gPulmonary,gan
dgCriticalg CaregMedicine
Vanderbiltg Universityg Medicalg CentergNashville
,gTennessee
NewgYorkg Chicagog SangFranciscog Lisbong London
Madridg MexicogCityg
Milang NewgDelhig SangJuang Seoulg Singaporeg Sydneyg Toronto
