PNN Day 4 - HIV/Calculations (Questions + Answers) Verified 100% Correct!!.

PNN Day 4 - HIV/Calculations
Nucleoside reverse transcriptase inhibitors: drugs - ✔️✔️ZALES DT

- zidovudine
- abacavir
- lamivudine
- emtricitabine
- stavudine
- didanosine
- tenofovir (nucleoTide-RTI)

Abacavir: genetic testing - ✔️✔️HLA-B 5701

Zidovudine: AE - ✔️✔️**MYELOSUPPRESSION (BBW)
Lactic acidosis (BBW)
Hepatic steatosis (BBW)
Myopathy (BBW)
Lipoatrophy
Headache
N/V
Purple discoloration
Molecular weight of phosphorus - ✔️✔️31

Molecular weight of sulfur - ✔️✔️32

HIV: diagnosis - ✔️✔️1. ELISA
2. if ELISA +, then Western blot test

Tests for initial HIV visit - ✔️✔️1. CD4 count
2. viral load
3. drug resistance

Home HIV test systems - ✔️✔️1. Home access HIV-1
2. OraQuick

Selzentry: dose - ✔️✔️300 mg BID

Selzentry: dose adjustments with other drugs - ✔️✔️CYP3A inhibitors: 150 mg BID
CYP3A inducers: 600 mg BID

Ibalizumab: role in therapy - ✔️✔️mult-drug-resistant HIV failing current regimen

Ibalizumab-uiyk: AE - ✔️✔️- increase uric acid

, - dizziness
- rash
- diarrhea

Ibalizumab-uiyk: formulation - ✔️✔️IV

Selzentry: test - ✔️✔️Tropism test to decide whether CCR5 blocker will be useful in
patient

Binding inhibitors: drugs - ✔️✔️- ibalizumab-uiyk (blocks CD4)
- selzentry (blocks CCR5)

Molecular weight of sodium - ✔️✔️23

Molecular weight of chlorine - ✔️✔️35.5

Molecular weight of potassium - ✔️✔️39

Molecular weight of calcium - ✔️✔️40

Molecular weight of oxygen - ✔️✔️16

Molecular weight of hydrogen - ✔️✔️1

Molecular weight of nitrogen - ✔️✔️14

Fusion inhibitor: drug - ✔️✔️enfuvirtide (targets gp41)



Drugs that may cause myopathy - ✔️✔️Zidovudine
Statins
Daptomycin
Lyrica

Zidovudine: brand - ✔️✔️Retrovir

Lamivudine: brand - ✔️✔️Epivir
Epivir-HBV

Abacavir: brand - ✔️✔️Ziagen

Enfuvirtide: brand - ✔️✔️Fuzeon