TEST BANK FOR Understanding Pharmacology, Essentials for Medication Safety, 2nd Edition, Workman & La Charity

TEST BANK FOR Understanding Pharmacology, Essentials for
m m m m m m m



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m m m m m m m m



GRADED( ALL CHAPTERS COVERED)
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Chapterm01:mDrugmRegulation,mActions,mandmResponses
Workmanm&mLaCharity:mUnderstandingmPharmacology:mEssentialsmformMedicationmSafety,m2
ndmEdition

MULTIPLEmCHOICEm

BASICmCONCEPT

S

1. Whichmhealthmcaremprofessionalmhasmthemmajormresponsibilitymformdispensingmprescrib
edmdrugsmundermthemdirectionmofmampharmacist?
a. Physician
b Nursempractitioner
.
c. Licensedmnurse
d Pharmacymtechnician
.


ANS:m D
Themphysicianmandmnursempractitionermhavemthemmajormresponsibilitymformprescribingmdrugs,mnot
mdispensingmthem.mThemlicensedmnursemhasmthemprimarymresponsibilitymformadministeringmdrugs,

malthoughmundermsomemcircumstancesmamlicensedmnursemmaymdispensemprescribedmdrugsmbutmthis

mism
notmhismormhermmajormresponsibilityminmdrugmtherapy.mThempharmacymtechnicianmhasmthemmaj
ormresponsibilitymofmdispensingmprescribedmdrugsmundermthemdirectionmofmamlicensedmpharmacist.

DIF: CognitivemLevel:mRemembering REF: p.m3

2. Whichmtermmdescribesmthemeffectmofmamdrugmthatmimprovesmbodymfunction?
a. Sidemeffect
b Intendedmaction
.
c. Adversemreaction
d Idiosyncraticmresponse
.


ANS:m B
Thempurposemofmdrugmtherapymismtomtakemamdrugmtomprevent,mreduce,mormcorrectmamhealthmprobl
em.mThismresponsemismanymdrug’smintendedmactionmalsomknownmasmamtherapeuticmresponse.

DIF: CognitivemLevel:mRemembering REF: p.m3

3. Whichmtypemofmdrugmnamemism―owned‖mbymthemcompanymthatmmanufacturesmit?
a. Genericmname
b Chemicalmname

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m m m


.
c. Categorymname
d Trademname
.


ANS:m D
Themchemicalmnamemismamdrug’smexactmchemicalmcomposition.mThemgenericmnamemismthemnamema
ssignedmtomthemdrugmbymthemU.S.mAdoptedmNamesmCouncilmandmismnotmownedmbymanyone.mThemc
ategorymnamemrefersmtomthemtypemofmdrugm(whatmitmdoesmormwhatmitmismusedmfor)mandmismnotmanmact
ualmdrugmname.mThemtrademnamem(brandmname)mismthemnamemprovidedmandmownedmbymamspecificm
drug’smmanufacturer.

DIF: CognitivemLevel:mRemembering REF: p.m4

4. Whichmdrugmormdrugmclassmismam―highmalert‖mdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.


ANS:m B
Amhighmalertmdrugmismoneminmwhichmharmmismlikelymtomresultmifmgivenmatmthemwrongmdose,mtomthemwr
ongmpatient,mormnotmgivenmtomthemcorrectmpatient.mDrugsmclassifiedmasmhighmalertmdrugsmincludempot
assium,mnarcoticsm(opioids),minsulin,mcancermchemotherapymdrugs,mandmheparinm(ormanymdrugmthatm
stronglymaffectsmbloodmclotting).mPenicillin,mNSAIDs,mandmcalciummaremnotmconsideredmhighmalertm
drugs.

DIF: CognitivemLevel:mRemembering REF: p.m4

5. Whatmismthemtermmformamdrugmthatmhasmthemsamemactionmasmamnaturallymoccurringmb
odymhormonemormenzyme?
a. Agonist
b Blockingmagent
.
c. Chemical
d Duplicator
.


ANS:m A
Amdrugmagonistmismanmextrinsicmdrugmthatmactivatesmthemreceptormsitesmofmamcellmandmmimicsm
themactionsmofmnaturallymoccurringmbodymsubstancesm(intrinsicmdrugs).mAmblockingmagentmism
amdrug

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m m m


antagonist.mAmchemicalmwouldmnotmnecessarilymbemamdrugmatmall.mAmduplicatormismnotmampharmacolo
gicmterm.

DIF: CognitivemLevel:mRemembering REF: pp.m6-7

6. Whichmtermmdescribesmhowmthembodymaffectsmdrugmactivity?
a. Drugmpotency
b Pharmacodynamics
.
c. Therapeuticmeffect
d Pharmacokinetics
.


ANS:m D
Themtermmpharmacokineticsmrefersmtomdrugmmetabolismmandmhowmthembodymchangesmamdrug.mPhar
macodynamicsmrefersmtomhowmamdrugmworksmtomchangembodymfunction.mDrugmpotencymrefersmtomho
wmstronglymormtomwhatmdegreemamdrugmexertsmitsmeffects.mThemtherapeuticmeffectmismclosermtompharm
acodynamics,mmeaningmhowmamdrugmworksmtomchangembodymfunction.

DIF: CognitivemLevel:mRemembering REF: p.m10

7. InmthemUnitedmStates,mwhichmgroupmismresponsiblemformenforcingmestablishedmstandardsmf
ormdrugmmanufacturing?
a. U.S.mPharmacopeia
b NationalmInstitutesmofmHealth
.
c. FoodmandmDrugmAdministration
d AssociationmofmPharmaceuticalmManufacturers
.


ANS:m C
ThemstandardsmformdrugmmanufacturemaremestablishedmbymthemU.S.mPharmacopeia.mThesemstandar
dsmaremenforcedmbymthemFoodmandmDrugmAdministration.mNeithermthemNationalmInstitutesmofmHeal
thmnormthemAssociationmofmPharmaceuticalmManufacturersmhasmanymauthoritymtomenforcemdrugmstan
dards.

DIF:mmmm CognitivemLevel:mRememberingmmmmmmmm REF:mmm p.m5

8. Whichmfactormismammajormdisadvantagemofmthemtransdermalmdrugmdeliverymroute?
a. Onlymamprescribermcanmadministermdrugsmbymthemtransdermalmrout
e.
b Transdermalmdrugsmmustmbemsterilemrathermthanmclean.
.
c. Firstmpassmdrugmlossmbymthismroutemismthemmostmextensive.
d Drugmabsorptionmismdependentmonmadequatemcirculation.

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m m m


.


ANS:m D
Oncemamtransdermalmdrugmmovesmthroughmthemskin,mitmmustmentermthembloodstreammtomreachmitsmtar
getmtissue.mIfmcirculationmismpoormtomthemareamwheremthemtransdermalmdrugmismapplied,mverymlittle,mif
many,mofmthemdrugmwillmreachmitsm targetmtissue.




DIF: CognitivemLevel:mRemembering REF: p.m12

9. Howmaremintrinsicmdrugsmdifferentmfrommextrinsicmdrugs?
a.Intrinsicmdrugsmaremmadembymthembody,mwhereasmextrinsicmdrugsmaremmademoutsidemthembody.
b Intrinsicmdrugsmaremadministeredmbymthemparenteralmroute,mwhereasmextrinsicmdrugsma
. remadministeredmbymthemoralmroute.
c.Extrinsicmdrugsmcanmonlymbemappliedmtomthemskinmormmucousmmembranes,mwhereasmintrinsic
drugsmaremtakenminternally.
d Extrinsicmdrugsmrequiremamprescriptionmformadministration,mwhereasmintrinsicmdrugsma
. remavailablemover-the-counter.


ANS:m A
Intrinsicmdrugsmaremthemhormones,menzymes,mandmothermchemicalsmmadembymthembodymthatmchang
emcellmactivity.mExtrinsicmdrugsmaremmanufacturedmfrommchemical,manimal,mormplantmsourcesmandm
mustmhavemammeansmofmenteringmthembodyminmordermtomchangemcellmactivity.

DIF: CognitivemLevel:mUnderstanding REF: p.m3

10. Ampatientmasksmwhymhismdrugmtomcontrolmhighmbloodmpressuremhasmonlymonemgenericmnamem
andmtwomdifferentmtrademnames.mWhatmismyourmbestmresponse?
a. ―Mostmdrugsmhavemdifferentmtrademnamesmthatmindicatemdifferentmdosages.‖
b ―Themtwomdifferentmtrademnamesmindicatemthatmonemismammorempuremandmsafermdrugmthanm
. themother.‖
c. ―Themgenericmnamemismthemactualmofficialmdrugmnamemandmthemtrademnamemismambrandmowned
mbym amspecificmmanufacturer.‖


d ―Ifmyoumhaveminsurance,myoumcanmgetmthemtrademnamemdrug,mwhichmismusuallymmoremexpensive
. thanm themgenericm namedm drug.‖


ANS:m C
ThemgenericmnamemismthemnamemassignedmtomthemdrugmbymthemU.S.mAdoptedmNamesmCouncilmandmi
smnotmownedmbymanyone.mThemtrademnamem(brandmname)mismthemnamemprovidedmandmownedmbymams
pecificmdrug’smmanufacturer.mMoremthanmonemmanufacturermcanmmakemandmsellmthemsamemdrugmatmt
hemsamemtimemundermamdifferentmtrademname.mRegardlessmofmtrademname,mallmdrugsmthatmhavemthems
amemgenericmnamemmustmbemalikeminmtheirmchemicalmcompositionmandmstrength.

DIF: CognitivemLevel:mApplyingmormHigher REF: pp.m3-4