PET/CT REGISTRY EXAM QUESTIONS
AND ANSWERS 100% CORRECT
Which radionuclides are possible radioactive contaminants in the eluent of an Rb82
generator? - ANSWER-Sr82 and Sr85
Negative ion PET cyclotrons accelerate which of the following types of particles? -
ANSWER-negatively charged hydrogen atoms
F18 is labeled to glucose using a chemical method known as? - ANSWER-nucleophilic
substitution
The bombarding particles used for the nuclear reactions that occur in a cyclotron must
have an energy of at least _______ MeV - ANSWER-8 (the higher the particle energy
and the higher the beam current, the greater the level of radioactivity produced)
The most common irradiation process of producing F18 with a 109.7 minute half-life is -
ANSWER-o18(p,n)F18
According to the US federal regulations, any product with a half life greater than
_______ minutes must pass quality control testing before it can be released for human
use. - ANSWER-20
As specified in the USP, F18-FDG must have a labeling efficiency of greater than -
ANSWER-90%
Which of the following quality control tests for FDG cannot be performed before patient
use? - ANSWER-sterility (it takes 14 days to perform)
The initial precursor molecule for producing F18-FDG is - ANSWER-mannose triflate
Because of the high amount of radioactivity, the production of PET
radiopharmaceuticals must be done in lead shielded hot cells and with an automated
system called a - ANSWER-cyclotron
A patient needs the administration of 12mCi FDG and the current concentration of the
FDG is 8.3mCi/ML. How much volume should be prepared? - ANSWER-1.44 mL
The weight of a patient is 134 LB and the physician has prescribed 0.14mCi/kg for this
procedure. How much activity should be prepared? - ANSWER-8.5 mCi
f18-FLT (fluorothymidine) is helpful in patients with cancer because the uptake
mechanism demonstrates the rate of - ANSWER-cellular proliferation
, What are the names for LORs that are experienced in PET? - ANSWER-True, random,
scatter
Myocardial perfusion studies may be performed with - ANSWER-N13-ammonia, O15-
water, Rb82- chloride
The localization mechanism of F18-sodium fluoride is by uptake - ANSWER-
hydroxyapatite crystals
Reduced spatial resolution of PET scanners at the edges of the detectors is caused by -
ANSWER-increases in randoms and scatter fraction
The difference in 3D versus 2D PET imaging is the use of - ANSWER-septa
Which PET photon interaction event takes place from different decaying atoms arriving
at opposing crystals within the coincidence timing window? - ANSWER-random
Myocardial perfusion studies may be preformed with all the following
radiopharmaceuticals except - ANSWER-F18-FDG
The localization mechanism of F18- sodium fluoride is by uptake - ANSWER-in
hydroxyapatite crystals
The primary source of energy for the heart is from - ANSWER-fatty acids
C11-Choline is used for imaging all of the following except - ANSWER-breast cancer
F18- FDOPA (fluorodopa) is used to evaluate - ANSWER-parkinsons disease
which PET radiopharmaceutical provides a noninvasive method to quantify tumor
hypoxia in solid tumors of the brain, head and neck cancers, and lung cancers? -
ANSWER-F18- FMISO (fluoromisonidazole)
The cyclotron production of 015 is performed by deuteron irradiation of - ANSWER-N14
The high energy positron defines the average distance between the decaying atom and
the point of annihilation. Which PET radionuclide creates the blurriest image due to this
phenomenon? - ANSWER-82RB
Annihilation photons do not travel at exactly 180 degrees apart. This effect is described
by the term - ANSWER-nonclinearity
Which process enhances the sensitivity of radiation detection in a GM detector? -
ANSWER-ionization, secondary ionization, and avalanche photodiode
AND ANSWERS 100% CORRECT
Which radionuclides are possible radioactive contaminants in the eluent of an Rb82
generator? - ANSWER-Sr82 and Sr85
Negative ion PET cyclotrons accelerate which of the following types of particles? -
ANSWER-negatively charged hydrogen atoms
F18 is labeled to glucose using a chemical method known as? - ANSWER-nucleophilic
substitution
The bombarding particles used for the nuclear reactions that occur in a cyclotron must
have an energy of at least _______ MeV - ANSWER-8 (the higher the particle energy
and the higher the beam current, the greater the level of radioactivity produced)
The most common irradiation process of producing F18 with a 109.7 minute half-life is -
ANSWER-o18(p,n)F18
According to the US federal regulations, any product with a half life greater than
_______ minutes must pass quality control testing before it can be released for human
use. - ANSWER-20
As specified in the USP, F18-FDG must have a labeling efficiency of greater than -
ANSWER-90%
Which of the following quality control tests for FDG cannot be performed before patient
use? - ANSWER-sterility (it takes 14 days to perform)
The initial precursor molecule for producing F18-FDG is - ANSWER-mannose triflate
Because of the high amount of radioactivity, the production of PET
radiopharmaceuticals must be done in lead shielded hot cells and with an automated
system called a - ANSWER-cyclotron
A patient needs the administration of 12mCi FDG and the current concentration of the
FDG is 8.3mCi/ML. How much volume should be prepared? - ANSWER-1.44 mL
The weight of a patient is 134 LB and the physician has prescribed 0.14mCi/kg for this
procedure. How much activity should be prepared? - ANSWER-8.5 mCi
f18-FLT (fluorothymidine) is helpful in patients with cancer because the uptake
mechanism demonstrates the rate of - ANSWER-cellular proliferation
, What are the names for LORs that are experienced in PET? - ANSWER-True, random,
scatter
Myocardial perfusion studies may be performed with - ANSWER-N13-ammonia, O15-
water, Rb82- chloride
The localization mechanism of F18-sodium fluoride is by uptake - ANSWER-
hydroxyapatite crystals
Reduced spatial resolution of PET scanners at the edges of the detectors is caused by -
ANSWER-increases in randoms and scatter fraction
The difference in 3D versus 2D PET imaging is the use of - ANSWER-septa
Which PET photon interaction event takes place from different decaying atoms arriving
at opposing crystals within the coincidence timing window? - ANSWER-random
Myocardial perfusion studies may be preformed with all the following
radiopharmaceuticals except - ANSWER-F18-FDG
The localization mechanism of F18- sodium fluoride is by uptake - ANSWER-in
hydroxyapatite crystals
The primary source of energy for the heart is from - ANSWER-fatty acids
C11-Choline is used for imaging all of the following except - ANSWER-breast cancer
F18- FDOPA (fluorodopa) is used to evaluate - ANSWER-parkinsons disease
which PET radiopharmaceutical provides a noninvasive method to quantify tumor
hypoxia in solid tumors of the brain, head and neck cancers, and lung cancers? -
ANSWER-F18- FMISO (fluoromisonidazole)
The cyclotron production of 015 is performed by deuteron irradiation of - ANSWER-N14
The high energy positron defines the average distance between the decaying atom and
the point of annihilation. Which PET radionuclide creates the blurriest image due to this
phenomenon? - ANSWER-82RB
Annihilation photons do not travel at exactly 180 degrees apart. This effect is described
by the term - ANSWER-nonclinearity
Which process enhances the sensitivity of radiation detection in a GM detector? -
ANSWER-ionization, secondary ionization, and avalanche photodiode
