Nagelhout Pharm 1, exam 1 UPDATED
ACTUAL Questions and CORRECT
Answers
Pharmacology - CORRECT ANSWER - the study of the effect of chemicals on living
tissue
Pharmacokinetics - CORRECT ANSWER - the study of the absorption, distribution,
metabolism and excretion of drugs (what the body does to the drug)
Pharmaceutics - CORRECT ANSWER - the formulation and preparation of drugs
pharmacoeconomics - CORRECT ANSWER - the study of the economic impact of drugs
toxicology - CORRECT ANSWER - the study of the harmful effects of chemicals
pharmacognosy - CORRECT ANSWER - the study of the medicinal uses of naturally
occurring compounds
pharmacy - CORRECT ANSWER - the preparation and dispensing of drugs
pharmacogenetics - CORRECT ANSWER - genetic influences by and on drugs
pharmacodynamics - CORRECT ANSWER - physiological and biochemical mechanism
of action of drugs
(e.g. receptor theory) (what the drugs do to the body)
pharmacogenomics - CORRECT ANSWER - identifies discrete genetic differences among
individuals that play a critical role in drug response
, pharmacoepidemiology - CORRECT ANSWER - is the study of the use and effects of
drugs on large groups of people
ED50 - CORRECT ANSWER - Effective dose in 50% of the population
TD50 - CORRECT ANSWER - Toxic Dose in 50% of the population
LD50 - CORRECT ANSWER - Lethal Dose in 50% of the population
Therapeutic index - CORRECT ANSWER - LD50/ED50
Therapeutic window - CORRECT ANSWER - TD50/ED50. Index for estimation of drug
dosage which can treat disease effectively while staying within the safety range
Two types of ligands - CORRECT ANSWER - Agonist or Antagonist
Reversible binding of ligands is called - CORRECT ANSWER - competitive binding (this
occurs with most drugs)
non-reversible binding of ligands is called - CORRECT ANSWER - noncompetitive/non
reversable. (example was with ASA and platelet binding. Once the ASA is bound to the platelet,
the ASA will not un bind. Must make new platelets in that time and stop taking ASA.
5 types of chemical bonds in order of increasing strength - CORRECT ANSWER - van der
waals, hydrophobic, hydrogen, ionic, covalent
5 types of chemical bonds in order of decreasing strength - CORRECT ANSWER -
covalent, ionic, hydrogen, hydrophobic, van der waals
ACTUAL Questions and CORRECT
Answers
Pharmacology - CORRECT ANSWER - the study of the effect of chemicals on living
tissue
Pharmacokinetics - CORRECT ANSWER - the study of the absorption, distribution,
metabolism and excretion of drugs (what the body does to the drug)
Pharmaceutics - CORRECT ANSWER - the formulation and preparation of drugs
pharmacoeconomics - CORRECT ANSWER - the study of the economic impact of drugs
toxicology - CORRECT ANSWER - the study of the harmful effects of chemicals
pharmacognosy - CORRECT ANSWER - the study of the medicinal uses of naturally
occurring compounds
pharmacy - CORRECT ANSWER - the preparation and dispensing of drugs
pharmacogenetics - CORRECT ANSWER - genetic influences by and on drugs
pharmacodynamics - CORRECT ANSWER - physiological and biochemical mechanism
of action of drugs
(e.g. receptor theory) (what the drugs do to the body)
pharmacogenomics - CORRECT ANSWER - identifies discrete genetic differences among
individuals that play a critical role in drug response
, pharmacoepidemiology - CORRECT ANSWER - is the study of the use and effects of
drugs on large groups of people
ED50 - CORRECT ANSWER - Effective dose in 50% of the population
TD50 - CORRECT ANSWER - Toxic Dose in 50% of the population
LD50 - CORRECT ANSWER - Lethal Dose in 50% of the population
Therapeutic index - CORRECT ANSWER - LD50/ED50
Therapeutic window - CORRECT ANSWER - TD50/ED50. Index for estimation of drug
dosage which can treat disease effectively while staying within the safety range
Two types of ligands - CORRECT ANSWER - Agonist or Antagonist
Reversible binding of ligands is called - CORRECT ANSWER - competitive binding (this
occurs with most drugs)
non-reversible binding of ligands is called - CORRECT ANSWER - noncompetitive/non
reversable. (example was with ASA and platelet binding. Once the ASA is bound to the platelet,
the ASA will not un bind. Must make new platelets in that time and stop taking ASA.
5 types of chemical bonds in order of increasing strength - CORRECT ANSWER - van der
waals, hydrophobic, hydrogen, ionic, covalent
5 types of chemical bonds in order of decreasing strength - CORRECT ANSWER -
covalent, ionic, hydrogen, hydrophobic, van der waals
