PsychPharm Quiz 1 Exam And Answers
(Revised & Updated).
Psychosis - Answer the core feature of schizophrenia and other conditions in the schizophrenia
Agitation is a psychiatric emergency T/F - Answer True
IM haloperidol should be administered with - or - to reduce the risk of severe EPS or dystonia - Answer
benztropine or diphenhydramine
severely agitated patients, we suggest using a - in combination with the antipsychotic(e.g. Haldol + - +
Cogentin. - Answer benzodiazepine- ie Lorazepam
Cogentin is a benztropine or benzodiazepine? - Answer benztropine
FGA block ___ receptors - Answer D2
Effective for positive symptoms• Can worsen negative symptoms secondary to ↓DAin the Mesocortical
pathway - Answer FGA
Decanoate - Answer long acting form of FGA
SGA/Atypical are first line treatment antipsychotics T/F - Answer True
FGA or SGA:
Fewer neurological S/E• Effective for both positive and negative symptoms• Can cause EPS but at a lower
risk• ↓ incidence of Tardive dyskinesia - Answer SGA
Serotonin-Dopamine antagonist (D2/5HT2A) - Answer SGA
, Metabolic side effects of SGA - Answer weight gain, HLD,hyperglycemia, Diabetes, HTN, Cardiac and
respiratory S/E
How often to check LFT for SGAs? Are they elevated or decreased? - Answer Elevated Liver function
tests (LFTs)- check yearly
FGA can cause QTC Prolongation T/F - Answer False, SGA
Antipsychotics can take up to - weeks for response - Answer 6-8 weeks
Typical Antipsychotic side Effects blockade of : - Answer blockade of :
histamine,
acetylcholine
, alpha 1
and other receptors
Typical Antipsychotic side Effects - Answer High antiadrenergic, anticholinergic and antihistaminic s/e
(e.g. sedation, weight gain)
2. Elevated liver enzymes, jaundice
3. Seizures - all antipsychotics lower the seizure threshold
4. Orthostatic hypotension
5. QTC prolongation - obtain baseline EKG
6. Sexual dysfunction
7. Rashes, photosensitivity
8. Elevated liver enzymes, EPS (Akathisia, dystonia, Parkinsonism)
9. **Hyperprolactinemia (decreased libido, galactorrhea, gynecomastia, impotence,amenorrhea)
10. Tardive dyskinesia11. Neuroleptic Malignant Syndrome (FALTERED)
Hyperprolactinemia - Answer (decreased libido, galactorrhea, gynecomastia, impotence,amenorrhea)
(Revised & Updated).
Psychosis - Answer the core feature of schizophrenia and other conditions in the schizophrenia
Agitation is a psychiatric emergency T/F - Answer True
IM haloperidol should be administered with - or - to reduce the risk of severe EPS or dystonia - Answer
benztropine or diphenhydramine
severely agitated patients, we suggest using a - in combination with the antipsychotic(e.g. Haldol + - +
Cogentin. - Answer benzodiazepine- ie Lorazepam
Cogentin is a benztropine or benzodiazepine? - Answer benztropine
FGA block ___ receptors - Answer D2
Effective for positive symptoms• Can worsen negative symptoms secondary to ↓DAin the Mesocortical
pathway - Answer FGA
Decanoate - Answer long acting form of FGA
SGA/Atypical are first line treatment antipsychotics T/F - Answer True
FGA or SGA:
Fewer neurological S/E• Effective for both positive and negative symptoms• Can cause EPS but at a lower
risk• ↓ incidence of Tardive dyskinesia - Answer SGA
Serotonin-Dopamine antagonist (D2/5HT2A) - Answer SGA
, Metabolic side effects of SGA - Answer weight gain, HLD,hyperglycemia, Diabetes, HTN, Cardiac and
respiratory S/E
How often to check LFT for SGAs? Are they elevated or decreased? - Answer Elevated Liver function
tests (LFTs)- check yearly
FGA can cause QTC Prolongation T/F - Answer False, SGA
Antipsychotics can take up to - weeks for response - Answer 6-8 weeks
Typical Antipsychotic side Effects blockade of : - Answer blockade of :
histamine,
acetylcholine
, alpha 1
and other receptors
Typical Antipsychotic side Effects - Answer High antiadrenergic, anticholinergic and antihistaminic s/e
(e.g. sedation, weight gain)
2. Elevated liver enzymes, jaundice
3. Seizures - all antipsychotics lower the seizure threshold
4. Orthostatic hypotension
5. QTC prolongation - obtain baseline EKG
6. Sexual dysfunction
7. Rashes, photosensitivity
8. Elevated liver enzymes, EPS (Akathisia, dystonia, Parkinsonism)
9. **Hyperprolactinemia (decreased libido, galactorrhea, gynecomastia, impotence,amenorrhea)
10. Tardive dyskinesia11. Neuroleptic Malignant Syndrome (FALTERED)
Hyperprolactinemia - Answer (decreased libido, galactorrhea, gynecomastia, impotence,amenorrhea)
