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Samenvatting blok Exercise Physiology

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A summary of elective 2.3 Medicine - Maastricht University. Lectures and Cases.

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Summary course 2.3 Exercise
Physiology
Week 1: Muscle Force and Energy

Lectures:

Block opening lecture – Richard Cornelussen

Exercise Physiology = the study of how the body (cell, tissue, organ or system level) responds
in function and structure to (1) acute exercise stress, and (2) chronic physical activity.
Including metabolic changes and adaptations

Physical activity = body movement produced by muscle action that increases energy
expenditure. Like: activities of daily living such as shopping, gardening, housekeeping, child
bearing, work related activities.

Exercise = planned, structured, repetitive, and purposeful physical activity. Like: Training for
or performing athletics, sports, or recreational activities such as jogging, roller-blading, ice
skating and swimming.

Plato said 400 BC: Lack of activity destroys the good condition of every human being, while
movement and methodical physical exercise saves it and preserves it.

When is exercise enough?




Lecture neuromuscular function – Frits Prinzen

The chain of events of muscle contraction:

, Anatomy and histology of skeletal muscle:
- Muscle fasciculus
- Muscle fibers: 1-40 mm long, 10-100 microns wide.
- Myofibrils
- Sarcomeres: Z-disk, M-line, A-band, I-band
o Myosin (thick filament)
 Myosin heads
o Actin (thin filament)
 Surrounded by tropomyosin and
troponin complexes
o Titin

Length force and force-velocity relations:
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