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NBME CBSE - QUESTIONSANDANSWERS ACTUAL TESTLATESTUPDATE 2023/2024 BESTEXAMSOLUTION GRADEDA+

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NBME CBSE - QUESTIONSANDANSWERS ACTUAL TESTLATESTUPDATE 2023/2024 BESTEXAMSOLUTION GRADEDA+68 year old - 1 day history of fever and swelling in left leg - cellulitis- gram stain - gram positive, catalase negative cocci - clear zonesofblood agar - Which species of Streptococcus? Correct Ans - StrepPyogenes 67 year old woman - bicuspid aortic valve - admitted to thehospital - 2 day history of fever and chills. Blood culture grows viridansstreptococci - In addition to penicillin, which other drug is administeredto shorten the duration of treatment? Correct Ans - Bindingto30Sprotein 54-year-old - ECG shows P wave and R wave no relation betweenthetwo. Which is the most likely diagnosis? Correct Ans - ThirdDegree AV Block 42 year old - constipation, abdominal discomfort, mild fatigue, CAincreased, P04 decreased, treated for renal calculus - PE shows nowabnormalities - Most likely cause of patients condition is a small well defined nodule in which location? Correct Ans - ParathyroidGland 62 year old woman - osteoporosis - a bisphosphonate is prescribed. Theexpected beneficial effect of the drug is due to which of thefollowing?Correct Ans - Decreased Osteoclast Activity Cohot Study of elderly women - relative risk ratio for hip fracturesamong those who exercise regularly is 1.2 (95% confidence interval of1.1 to 1.8). Which of the following is the conclusion about theeffectofexercise on the risk of hip fracture? Correct Ans - StatisticallySignificant Overall Increase Risk 52 year old man goes to ER with chest pain radiating to his jawwhileshoveling snow. Pulse is 80/min and blood pressure is 130/70. Themost immediate treatment mechanism of action? Correct Ans- Increased nitric oxide concentration 27 year old man- MVC - skull x-ray shows a linear, nondepressedbasal skull fracture - increased serum osm and decreased urin osm. Followingdesmopressin urine osm increases. Desmopressin's effect is duetotheactivation of which of the following? Correct Ans - a. Adenylyl Cyclase Adenylate Cyclase - ATP - CAMP -- PROTEKINASE A -- Ca v2A 10 month old boy - 4 day history of fever and cough. He attendsdaycare center. Chest exam shows intercostal retractions along withbilateral, diffuse wheezes and expiratory rhonchi. The infectiousagentmost likely has which of the following properties? Correct Ans- Mediation of Cell Entry via a fusion protein A 17 year old girl in ED - 15 minutes after being stung by a bee. Mild light headedness but no difficulty swallowing- Bilateral wheezing- Which is most appropriate pharmacotherapy for this patient?Correct Ans - B2- Agonist 14 year old boy - 2 day history of sore throat and fever that peaksinlate afternoon. 1 week of fatigue. He recentaly had sex withonepartner. Physical exam show cervical lymphadenopathy andpharyngealerythema with a creamy exudate. DX? Correct Ans - InfectiousMononucleosis 57 year old man - radiation therapy for squamous cell carcinomaof thelung. Despite therapy, tumor increases in size and he dies 6monthslater. The progressive tumor growth is due to a defect in cell cyclearrest in which of the following phases of cell cycle? Correct Ans- G1 28 year old - lived in sub-Saharan Africa - until he came totheUS. Tempof 100.4 - imaging shows bilateral hydroureter and hydronephrosis. Biopsy shows marked fibrosis and scattered granulomas. DX?Correct Ans - Schistosomiasis A couple with a family history of a-thalassemia. Woman has onegenedeletion and man has two gene deletion. If the two gene is trans- whatpercentage of offspring will have a two gene deletion? Correct Ans- 50% previously healthy 40 year brought to emergency department byherhusband - 2 day history of fever, lethargy, confusion. PE shows scattered petechiae and ecchymoses over the lower extremities- 3+polychromasia and 3+ schistocytes and Low platelets Dx? CorrectAns - Thrombotic Thrombocytopenia Purpura 49 year old woman - coronary artery disease - BP 140/90 - HighCholesterol, High LDL (190), High triglycerides (350) - TX withatorvastatin and losartan. What are the effects on HDL andTriglycerides? Correct Ans - HDL increased Triglycerides Decreased

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NBME CBSE - QUESTIONS AND
ANSWERS ACTUAL TEST LATEST
UPDATE 2023/2024 BEST EXAM
SOLUTION GRADED A+
68 year old - 1 day history of fever and swelling in left leg - cellulitis
- gram stain - gram positive, catalase negative cocci - clear zones of
blood agar - Which species of Streptococcus? Correct Ans - Strep
Pyogenes

67 year old woman - bicuspid aortic valve - admitted to the hospital
- 2 day history of fever and chills. Blood culture grows viridans
streptococci - In addition to penicillin, which other drug is administered
to shorten the duration of treatment? Correct Ans - Binding to 30S
protein

54-year-old - ECG shows P wave and R wave no relation between the
two. Which is the most likely diagnosis? Correct Ans - Third
Degree AV Block

42 year old - constipation, abdominal discomfort, mild fatigue, CA
increased, P04 decreased, treated for renal calculus - PE shows now

abnormalities - Most likely cause of patients condition is a small well
defined nodule in which location? Correct Ans - Parathyroid
Gland

,62 year old woman - osteoporosis - a bisphosphonate is prescribed. The
expected beneficial effect of the drug is due to which of the following?
Correct Ans - Decreased Osteoclast Activity

Cohot Study of elderly women - relative risk ratio for hip fractures
among those who exercise regularly is 1.2 (95% confidence interval of
1.1 to 1.8). Which of the following is the conclusion about the effect of
exercise on the risk of hip fracture? Correct Ans - Statistically
Significant Overall Increase Risk

52 year old man goes to ER with chest pain radiating to his jaw while
shoveling snow. Pulse is 80/min and blood pressure is 130/70. The
most immediate treatment mechanism of action? Correct Ans
- Increased nitric oxide concentration



27 year old man- MVC - skull x-ray shows a linear, nondepressed basal
skull fracture - increased serum osm and decreased urin osm. Following
desmopressin urine osm increases. Desmopressin's effect is due to the
activation of which of the following? Correct Ans - a. Adenylyl
Cyclase
Adenylate Cyclase - ATP - CAMP -- PROTEKINASE A -- Ca v2

A 10 month old boy - 4 day history of fever and cough. He attends day
care center. Chest exam shows intercostal retractions along with
bilateral, diffuse wheezes and expiratory rhonchi. The infectious agent
most likely has which of the following properties? Correct Ans -
Mediation of Cell Entry via a fusion protein

A 17 year old girl in ED - 15 minutes after being stung by a bee. Mild

, light headedness but no difficulty swallowing- Bilateral wheezing -
Which is most appropriate pharmacotherapy for this patient?
Correct Ans - B2- Agonist

14 year old boy - 2 day history of sore throat and fever that peaks in
late afternoon. 1 week of fatigue. He recentaly had sex with one
partner. Physical exam show cervical lymphadenopathy and pharyngeal
erythema with a creamy exudate. DX? Correct Ans - Infectious
Mononucleosis

57 year old man - radiation therapy for squamous cell carcinoma of the
lung. Despite therapy, tumor increases in size and he dies 6 months
later. The progressive tumor growth is due to a defect in cell cycle
arrest in which of the following phases of cell cycle? Correct Ans -
G1

28 year old - lived in sub-Saharan Africa - until he came to the US. Temp
of 100.4 - imaging shows bilateral hydroureter and hydronephrosis.
Biopsy shows marked fibrosis and scattered granulomas. DX?
Correct Ans - Schistosomiasis

A couple with a family history of a-thalassemia. Woman has one gene
deletion and man has two gene deletion. If the two gene is trans - what
percentage of offspring will have a two gene deletion? Correct Ans -
50%

previously healthy 40 year brought to emergency department by her
husband - 2 day history of fever, lethargy, confusion. PE shows
scattered petechiae and ecchymoses over the lower extremities - 3+
polychromasia and 3+ schistocytes and Low platelets Dx? Correct Ans

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