lGI Meds
Class/ Generic/Trade How it works Uses Nrsg implications
Bulk Forming Laxative Combines with water in the Simple or chronic constipation, Administer with full glass of
psyllium (Metamucil) + intestinal contents to form an particularly associated with water, have patient to ingest at
emollient gel or viscous low-fiber diet. least 3,00 ml of fluid a day (if
solution that promotes Useful when straining should not contraindicated (HF)
peristalsis and reduced transit be avoided….MI, rectal Warn not to chew or to try to
time surgery, and prolonged bed rest swallow without water
Used in the management of
watery diarrhea
5-Aminosalicylate Locally acting anti- Reduction in the symptoms of Caution in salicylate allergy.
sulfasalazine (Azulfadine), inflammatory action I the ulcerative colitis or rheumatoid Headache, aplastic anemia.
mesalamine (Asacol), colon, where activity propabl a arthritis Administer with meals or after,
olsalazine (Dipentium)+ result of inhibition of with a full glass of whater. Don
prostaglandin synthesis not crush or chew enteric-
coated tablets
Teach to not stop when feeling
better. Long term therapy.\
Cross sensitivity with
furosemide, sulfonylurea
hypoglycemic agents.
Monitor in severe hepatic
impairment and blood
dyscrasias (diseases affecting
the blood and platletts)
Immunosuppressant Antagonizes purine metaboliam (Off-label use) Management of CAUTION: severe reanl
azathioprine (Imuran) with subsequent inhibition of Chron’s disease or ulcerative impairment.
DNA/RNA synthesis. colitis Watch for pulmonary edema
Suppression of cell-mediated With meals or after…may
immunity and altered antibody divide doses to minimize
formation nausea. Monitor for signs and
symptoms of infection
Pt will take temporarily for at
least 3 months.
Class/ Generic/Trade How it works Uses Nrsg implications
Bulk Forming Laxative Combines with water in the Simple or chronic constipation, Administer with full glass of
psyllium (Metamucil) + intestinal contents to form an particularly associated with water, have patient to ingest at
emollient gel or viscous low-fiber diet. least 3,00 ml of fluid a day (if
solution that promotes Useful when straining should not contraindicated (HF)
peristalsis and reduced transit be avoided….MI, rectal Warn not to chew or to try to
time surgery, and prolonged bed rest swallow without water
Used in the management of
watery diarrhea
5-Aminosalicylate Locally acting anti- Reduction in the symptoms of Caution in salicylate allergy.
sulfasalazine (Azulfadine), inflammatory action I the ulcerative colitis or rheumatoid Headache, aplastic anemia.
mesalamine (Asacol), colon, where activity propabl a arthritis Administer with meals or after,
olsalazine (Dipentium)+ result of inhibition of with a full glass of whater. Don
prostaglandin synthesis not crush or chew enteric-
coated tablets
Teach to not stop when feeling
better. Long term therapy.\
Cross sensitivity with
furosemide, sulfonylurea
hypoglycemic agents.
Monitor in severe hepatic
impairment and blood
dyscrasias (diseases affecting
the blood and platletts)
Immunosuppressant Antagonizes purine metaboliam (Off-label use) Management of CAUTION: severe reanl
azathioprine (Imuran) with subsequent inhibition of Chron’s disease or ulcerative impairment.
DNA/RNA synthesis. colitis Watch for pulmonary edema
Suppression of cell-mediated With meals or after…may
immunity and altered antibody divide doses to minimize
formation nausea. Monitor for signs and
symptoms of infection
Pt will take temporarily for at
least 3 months.
