MT AAB Chemistry Exam With Complete
Solutions A+ Graded
What are the roles of proteins? - ANSWER -Transport of metabolic products.
-part of the cell membranes.
-part of hormones and receptors.
-part of Enzymes.
Proteins are made up of: - ANSWER -Carbon
-Oxygen
-Hydrogen
-Nitrogen (distinguishes proteins from carbohydrates & lipids).
-Sulfur
*Proteins have a very high molecular weight; therefore, they serve as very good
immunogens.
Which of the proteins are water-soluble? - ANSWER Albumin- Water-soluble
Globulins- Salt solutions dilute
Histones- Dilute acids
,Basic unit: Amino Acids are linked by what? - ANSWER Peptide bonds.
-Short chain hydrocarbons w/carboxyl and amine group.
*Each amino acid may act as an acid or a base.
What is the structure of peptide bonds? - ANSWER Primary Stucture: Sequence of
amino acids.
Secondary Structure: Hydrogen bonding.
Tertiary Structure: Disulfide bonding.
Quaternary Structure: Electrostatic Attraction.
What is protein denaturation? - ANSWER The change of protein structure.
Can be caused by:
-Change in temperature (rupture weak secondary & tertiary bonds)
-Change in pH (alter ionic charge)
-Hydrolysis
-UV light
What are Aminoacidopathies? - ANSWER Inherited disorders of amino acid metabolism
such as:
-Phenylketonuria
-Tyrosinemia
, -Alkaptonuria
-Maple Syrup Disease
-Cystinuria (not an enzyme deficiency)
Name the disorder:
Enzyme deficiency of phenylalanine hydrolase; which results in accumulation of
phenylalanine in blood and phenylpyruvic acid in urine? - ANSWER Phenylketonuria
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
*Testing includes PKU and Gutherie Tests
PKU and Gutherie Tests are used to diagnose what disorder? - ANSWER
Phenylketonuria
Name the disorder:
Enzyme deficiency of tyrosine aminotransfernase that results in the accumulation of
tyrosine? - ANSWER Tyrosinemia
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
Name the disorder:
An enzyme deficiency of homogentisic oxidase that results in the accumulation of
homogentisic acid? - ANSWER Alkaptonuria
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
Solutions A+ Graded
What are the roles of proteins? - ANSWER -Transport of metabolic products.
-part of the cell membranes.
-part of hormones and receptors.
-part of Enzymes.
Proteins are made up of: - ANSWER -Carbon
-Oxygen
-Hydrogen
-Nitrogen (distinguishes proteins from carbohydrates & lipids).
-Sulfur
*Proteins have a very high molecular weight; therefore, they serve as very good
immunogens.
Which of the proteins are water-soluble? - ANSWER Albumin- Water-soluble
Globulins- Salt solutions dilute
Histones- Dilute acids
,Basic unit: Amino Acids are linked by what? - ANSWER Peptide bonds.
-Short chain hydrocarbons w/carboxyl and amine group.
*Each amino acid may act as an acid or a base.
What is the structure of peptide bonds? - ANSWER Primary Stucture: Sequence of
amino acids.
Secondary Structure: Hydrogen bonding.
Tertiary Structure: Disulfide bonding.
Quaternary Structure: Electrostatic Attraction.
What is protein denaturation? - ANSWER The change of protein structure.
Can be caused by:
-Change in temperature (rupture weak secondary & tertiary bonds)
-Change in pH (alter ionic charge)
-Hydrolysis
-UV light
What are Aminoacidopathies? - ANSWER Inherited disorders of amino acid metabolism
such as:
-Phenylketonuria
-Tyrosinemia
, -Alkaptonuria
-Maple Syrup Disease
-Cystinuria (not an enzyme deficiency)
Name the disorder:
Enzyme deficiency of phenylalanine hydrolase; which results in accumulation of
phenylalanine in blood and phenylpyruvic acid in urine? - ANSWER Phenylketonuria
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
*Testing includes PKU and Gutherie Tests
PKU and Gutherie Tests are used to diagnose what disorder? - ANSWER
Phenylketonuria
Name the disorder:
Enzyme deficiency of tyrosine aminotransfernase that results in the accumulation of
tyrosine? - ANSWER Tyrosinemia
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
Name the disorder:
An enzyme deficiency of homogentisic oxidase that results in the accumulation of
homogentisic acid? - ANSWER Alkaptonuria
*Inherited
*Amino acid metabolism disorder (Aminoacidpathy)
