Notes - Survey in Biopsychology
Key Events at the Synapse
(lecture 4)
binding and activation of receptors
neurotransmitters, as a ligand, bind to receptors located on th
creates PSPs
receptor - a protein that contains binding sites specikc to one
each neurotransyitter is specikc mor a t;pe om receptorw h
receptor t;pes e5g5. dopayine has : receptor subt;pesD 1
receptor subt;pes are located in dixerent areas om the br
ad,antages to ha,ing yan; dixerent subt;pes om receptor
ha,e a ,ariet; om exects z Ce^ibilit;
ligand - an; yolecule that binds to another yolecule (receptor
om its receptor
classimcation of receptors
25 ionotropic - ligand-gated ion channels that are direct and
i5 vhen a neurotransyitter binds. the receptor open
Cov om ions intozout om the cell
35 yetabotropic - g-protein linfed (acti,ate second yesseng
indirect
i5 vhen a neurotransyitter binds. a part om the g-pro
a second yessengerw it vill either open ion channe
yessengers
terhinating tye activitu of nekrotranshitters
lastly, after the binding is done, not all neurotransmitters will b
leftover neurotransmitters must be taken care of
reuptafe - reabsorption om a neurotransyitter b; the pres;nap
degradation - neurotransyitters are brofen dovn b; the actio
a5 suntyesis - neurotransyitters are yade mroy en+;yes
Key Events at the Synapse
(lecture 4)
binding and activation of receptors
neurotransmitters, as a ligand, bind to receptors located on th
creates PSPs
receptor - a protein that contains binding sites specikc to one
each neurotransyitter is specikc mor a t;pe om receptorw h
receptor t;pes e5g5. dopayine has : receptor subt;pesD 1
receptor subt;pes are located in dixerent areas om the br
ad,antages to ha,ing yan; dixerent subt;pes om receptor
ha,e a ,ariet; om exects z Ce^ibilit;
ligand - an; yolecule that binds to another yolecule (receptor
om its receptor
classimcation of receptors
25 ionotropic - ligand-gated ion channels that are direct and
i5 vhen a neurotransyitter binds. the receptor open
Cov om ions intozout om the cell
35 yetabotropic - g-protein linfed (acti,ate second yesseng
indirect
i5 vhen a neurotransyitter binds. a part om the g-pro
a second yessengerw it vill either open ion channe
yessengers
terhinating tye activitu of nekrotranshitters
lastly, after the binding is done, not all neurotransmitters will b
leftover neurotransmitters must be taken care of
reuptafe - reabsorption om a neurotransyitter b; the pres;nap
degradation - neurotransyitters are brofen dovn b; the actio
a5 suntyesis - neurotransyitters are yade mroy en+;yes
