ATI PHARMACOLOGY RN QUESTIONS AND ANSWERS
Digoxin (lanoxin) SE - Answers- blurred/double vision
Guaifenesin SE - Answers- can cause drowsiness
Estrogen (premarin) SE - Answers- ↑ risk of Thromboembolism with s/s: SOB, severe
headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - Answers- urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answers- with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit
the therapeutic effects Use: invert canister, shake before use, rinse mouth after use,
w/new inhaler perform test spray
Levothryoxine (T4) Indication - Answers- hypothyroidism RT dysfxn of hypothalamus,
pituitary, or thyroid gland
Cephalosporins (Keflex) - Answers- allergy to cephalosporins is considered a
precaution for taking penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answers-
assess for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
Sumatriptan (Imitrex) use - Answers- when migraine symptoms appear and again in 1
hr if symptoms persist
Route—fastest/most effective - Answers- intravenous
Narcan [opioid antagonist] - Answers- therapeutic action: improvement of respiratory
rate
Baclofen (Lioresal) Therapeutic action - Answers- ↓ frequency & severity of muscle
spasms
Erythromycin (Erythrocin) [macrolide] SE - Answers- liver toxicity
Loperamide (Imodium) use - Answers- anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - Answers- bulk-forming agent with minimal Side Effects
(SE)
, Psyllium (Metamucil) use - Answers- bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - Answers- edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - Answers- Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
Norgestrel (Ovrette) use and contraindication - Answers- contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
IM injection site - Answers- locate dorsogluteal site
Nausea tx - Answers- antiemetic plus cool, damp cloth to forehead, neck, and wrists.
Allopurinol (Zyloprim) indication - Answers- Gout; MofA: ↓ serum uric acid levels &
urinary uric acid secretion; Precaution: avoid foods that acidify urine such as corn
TB—multi drug tx - Answers- Isoniazid(INH), Rifampin, pyrazinamide, ethambutol—to
deal w/ resistant strains
ACE Inhib. Lisinopril (Zestril) SE - Answers- dry/persistent cough for 1-2 wks from ↑
bradykinin
Furosemide (Lasix) [loop diuretic] Intervention - Answers- check BP before giving to
determine baseline; can cause ↓ BP by ↓ circulatory volume or by relaxing venous
smooth muscle
What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answers- foods w/ ↑ K such as salt substitutes
Chloroquine phosphate (Aralen): Indication - Answers- malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - Answers- w/alteplase for acute MI
Warfarin (Coumadin) Use - Answers- long-term prophylaxis of thrombosis [antidote—Vit
K]
Digoxin (lanoxin) SE - Answers- blurred/double vision
Guaifenesin SE - Answers- can cause drowsiness
Estrogen (premarin) SE - Answers- ↑ risk of Thromboembolism with s/s: SOB, severe
headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - Answers- urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answers- with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit
the therapeutic effects Use: invert canister, shake before use, rinse mouth after use,
w/new inhaler perform test spray
Levothryoxine (T4) Indication - Answers- hypothyroidism RT dysfxn of hypothalamus,
pituitary, or thyroid gland
Cephalosporins (Keflex) - Answers- allergy to cephalosporins is considered a
precaution for taking penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answers-
assess for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
Sumatriptan (Imitrex) use - Answers- when migraine symptoms appear and again in 1
hr if symptoms persist
Route—fastest/most effective - Answers- intravenous
Narcan [opioid antagonist] - Answers- therapeutic action: improvement of respiratory
rate
Baclofen (Lioresal) Therapeutic action - Answers- ↓ frequency & severity of muscle
spasms
Erythromycin (Erythrocin) [macrolide] SE - Answers- liver toxicity
Loperamide (Imodium) use - Answers- anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - Answers- bulk-forming agent with minimal Side Effects
(SE)
, Psyllium (Metamucil) use - Answers- bulk-forming agent with minimal Side Effects (SE)
Acetazolamide (Diamox) [diuretic] indication - Answers- edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - Answers- Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
Norgestrel (Ovrette) use and contraindication - Answers- contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
IM injection site - Answers- locate dorsogluteal site
Nausea tx - Answers- antiemetic plus cool, damp cloth to forehead, neck, and wrists.
Allopurinol (Zyloprim) indication - Answers- Gout; MofA: ↓ serum uric acid levels &
urinary uric acid secretion; Precaution: avoid foods that acidify urine such as corn
TB—multi drug tx - Answers- Isoniazid(INH), Rifampin, pyrazinamide, ethambutol—to
deal w/ resistant strains
ACE Inhib. Lisinopril (Zestril) SE - Answers- dry/persistent cough for 1-2 wks from ↑
bradykinin
Furosemide (Lasix) [loop diuretic] Intervention - Answers- check BP before giving to
determine baseline; can cause ↓ BP by ↓ circulatory volume or by relaxing venous
smooth muscle
What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answers- foods w/ ↑ K such as salt substitutes
Chloroquine phosphate (Aralen): Indication - Answers- malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - Answers- w/alteplase for acute MI
Warfarin (Coumadin) Use - Answers- long-term prophylaxis of thrombosis [antidote—Vit
K]
