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Rush - Advanced Pharmacology -
NSG 531 - Exam 4 Questions and
Correct Answers the Latest Update
Ginseng
✓ taken for:
✓ Nervousness, Agitation, Insomnia, Diarrhea, Headaches, Heart Palpitation
✓
✓ Do not take with MAO inhibitors. Can alter affects with heart medications. Can
increase the risk of bleeding when taken with blood clotting drugs
✓ CI: Neuro, Heart, MAO, bleeding, coag drugs
Ma Huang (Ephedra)
✓ Dangerously elevate blood pressure, stimulate heart rate, and CNS
✓ Associated with stroke, MI, and death
✓ Banned > 10 mg in U.S. with exception of traditional Asian medicine
✓ Metabolife
✓ Used for weight loss, allergies, asthma, bronchitis, fever, headache
arginine
✓ Arginine is used for treatment of heart and blood vessel conditions including
congestive heart failure (CHF), chest pain, high blood pressure, and coronary artery
disease.
✓
✓ Don't use if:
✓ excess body acid
✓ high levels of potassium in the blood
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✓ sickle cell anemia
✓ heart attack within the last 30 days
✓ renal tubular acidosis
✓ decreased kidney function
✓ Don't use with nitro
pt. education for herbs and nutrients
✓ 1. herbs and nutrients have bioactive properties and have the same safety issues as
drugs
✓ 2. always consult a reliable source before adding
✓ 3. consider when researching what are the credentials of the author of the website,
what evidence is there to support their claims, are there any financial interests to
influence the claims of the auther
biological basis of drug/herb/nutrient interactions
✓ absorption (changing pH or motility of the GI tract)
✓
✓ Distribution (displacing agents that are bound to plasma proteins
✓
✓ Biotransformation (inducing or inhibiting CYP450 enzymes)
✓
✓ receptor binding (competitive and noncompetitive antagonism
Gompertzian Kinetics
✓ Cancer cells lack of normal regulating factors leading to abnormal growth
✓
✓ You can go from 0 to 10^9 before symptoms
✓ This bounces because you go on and off of chemo
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